Identity
HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT-1A,MT-IA,MT1,MT1S,MTC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4489
MIM: 156350
HGNC: 7393
Ensembl: ENSG00000205362
Variants:
dbSNP: 4489
ClinVar: 4489
TCGA: ENSG00000205362
COSMIC: MT1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000205362 | ENST00000290705 | P04731 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA131285527 | oxaliplatin | Chemical | Literature, MultilinkAnnotation | associated | 24924344 | ||
| PA448486 | arsenic trioxide | Chemical | Literature, MultilinkAnnotation | associated | 24924344 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38490456 | 2024 | Human apo-metallothionein 1a is not a random coil: Evidence from guanidinium chloride, high temperature, and acidic pH unfolding studies. | 0 |
| 38490456 | 2024 | Human apo-metallothionein 1a is not a random coil: Evidence from guanidinium chloride, high temperature, and acidic pH unfolding studies. | 0 |
| 36981043 | 2023 | An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies. | 0 |
| 36981043 | 2023 | An Assessment of MT1A (rs11076161), MT2A (rs28366003) and MT1L (rs10636) Gene Polymorphisms and MT2 Concentration in Women with Endometrial Pathologies. | 0 |
| 33084977 | 2021 | Expression profiles of metallothionein-I/II and megalin/LRP-2 in uterine cervical squamous lesions. | 3 |
| 33084977 | 2021 | Expression profiles of metallothionein-I/II and megalin/LRP-2 in uterine cervical squamous lesions. | 3 |
| 32031554 | 2020 | pH dependence of the non-cooperative binding of Bi(3+) to human apo-metallothionein 1A: kinetics, speciation, and stoichiometry. | 4 |
| 32340109 | 2020 | Effects of Vitamin D Receptor, Metallothionein 1A, and 2A Gene Polymorphisms on Toxicity of the Peripheral Nervous System in Chronically Lead-Exposed Workers. | 3 |
| 32784815 | 2020 | Interplay between Carbonic Anhydrases and Metallothioneins: Structural Control of Metalation. | 5 |
| 32816651 | 2020 | Effect of metallothionein 1A rs8052394 polymorphism on lead, cadmium, zinc, and aluminum levels in factory workers. | 1 |
| 33225329 | 2020 | The pathways and domain specificity of Cu(I) binding to human metallothionein 1A. | 7 |
| 32031554 | 2020 | pH dependence of the non-cooperative binding of Bi(3+) to human apo-metallothionein 1A: kinetics, speciation, and stoichiometry. | 4 |
| 32340109 | 2020 | Effects of Vitamin D Receptor, Metallothionein 1A, and 2A Gene Polymorphisms on Toxicity of the Peripheral Nervous System in Chronically Lead-Exposed Workers. | 3 |
| 32784815 | 2020 | Interplay between Carbonic Anhydrases and Metallothioneins: Structural Control of Metalation. | 5 |
| 32816651 | 2020 | Effect of metallothionein 1A rs8052394 polymorphism on lead, cadmium, zinc, and aluminum levels in factory workers. | 1 |
Citation
Dessen P
MT1A (metallothionein 1A)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41439/mt1a
