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MT1A (metallothionein 1A)

Identity

Alias_namesMT1
MT1S
metallothionein 1S
Other aliasMTC
HGNC (Hugo) MT1A
LocusID (NCBI) 4489
Atlas_Id 41439
Location 16q12.2  [Link to chromosome band 16q12]
Location_base_pair Starts at 56672578 and ends at 56673999 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MT1A (16q12.2) / CABYR (18q11.2)TCF25 (16q24.3) / MT1A (16q12.2)TMEM151B (6p21.1) / MT1A (16q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MT1A   7393
Cards
Entrez_Gene (NCBI)MT1A  4489  metallothionein 1A
AliasesMT1; MT1S; MTC
GeneCards (Weizmann)MT1A
Ensembl hg19 (Hinxton)ENSG00000205362 [Gene_View]  chr16:56672578-56673999 [Contig_View]  MT1A [Vega]
Ensembl hg38 (Hinxton)ENSG00000205362 [Gene_View]  chr16:56672578-56673999 [Contig_View]  MT1A [Vega]
ICGC DataPortalENSG00000205362
TCGA cBioPortalMT1A
AceView (NCBI)MT1A
Genatlas (Paris)MT1A
WikiGenes4489
SOURCE (Princeton)MT1A
Genetics Home Reference (NIH)MT1A
Genomic and cartography
GoldenPath hg19 (UCSC)MT1A  -     chr16:56672578-56673999 +  16q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MT1A  -     16q12.2   [Description]    (hg38-Dec_2013)
EnsemblMT1A - 16q12.2 [CytoView hg19]  MT1A - 16q12.2 [CytoView hg38]
Mapping of homologs : NCBIMT1A [Mapview hg19]  MT1A [Mapview hg38]
OMIM156350   
Gene and transcription
Genbank (Entrez)AF348995 AY028617 BC029475 DQ892559 DQ895773
RefSeq transcript (Entrez)NM_005946
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)MT1A
Cluster EST : UnigeneHs.655199 [ NCBI ]
CGAP (NCI)Hs.655199
Alternative Splicing GalleryENSG00000205362
Gene ExpressionMT1A [ NCBI-GEO ]   MT1A [ EBI - ARRAY_EXPRESS ]   MT1A [ SEEK ]   MT1A [ MEM ]
Gene Expression Viewer (FireBrowse)MT1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4489
GTEX Portal (Tissue expression)MT1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04731   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04731  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04731
Splice isoforms : SwissVarP04731
PhosPhoSitePlusP04731
Domaine pattern : Prosite (Expaxy)METALLOTHIONEIN_VRT (PS00203)   
Domains : Interpro (EBI)Metalthion    Metalthion_dom    Metalthion_dom_vert    Metalthion_vert    Metalthion_vert_metal_BS   
Domain families : Pfam (Sanger)Metallothio (PF00131)   
Domain families : Pfam (NCBI)pfam00131   
Conserved Domain (NCBI)MT1A
DMDM Disease mutations4489
Blocks (Seattle)MT1A
SuperfamilyP04731
Human Protein AtlasENSG00000205362
Peptide AtlasP04731
HPRD07035
IPIIPI00025460   
Protein Interaction databases
DIP (DOE-UCLA)P04731
IntAct (EBI)P04731
FunCoupENSG00000205362
BioGRIDMT1A
STRING (EMBL)MT1A
ZODIACMT1A
Ontologies - Pathways
QuickGOP04731
Ontology : AmiGOprotein binding  nucleus  cytoplasm  cytosol  zinc ion binding  response to metal ion  negative regulation of growth  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to zinc ion  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  cytosol  zinc ion binding  response to metal ion  negative regulation of growth  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to zinc ion  
NDEx NetworkMT1A
Atlas of Cancer Signalling NetworkMT1A
Wikipedia pathwaysMT1A
Orthology - Evolution
OrthoDB4489
GeneTree (enSembl)ENSG00000205362
Phylogenetic Trees/Animal Genes : TreeFamMT1A
HOVERGENP04731
HOGENOMP04731
Homologs : HomoloGeneMT1A
Homology/Alignments : Family Browser (UCSC)MT1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMT1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MT1A
dbVarMT1A
ClinVarMT1A
1000_GenomesMT1A 
Exome Variant ServerMT1A
ExAC (Exome Aggregation Consortium)MT1A (select the gene name)
Genetic variants : HAPMAP4489
Genomic Variants (DGV)MT1A [DGVbeta]
DECIPHER (Syndromes)16:56672578-56673999  ENSG00000205362
CONAN: Copy Number AnalysisMT1A 
Mutations
ICGC Data PortalMT1A 
TCGA Data PortalMT1A 
Broad Tumor PortalMT1A
OASIS PortalMT1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMT1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMT1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MT1A
DgiDB (Drug Gene Interaction Database)MT1A
DoCM (Curated mutations)MT1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MT1A (select a term)
intoGenMT1A
Cancer3DMT1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM156350   
Orphanet
MedgenMT1A
Genetic Testing Registry MT1A
NextProtP04731 [Medical]
TSGene4489
GENETestsMT1A
Huge Navigator MT1A [HugePedia]
snp3D : Map Gene to Disease4489
BioCentury BCIQMT1A
ClinGenMT1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4489
Chemical/Pharm GKB GenePA31198
Clinical trialMT1A
Miscellaneous
canSAR (ICR)MT1A (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMT1A
EVEXMT1A
GoPubMedMT1A
iHOPMT1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:11:10 CEST 2017

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