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MT1X (metallothionein 1X)

Identity

Alias_namesMT1
Alias_symbol (synonym)MT-1l
Other alias
HGNC (Hugo) MT1X
LocusID (NCBI) 4501
Atlas_Id 53262
Location 16q13  [Link to chromosome band 16q13]
Location_base_pair Starts at 56716382 and ends at 56718108 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MT1X (16q13) / RNF216 (7p22.1)RUSC1 (1q22) / MT1X (16q13)STEAP3 (2q14.2) / MT1X (16q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MT1X   7405
Cards
Entrez_Gene (NCBI)MT1X  4501  metallothionein 1X
AliasesMT-1l; MT1
GeneCards (Weizmann)MT1X
Ensembl hg19 (Hinxton)ENSG00000187193 [Gene_View]  chr16:56716382-56718108 [Contig_View]  MT1X [Vega]
Ensembl hg38 (Hinxton)ENSG00000187193 [Gene_View]  chr16:56716382-56718108 [Contig_View]  MT1X [Vega]
ICGC DataPortalENSG00000187193
TCGA cBioPortalMT1X
AceView (NCBI)MT1X
Genatlas (Paris)MT1X
WikiGenes4501
SOURCE (Princeton)MT1X
Genetics Home Reference (NIH)MT1X
Genomic and cartography
GoldenPath hg19 (UCSC)MT1X  -     chr16:56716382-56718108 +  16q13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MT1X  -     16q13   [Description]    (hg38-Dec_2013)
EnsemblMT1X - 16q13 [CytoView hg19]  MT1X - 16q13 [CytoView hg38]
Mapping of homologs : NCBIMT1X [Mapview hg19]  MT1X [Mapview hg38]
OMIM156359   
Gene and transcription
Genbank (Entrez)AK311284 AM393074 BC018190 BC029916 BC032131
RefSeq transcript (Entrez)NM_005952
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)MT1X
Cluster EST : UnigeneHs.374950 [ NCBI ]
CGAP (NCI)Hs.374950
Alternative Splicing GalleryENSG00000187193
Gene ExpressionMT1X [ NCBI-GEO ]   MT1X [ EBI - ARRAY_EXPRESS ]   MT1X [ SEEK ]   MT1X [ MEM ]
Gene Expression Viewer (FireBrowse)MT1X [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4501
GTEX Portal (Tissue expression)MT1X
Protein : pattern, domain, 3D structure
UniProt/SwissProtP80297   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP80297  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP80297
Splice isoforms : SwissVarP80297
PhosPhoSitePlusP80297
Domaine pattern : Prosite (Expaxy)METALLOTHIONEIN_VRT (PS00203)   
Domains : Interpro (EBI)Metalthion    Metalthion_dom    Metalthion_dom_vert    Metalthion_vert    Metalthion_vert_metal_BS   
Domain families : Pfam (Sanger)Metallothio (PF00131)   
Domain families : Pfam (NCBI)pfam00131   
Conserved Domain (NCBI)MT1X
DMDM Disease mutations4501
Blocks (Seattle)MT1X
SuperfamilyP80297
Human Protein AtlasENSG00000187193
Peptide AtlasP80297
HPRD01130
IPIIPI00008753   IPI00448762   
Protein Interaction databases
DIP (DOE-UCLA)P80297
IntAct (EBI)P80297
FunCoupENSG00000187193
BioGRIDMT1X
STRING (EMBL)MT1X
ZODIACMT1X
Ontologies - Pathways
QuickGOP80297
Ontology : AmiGOprotein binding  nucleus  cytoplasm  zinc ion binding  response to metal ion  cellular response to erythropoietin  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to zinc ion  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  zinc ion binding  response to metal ion  cellular response to erythropoietin  negative regulation of growth  metal ion binding  perinuclear region of cytoplasm  cellular response to cadmium ion  cellular response to zinc ion  
Pathways : KEGGMineral absorption   
NDEx NetworkMT1X
Atlas of Cancer Signalling NetworkMT1X
Wikipedia pathwaysMT1X
Orthology - Evolution
OrthoDB4501
GeneTree (enSembl)ENSG00000187193
Phylogenetic Trees/Animal Genes : TreeFamMT1X
HOVERGENP80297
HOGENOMP80297
Homologs : HomoloGeneMT1X
Homology/Alignments : Family Browser (UCSC)MT1X
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMT1X [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MT1X
dbVarMT1X
ClinVarMT1X
1000_GenomesMT1X 
Exome Variant ServerMT1X
ExAC (Exome Aggregation Consortium)MT1X (select the gene name)
Genetic variants : HAPMAP4501
Genomic Variants (DGV)MT1X [DGVbeta]
DECIPHER (Syndromes)16:56716382-56718108  ENSG00000187193
CONAN: Copy Number AnalysisMT1X 
Mutations
ICGC Data PortalMT1X 
TCGA Data PortalMT1X 
Broad Tumor PortalMT1X
OASIS PortalMT1X [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMT1X  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMT1X
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MT1X
DgiDB (Drug Gene Interaction Database)MT1X
DoCM (Curated mutations)MT1X (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MT1X (select a term)
intoGenMT1X
Cancer3DMT1X(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM156359   
Orphanet
MedgenMT1X
Genetic Testing Registry MT1X
NextProtP80297 [Medical]
TSGene4501
GENETestsMT1X
Huge Navigator MT1X [HugePedia]
snp3D : Map Gene to Disease4501
BioCentury BCIQMT1X
ClinGenMT1X
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4501
Chemical/Pharm GKB GenePA31213
Clinical trialMT1X
Miscellaneous
canSAR (ICR)MT1X (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMT1X
EVEXMT1X
GoPubMedMT1X
iHOPMT1X
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:17:32 CET 2017

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