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MT1B (metallothionein 1B)

Identity

Alias (NCBI)MT-1B
MT-IB
MT1
MT1Q
MTP
HGNC (Hugo) MT1B
HGNC Previous nameMT1
 MT1Q
HGNC Previous namemetallothionein 1Q
LocusID (NCBI) 4490
Atlas_Id 70528
Location 16q13  [Link to chromosome band 16q13]
Location_base_pair Starts at 56651899 and ends at 56653204 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MT1B   7394
Cards
Entrez_Gene (NCBI)MT1B  4490  metallothionein 1B
AliasesMT-1B; MT-IB; MT1; MT1Q; 
MTP
GeneCards (Weizmann)MT1B
Ensembl hg19 (Hinxton)ENSG00000169688 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169688 [Gene_View]  ENSG00000169688 [Sequence]  chr16:56651899-56653204 [Contig_View]  MT1B [Vega]
ICGC DataPortalENSG00000169688
TCGA cBioPortalMT1B
AceView (NCBI)MT1B
Genatlas (Paris)MT1B
WikiGenes4490
SOURCE (Princeton)MT1B
Genetics Home Reference (NIH)MT1B
Genomic and cartography
GoldenPath hg38 (UCSC)MT1B  -     chr16:56651899-56653204 +  16q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MT1B  -     16q13   [Description]    (hg19-Feb_2009)
GoldenPathMT1B - 16q13 [CytoView hg19]  MT1B - 16q13 [CytoView hg38]
ImmunoBaseENSG00000169688
genome Data Viewer NCBIMT1B [Mapview hg19]  
OMIM156349   
Gene and transcription
Genbank (Entrez)AF349000 AY168638 BC069421 BC137478 BC137479
RefSeq transcript (Entrez)NM_005947
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MT1B
Alternative Splicing GalleryENSG00000169688
Gene ExpressionMT1B [ NCBI-GEO ]   MT1B [ EBI - ARRAY_EXPRESS ]   MT1B [ SEEK ]   MT1B [ MEM ]
Gene Expression Viewer (FireBrowse)MT1B [ Firebrowse - Broad ]
GenevisibleExpression of MT1B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4490
GTEX Portal (Tissue expression)MT1B
Human Protein AtlasENSG00000169688-MT1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07438   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07438  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07438
Splice isoforms : SwissVarP07438
PhosPhoSitePlusP07438
Domaine pattern : Prosite (Expaxy)METALLOTHIONEIN_VRT (PS00203)   
Domains : Interpro (EBI)Metalthion    Metalthion_dom_sf    Metalthion_dom_sf_vert    Metalthion_vert    Metalthion_vert_metal_BS   
Domain families : Pfam (Sanger)Metallothio (PF00131)   
Domain families : Pfam (NCBI)pfam00131   
Conserved Domain (NCBI)MT1B
DMDM Disease mutations4490
Blocks (Seattle)MT1B
SuperfamilyP07438
Human Protein Atlas [tissue]ENSG00000169688-MT1B [tissue]
Peptide AtlasP07438
HPRD11826
IPIIPI00011655   
Protein Interaction databases
DIP (DOE-UCLA)P07438
IntAct (EBI)P07438
FunCoupENSG00000169688
BioGRIDMT1B
STRING (EMBL)MT1B
ZODIACMT1B
Ontologies - Pathways
QuickGOP07438
Ontology : AmiGOcell  nucleus  nucleus  cytoplasm  cytoplasm  cellular zinc ion homeostasis  zinc ion binding  detoxification of copper ion  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to copper ion  cellular response to zinc ion  cellular response to zinc ion  
Ontology : EGO-EBIcell  nucleus  nucleus  cytoplasm  cytoplasm  cellular zinc ion homeostasis  zinc ion binding  detoxification of copper ion  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to copper ion  cellular response to zinc ion  cellular response to zinc ion  
NDEx NetworkMT1B
Atlas of Cancer Signalling NetworkMT1B
Wikipedia pathwaysMT1B
Orthology - Evolution
OrthoDB4490
GeneTree (enSembl)ENSG00000169688
Phylogenetic Trees/Animal Genes : TreeFamMT1B
HOGENOMP07438
Homologs : HomoloGeneMT1B
Homology/Alignments : Family Browser (UCSC)MT1B
Gene fusions - Rearrangements
Fusion : QuiverMT1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMT1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MT1B
dbVarMT1B
ClinVarMT1B
1000_GenomesMT1B 
Exome Variant ServerMT1B
GNOMAD BrowserENSG00000169688
Varsome BrowserMT1B
Genetic variants : HAPMAP4490
Genomic Variants (DGV)MT1B [DGVbeta]
DECIPHERMT1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMT1B 
Mutations
ICGC Data PortalMT1B 
TCGA Data PortalMT1B 
Broad Tumor PortalMT1B
OASIS PortalMT1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMT1B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMT1B
Mutations and Diseases : HGMDMT1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MT1B
DgiDB (Drug Gene Interaction Database)MT1B
DoCM (Curated mutations)MT1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MT1B (select a term)
intoGenMT1B
Cancer3DMT1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM156349   
Orphanet
DisGeNETMT1B
MedgenMT1B
Genetic Testing Registry MT1B
NextProtP07438 [Medical]
TSGene4490
GENETestsMT1B
Target ValidationMT1B
Huge Navigator MT1B [HugePedia]
snp3D : Map Gene to Disease4490
BioCentury BCIQMT1B
ClinGenMT1B
Clinical trials, drugs, therapy
Protein Interactions : CTD4490
Pharm GKB GenePA31199
Clinical trialMT1B
Miscellaneous
canSAR (ICR)MT1B (select the gene name)
HarmonizomeMT1B
DataMed IndexMT1B
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMT1B
EVEXMT1B
GoPubMedMT1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:18:46 CEST 2020

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