Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MT1M (metallothionein 1M)

Identity

Alias_namesMT1
MT1K
metallothionein 1K
Other aliasMT-1M
MT-IM
HGNC (Hugo) MT1M
LocusID (NCBI) 4499
Atlas_Id 53233
Location 16q13  [Link to chromosome band 16q13]
Location_base_pair Starts at 56632622 and ends at 56633986 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MT1M   14296
Cards
Entrez_Gene (NCBI)MT1M  4499  metallothionein 1M
AliasesMT-1M; MT-IM; MT1; MT1K
GeneCards (Weizmann)MT1M
Ensembl hg19 (Hinxton)ENSG00000205364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205364 [Gene_View]  ENSG00000205364 [Sequence]  chr16:56632622-56633986 [Contig_View]  MT1M [Vega]
ICGC DataPortalENSG00000205364
TCGA cBioPortalMT1M
AceView (NCBI)MT1M
Genatlas (Paris)MT1M
WikiGenes4499
SOURCE (Princeton)MT1M
Genetics Home Reference (NIH)MT1M
Genomic and cartography
GoldenPath hg38 (UCSC)MT1M  -     chr16:56632622-56633986 +  16q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MT1M  -     16q13   [Description]    (hg19-Feb_2009)
EnsemblMT1M - 16q13 [CytoView hg19]  MT1M - 16q13 [CytoView hg38]
Mapping of homologs : NCBIMT1M [Mapview hg19]  MT1M [Mapview hg38]
OMIM156357   
Gene and transcription
Genbank (Entrez)AF136177 AF479613 BC028280 BC103841 BM918307
RefSeq transcript (Entrez)NM_176870
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MT1M
Cluster EST : UnigeneHs.647370 [ NCBI ]
CGAP (NCI)Hs.647370
Alternative Splicing GalleryENSG00000205364
Gene ExpressionMT1M [ NCBI-GEO ]   MT1M [ EBI - ARRAY_EXPRESS ]   MT1M [ SEEK ]   MT1M [ MEM ]
Gene Expression Viewer (FireBrowse)MT1M [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4499
GTEX Portal (Tissue expression)MT1M
Human Protein AtlasENSG00000205364-MT1M [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N339   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N339  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N339
Splice isoforms : SwissVarQ8N339
PhosPhoSitePlusQ8N339
Domaine pattern : Prosite (Expaxy)METALLOTHIONEIN_VRT (PS00203)   
Domains : Interpro (EBI)Metalthion    Metalthion_dom_sf    Metalthion_dom_sf_vert    Metalthion_vert    Metalthion_vert_metal_BS   
Domain families : Pfam (Sanger)Metallothio (PF00131)   
Domain families : Pfam (NCBI)pfam00131   
Conserved Domain (NCBI)MT1M
DMDM Disease mutations4499
Blocks (Seattle)MT1M
SuperfamilyQ8N339
Human Protein Atlas [tissue]ENSG00000205364-MT1M [tissue]
Peptide AtlasQ8N339
HPRD01129
IPIIPI00642651   
Protein Interaction databases
DIP (DOE-UCLA)Q8N339
IntAct (EBI)Q8N339
FunCoupENSG00000205364
BioGRIDMT1M
STRING (EMBL)MT1M
ZODIACMT1M
Ontologies - Pathways
QuickGOQ8N339
Ontology : AmiGOnucleus  nucleus  cytoplasm  cytoplasm  cellular zinc ion homeostasis  zinc ion binding  detoxification of copper ion  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to copper ion  cellular response to zinc ion  cellular response to zinc ion  
Ontology : EGO-EBInucleus  nucleus  cytoplasm  cytoplasm  cellular zinc ion homeostasis  zinc ion binding  detoxification of copper ion  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to copper ion  cellular response to zinc ion  cellular response to zinc ion  
Pathways : KEGGMineral absorption   
NDEx NetworkMT1M
Atlas of Cancer Signalling NetworkMT1M
Wikipedia pathwaysMT1M
Orthology - Evolution
OrthoDB4499
GeneTree (enSembl)ENSG00000205364
Phylogenetic Trees/Animal Genes : TreeFamMT1M
HOGENOMQ8N339
Homologs : HomoloGeneMT1M
Homology/Alignments : Family Browser (UCSC)MT1M
Gene fusions - Rearrangements
Fusion : QuiverMT1M
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMT1M [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MT1M
dbVarMT1M
ClinVarMT1M
1000_GenomesMT1M 
Exome Variant ServerMT1M
ExAC (Exome Aggregation Consortium)ENSG00000205364
GNOMAD BrowserENSG00000205364
Varsome BrowserMT1M
Genetic variants : HAPMAP4499
Genomic Variants (DGV)MT1M [DGVbeta]
DECIPHERMT1M [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMT1M 
Mutations
ICGC Data PortalMT1M 
TCGA Data PortalMT1M 
Broad Tumor PortalMT1M
OASIS PortalMT1M [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMT1M  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMT1M
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MT1M
DgiDB (Drug Gene Interaction Database)MT1M
DoCM (Curated mutations)MT1M (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MT1M (select a term)
intoGenMT1M
Cancer3DMT1M(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM156357   
Orphanet
DisGeNETMT1M
MedgenMT1M
Genetic Testing Registry MT1M
NextProtQ8N339 [Medical]
TSGene4499
GENETestsMT1M
Target ValidationMT1M
Huge Navigator MT1M [HugePedia]
snp3D : Map Gene to Disease4499
BioCentury BCIQMT1M
ClinGenMT1M
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4499
Chemical/Pharm GKB GenePA142671312
Clinical trialMT1M
Miscellaneous
canSAR (ICR)MT1M (select the gene name)
DataMed IndexMT1M
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMT1M
EVEXMT1M
GoPubMedMT1M
iHOPMT1M
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Feb 14 16:44:57 CET 2019
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