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MTAP (methylthioadenosine phosphorylase)

Identity

Other namesBDMF
DMSFH
DMSMFH
LGMBF
MSAP
c86fus
HGNC (Hugo) MTAP
LocusID (NCBI) 4507
Location 9p21.3
Location_base_pair Starts at 21802635 and ends at 21865969 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTAP   7413
Entrez_Gene (NCBI)MTAP  4507  methylthioadenosine phosphorylase
Cards
GeneCards (Weizmann)MTAP
Ensembl (Hinxton)ENSG00000099810 [Gene_View]  chr9:21802635-21865969 [Contig_View]  MTAP [Vega]
AceView (NCBI)MTAP
Genatlas (Paris)MTAP
SOURCE (Stanford)NM_002451
Genomic and cartography
GoldenPath (UCSC)MTAP  -  9p21.3   chr9:21802635-21865969 +  9p21.3   [Description]    (hg19-Feb_2009)
EnsemblMTAP - 9p21.3 [CytoView]
Mapping of homologs : NCBIMTAP [Mapview]
OMIM112250   156540   
Gene and transcription
Genbank (Entrez)AB062485 AF109294 AF216650 AK024734 AK300592
RefSeq transcript (SRS)NM_002451
RefSeq transcript (Entrez)NM_002451
RefSeq genomic (SRS)AC_000141 NC_000009 NC_018920 NG_032650 NT_008413 NW_001839149 NW_004078038
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_032650 NT_008413 NW_001839149 NW_004078038
Consensus coding sequences : CCDS (NCBI)MTAP
Cluster EST : UnigeneHs.193268 [ SRS ] Hs.193268 [ NCBI ]
CGAP (NCI)Hs.193268
Alternative Splicing GalleryENSG00000099810
Gene ExpressionMTAP [ NCBI-GEO ]   MTAP [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13126 (SRS) Q13126 (Uniprot)
NextProtQ13126
With graphics : InterProQ13126
Splice isoforms : SwissVarQ13126(Swissvar)
Domaine pattern : Prosite (SRS)PNP_MTAP_2 (PS01240)   
Domaine pattern : Prosite (Expaxy)PNP_MTAP_2 (PS01240)   
Domains : Interpro (SRS)MTAP    Nucleoside_phosphorylase_d    PNP/MTAP    Purine_phosphorylase-2_CS   
Domains : Interpro (EBI)MTAP    Nucleoside_phosphorylase_d    PNP/MTAP    Purine_phosphorylase-2_CS   
Related proteins : CluSTrQ13126
Domain families : Pfam (SRS)PNP_UDP_1 (PF01048)   
Domain families : Pfam (Sanger)PNP_UDP_1 (PF01048)   
Domain families : Pfam (NCBI)pfam01048   
DMDM4507
Blocks (Seattle)Q13126
PDB (SRS)1CB0    1CG6    1K27    1SD1    1SD2    3LN5    3OZC    3OZD    3OZE   
PDB (PDBSum)1CB0    1CG6    1K27    1SD1    1SD2    3LN5    3OZC    3OZD    3OZE   
PDB (IMB)1CB0    1CG6    1K27    1SD1    1SD2    3LN5    3OZC    3OZD    3OZE   
PDB (RSDB)1CB0    1CG6    1K27    1SD1    1SD2    3LN5    3OZC    3OZD    3OZE   
Human Protein AtlasENSG00000099810
HPRD01134
IPIIPI00011876   IPI00016626   IPI00386452   IPI00382958   IPI00915917   IPI00903024   
Protein Interaction databases
DIP (DOE-UCLA)Q13126
IntAct (EBI)Q13126
FunCoupENSG00000099810
REACTOMEMTAP
Protein Interaction Database4507
BioGRIDMTAP
InParanoidQ13126
Interologous Interaction database Q13126
IntegromeDBMTAP
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MTAP
SNP (GeneSNP Utah)MTAP
SNP : HGBaseMTAP
Genetic variants : HAPMAPMTAP
Somatic Mutations in Cancer : COSMICMTAP 
CONAN: Copy Number AnalysisMTAP 
Mutations and Diseases : HGMDMTAP
OMIM112250    156540   
GENETests112250    156540   
Disease Genetic AssociationMTAP
Huge Navigator MTAP [HugePedia]  MTAP [HugeCancerGEM]
Genomic VariantsMTAP  MTAP [DGVbeta]
ClinVarMTAP
snp3D : Map Gene to Disease4507
General knowledge
Homologs : HomoloGeneMTAP
Homology/Alignments : Family Browser (UCSC)MTAP
Phylogenetic Trees/Animal Genes : TreeFamMTAP
Catalytic activity : Enzyme2.4.2.28 [ Enzyme-Expasy ]   2.4.2.28 [ Enzyme-SRS ]   2.4.2.28 [ IntEnz-EBI ]   2.4.2.28 [ BRENDA ]   2.4.2.28 [ KEGG ]   
Chemical/Protein Interactions : CTD4507
Chemical/Pharm GKB GenePA31220
Clinical trialMTAP
Cancer Resource (Charite)ENSG00000099810
Ontology : AmiGOsulfur amino acid metabolic process  phosphorylase activity  nucleus  cytosol  nucleobase-containing compound metabolic process  purine ribonucleoside salvage  polyamine metabolic process  nicotinamide riboside catabolic process  S-methyl-5-thioadenosine phosphorylase activity  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  response to testosterone stimulus  cellular nitrogen compound metabolic process  small molecule metabolic process  
Ontology : EGO-EBIsulfur amino acid metabolic process  phosphorylase activity  nucleus  cytosol  nucleobase-containing compound metabolic process  purine ribonucleoside salvage  polyamine metabolic process  nicotinamide riboside catabolic process  S-methyl-5-thioadenosine phosphorylase activity  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  response to testosterone stimulus  cellular nitrogen compound metabolic process  small molecule metabolic process  
Other databases
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
PubGeneMTAP
iHOPMTAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:54:10 CEST 2013
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