MT1M (metallothionein 1M)

2013-03-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT-1M,MT-IM,MT1,MT1K

Other Information

Locus ID:

NCBI: 4499
MIM: 156357
HGNC: 14296
Ensembl: ENSG00000205364

Variants:

dbSNP: 4499
ClinVar: 4499
TCGA: ENSG00000205364
COSMIC: MT1M

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205364ENST00000379818Q8N339
ENSG00000205364ENST00000570233H3BUC6

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
229715772012Metallothionein MT1M is a tumor suppressor of human hepatocellular carcinomas.19
247826252014MT1M and MT1G promoter methylation as biomarkers for hepatocellular carcinoma.19
276500472016MiR-24-3p enhances cell growth in hepatocellular carcinoma by targeting metallothionein 1M.5
283804332017Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma.4
302273282018MiR-545-3p/MT1M axis regulates cell proliferation, invasion and migration in hepatocellular carcinoma.4
278083712016Low metallothionein 1M expression association with poor hepatocellular carcinoma prognosis after curative resection.3
294615972018The effect and mechanism of metallothionein MT1M on hepatocellular carcinoma cell.0
310023542019DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma.0

Citation

Dessen P

MT1M (metallothionein 1M)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53233/mt1m