MSX1 (msh homeobox 1)

2010-12-01  

Identity

HGNC
LOCATION
4p16.2
LOCUSID
ALIAS
ECTD3,HOX7,HYD1,STHAG1
FUSION GENES

Other Information

Locus ID:

NCBI: 4487
MIM: 142983
HGNC: 7391
Ensembl: ENSG00000163132

Variants:

dbSNP: 4487
ClinVar: 4487
TCGA: ENSG00000163132
COSMIC: MSX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163132ENST00000382723P28360

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
194756672009SNCA variants are associated with increased risk for multiple system atrophy.110
128079592003Complete sequencing shows a role for MSX1 in non-syndromic cleft lip and palate.87
163278842005Medical sequencing of candidate genes for nonsyndromic cleft lip and palate.70
176930622007Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development.46
166009102006PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein.37
216266772011Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes.33
257384242015Circuit- and Diagnosis-Specific DNA Methylation Changes at γ-Aminobutyric Acid-Related Genes in Postmortem Human Hippocampus in Schizophrenia and Bipolar Disorder.32
205389602010A candidate gene study of obstructive sleep apnea in European Americans and African Americans.30
126519332003MSX1 and TGFB3 contribute to clefting in South America.26
205061122010BMP signaling in the human fetal ovary is developmentally regulated and promotes primordial germ cell apoptosis.26

Citation

Dessen P

MSX1 (msh homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-12-01

Online version: http://atlasgeneticsoncology.org/gene/51797/msx1