Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MSRB3 (methionine sulfoxide reductase B3)

Identity

Other namesDFNB74
HGNC (Hugo) MSRB3
LocusID (NCBI) 253827
Atlas_Id 43002
Location 12q14.3
Location_base_pair Starts at 65672423 and ends at 65860687 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MSRB3   27375
Cards
Entrez_Gene (NCBI)MSRB3  253827  methionine sulfoxide reductase B3
GeneCards (Weizmann)MSRB3
Ensembl hg19 (Hinxton)ENSG00000174099 [Gene_View]  chr12:65672423-65860687 [Contig_View]  MSRB3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000174099 [Gene_View]  chr12:65672423-65860687 [Contig_View]  MSRB3 [Vega]
ICGC DataPortalENSG00000174099
TCGA cBioPortalMSRB3
AceView (NCBI)MSRB3
Genatlas (Paris)MSRB3
WikiGenes253827
SOURCE (Princeton)MSRB3
Genomic and cartography
GoldenPath hg19 (UCSC)MSRB3  -     chr12:65672423-65860687 +  12q14.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MSRB3  -     12q14.3   [Description]    (hg38-Dec_2013)
EnsemblMSRB3 - 12q14.3 [CytoView hg19]  MSRB3 - 12q14.3 [CytoView hg38]
Mapping of homologs : NCBIMSRB3 [Mapview hg19]  MSRB3 [Mapview hg38]
OMIM613718   613719   
Gene and transcription
Genbank (Entrez)AK094185 AK122602 AK293084 AK299065 AK316365
RefSeq transcript (Entrez)NM_001031679 NM_001193460 NM_001193461 NM_198080
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_023441 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)MSRB3
Cluster EST : UnigeneHs.339024 [ NCBI ]
CGAP (NCI)Hs.339024
Alternative Splicing : Fast-db (Paris)GSHG0006804
Alternative Splicing GalleryENSG00000174099
Gene ExpressionMSRB3 [ NCBI-GEO ]     MSRB3 [ SEEK ]   MSRB3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXL7 (Uniprot)
NextProtQ8IXL7  [Medical]  [Publications]
With graphics : InterProQ8IXL7
Splice isoforms : SwissVarQ8IXL7 (Swissvar)
Catalytic activity : Enzyme1.8.4.- [ Enzyme-Expasy ]   1.8.4.-1.8.4.- [ IntEnz-EBI ]   1.8.4.- [ BRENDA ]   1.8.4.- [ KEGG ]   
Domains : Interpro (EBI)Met_Sox_Rdtase    Met_Sox_Rdtase_MsrB    Mss4-like   
Related proteins : CluSTrQ8IXL7
Domain families : Pfam (Sanger)SelR (PF01641)   
Domain families : Pfam (NCBI)pfam01641   
DMDM Disease mutations253827
Blocks (Seattle)Q8IXL7
Human Protein AtlasENSG00000174099
Peptide AtlasQ8IXL7
HPRD14785
IPIIPI00217550   IPI00479793   IPI01013461   IPI01013007   IPI01012074   IPI01011131   IPI01012459   IPI00941512   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXL7
IntAct (EBI)Q8IXL7
FunCoupENSG00000174099
BioGRIDMSRB3
IntegromeDBMSRB3
STRING (EMBL)MSRB3
Ontologies - Pathways
QuickGOQ8IXL7
Ontology : AmiGOprotein binding  mitochondrion  endoplasmic reticulum  response to oxidative stress  zinc ion binding  protein repair  peptide-methionine (R)-S-oxide reductase activity  oxidation-reduction process  
Ontology : EGO-EBIprotein binding  mitochondrion  endoplasmic reticulum  response to oxidative stress  zinc ion binding  protein repair  peptide-methionine (R)-S-oxide reductase activity  oxidation-reduction process  
Protein Interaction DatabaseMSRB3
DoCM (Curated mutations)MSRB3
Wikipedia pathwaysMSRB3
Gene fusion - Rearrangements
Gene fusion: TCGAMSRB3 JAZF1  MSRB3 BCL2L14  
Polymorphisms : SNP, variants
NCBI Variation ViewerMSRB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MSRB3
dbVarMSRB3
ClinVarMSRB3
1000_GenomesMSRB3 
Exome Variant ServerMSRB3
SNP (GeneSNP Utah)MSRB3
SNP : HGBaseMSRB3
Genetic variants : HAPMAPMSRB3
Genomic Variants (DGV)MSRB3 [DGVbeta]
Mutations
ICGC Data PortalMSRB3 
TCGA Data PortalMSRB3 
Tumor PortalMSRB3
Somatic Mutations in Cancer : COSMICMSRB3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:65672423-65860687
CONAN: Copy Number AnalysisMSRB3 
Mutations and Diseases : HGMDMSRB3
OMIM613718    613719   
MedgenMSRB3
NextProtQ8IXL7 [Medical]
GENETestsMSRB3
Disease Genetic AssociationMSRB3
Huge Navigator MSRB3 [HugePedia]  MSRB3 [HugeCancerGEM]
snp3D : Map Gene to Disease253827
DGIdb (Drug Gene Interaction db)MSRB3
BioCentury BCIQMSRB3
General knowledge
Homologs : HomoloGeneMSRB3
Homology/Alignments : Family Browser (UCSC)MSRB3
Phylogenetic Trees/Animal Genes : TreeFamMSRB3
Chemical/Protein Interactions : CTD253827
Chemical/Pharm GKB GenePA134991350
Clinical trialMSRB3
Cancer Resource (Charite)ENSG00000174099
Other databases
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
CoreMineMSRB3
GoPubMedMSRB3
iHOPMSRB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 11:56:44 CEST 2015

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