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MTA2 (metastasis associated 1 family member 2)

Identity

Alias (NCBI)MTA1L1
PID
HGNC (Hugo) MTA2
HGNC Alias symbMTA1-L1
HGNC Previous nameMTA1L1
HGNC Previous namemetastasis associated gene family, member 2
LocusID (NCBI) 9219
Atlas_Id 41444
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62593214 and ends at 62601865 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAPNS1 (19q13.12)::MTA2 (11q12.3)EEF1G (11q12.3)::MTA2 (11q12.3)MTA2 (11q12.3)::MS4A18 (11q12.2)
MTA2 (11q12.3)::MTA2 (11q12.3)MTA2 (11q12.3)::PTMA (2q37.1)MTA2 (11q12.3)::SPIDR (8q11.21)
CAPNS1 19q13.12::MTA2 11q12.3MTA2 11q12.3::MS4A18 11q12.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MTA2   7411
Cards
Entrez_Gene (NCBI)MTA2    metastasis associated 1 family member 2
AliasesMTA1L1; PID
GeneCards (Weizmann)MTA2
Ensembl hg19 (Hinxton)ENSG00000149480 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149480 [Gene_View]  ENSG00000149480 [Sequence]  chr11:62593214-62601865 [Contig_View]  MTA2 [Vega]
ICGC DataPortalENSG00000149480
TCGA cBioPortalMTA2
AceView (NCBI)MTA2
Genatlas (Paris)MTA2
SOURCE (Princeton)MTA2
Genetics Home Reference (NIH)MTA2
Genomic and cartography
GoldenPath hg38 (UCSC)MTA2  -     chr11:62593214-62601865 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTA2  -     11q12.3   [Description]    (hg19-Feb_2009)
GoldenPathMTA2 - 11q12.3 [CytoView hg19]  MTA2 - 11q12.3 [CytoView hg38]
ImmunoBaseENSG00000149480
Genome Data Viewer NCBIMTA2 [Mapview hg19]  
OMIM603947   
Gene and transcription
Genbank (Entrez)AB016591 AF295807 AI380395 AK301569 AL561056
RefSeq transcript (Entrez)NM_001330292 NM_004739
Consensus coding sequences : CCDS (NCBI)MTA2
Gene ExpressionMTA2 [ NCBI-GEO ]   MTA2 [ EBI - ARRAY_EXPRESS ]   MTA2 [ SEEK ]   MTA2 [ MEM ]
Gene Expression Viewer (FireBrowse)MTA2 [ Firebrowse - Broad ]
GenevisibleExpression of MTA2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9219
GTEX Portal (Tissue expression)MTA2
Human Protein AtlasENSG00000149480-MTA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94776   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94776  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94776
PhosPhoSitePlusO94776
Domaine pattern : Prosite (Expaxy)BAH (PS51038)    ELM2 (PS51156)    SANT (PS51293)   
Domains : Interpro (EBI)BAH_dom    BAH_sf    ELM2_dom    Homeobox-like_sf    MIER/MTA    MTA1_R1    MTA2    SANT/Myb    SANT_dom    Znf_GATA   
Domain families : Pfam (Sanger)BAH (PF01426)    ELM2 (PF01448)    GATA (PF00320)    MTA_R1 (PF17226)   
Domain families : Pfam (NCBI)pfam01426    pfam01448    pfam00320    pfam17226   
Domain families : Smart (EMBL)BAH (SM00439)  ELM2 (SM01189)  SANT (SM00717)  ZnF_GATA (SM00401)  
Conserved Domain (NCBI)MTA2
SuperfamilyO94776
AlphaFold pdb e-kbO94776   
Human Protein Atlas [tissue]ENSG00000149480-MTA2 [tissue]
HPRD07233
Protein Interaction databases
DIP (DOE-UCLA)O94776
IntAct (EBI)O94776
BioGRIDMTA2
STRING (EMBL)MTA2
ZODIACMTA2
Ontologies - Pathways
QuickGOO94776
Ontology : AmiGOhistone deacetylase complex  negative regulation of transcription by RNA polymerase II  chromosome, telomeric region  chromatin  transcription coactivator activity  transcription corepressor activity  histone deacetylase activity  protein binding  nucleoplasm  nucleoplasm  nucleoplasm  transcription regulator complex  DNA methylation  chromatin assembly or disassembly  chromatin remodeling  chromatin remodeling  zinc ion binding  regulation of fibroblast migration  membrane  histone deacetylation  histone deacetylation  NuRD complex  NuRD complex  nucleosomal DNA binding  protein-containing complex  histone deacetylase binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  RNA polymerase II-specific DNA-binding transcription factor binding  
Ontology : EGO-EBIhistone deacetylase complex  negative regulation of transcription by RNA polymerase II  chromosome, telomeric region  chromatin  transcription coactivator activity  transcription corepressor activity  histone deacetylase activity  protein binding  nucleoplasm  nucleoplasm  nucleoplasm  transcription regulator complex  DNA methylation  chromatin assembly or disassembly  chromatin remodeling  chromatin remodeling  zinc ion binding  regulation of fibroblast migration  membrane  histone deacetylation  histone deacetylation  NuRD complex  NuRD complex  nucleosomal DNA binding  protein-containing complex  histone deacetylase binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  RNA polymerase II-specific DNA-binding transcription factor binding  
NDEx NetworkMTA2
Atlas of Cancer Signalling NetworkMTA2
Wikipedia pathwaysMTA2
Orthology - Evolution
OrthoDB9219
GeneTree (enSembl)ENSG00000149480
Phylogenetic Trees/Animal Genes : TreeFamMTA2
Homologs : HomoloGeneMTA2
Homology/Alignments : Family Browser (UCSC)MTA2
Gene fusions - Rearrangements
Fusion : MitelmanCAPNS1::MTA2 [19q13.12/11q12.3]  
Fusion : MitelmanMTA2::MS4A18 [11q12.3/11q12.2]  
Fusion : QuiverMTA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTA2
dbVarMTA2
ClinVarMTA2
MonarchMTA2
1000_GenomesMTA2 
Exome Variant ServerMTA2
GNOMAD BrowserENSG00000149480
Varsome BrowserMTA2
ACMGMTA2 variants
VarityO94776
Genomic Variants (DGV)MTA2 [DGVbeta]
DECIPHERMTA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTA2 
Mutations
ICGC Data PortalMTA2 
TCGA Data PortalMTA2 
Broad Tumor PortalMTA2
OASIS PortalMTA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTA2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMTA2
Mutations and Diseases : HGMDMTA2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMTA2
DgiDB (Drug Gene Interaction Database)MTA2
DoCM (Curated mutations)MTA2
CIViC (Clinical Interpretations of Variants in Cancer)MTA2
Cancer3DMTA2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603947   
Orphanet
DisGeNETMTA2
MedgenMTA2
Genetic Testing Registry MTA2
NextProtO94776 [Medical]
GENETestsMTA2
Target ValidationMTA2
Huge Navigator MTA2 [HugePedia]
ClinGenMTA2
Clinical trials, drugs, therapy
MyCancerGenomeMTA2
Protein Interactions : CTDMTA2
Pharm GKB GenePA31219
PharosO94776
Clinical trialMTA2
Miscellaneous
canSAR (ICR)MTA2
HarmonizomeMTA2
ARCHS4MTA2
DataMed IndexMTA2
Probes
Litterature
PubMed201 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMTA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:47:58 CET 2022

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