Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MTCH1 (mitochondrial carrier 1)

Identity

Alias_namesmember 49
Alias_symbol (synonym)CGI-64
PSAP
SLC25A49
Other aliasPIG60
HGNC (Hugo) MTCH1
LocusID (NCBI) 23787
Atlas_Id 46691
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 36968135 and ends at 36986551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HYOU1 (11q23.3) / MTCH1 (6p21.2)MED12L (3q25.1) / MTCH1 (6p21.2)MTCH1 (6p21.2) / C3 (19p13.3)
MTCH1 (6p21.2) / HIVEP1 (6p24.1)MTCH1 (6p21.2) / MTCH1 (6p21.2)MTCH1 (6p21.2) / OGG1 (3p25.3)
OGG1 (3p25.3) / MTCH1 (6p21.2)SEH1L (18p11.21) / MTCH1 (6p21.2)SMPD4 (2q21.1) / MTCH1 (6p21.2)
USH1C (11p15.1) / MTCH1 (6p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTCH1   17586
Cards
Entrez_Gene (NCBI)MTCH1  23787  mitochondrial carrier 1
AliasesCGI-64; PIG60; PSAP; SLC25A49
GeneCards (Weizmann)MTCH1
Ensembl hg19 (Hinxton)ENSG00000137409 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137409 [Gene_View]  ENSG00000137409 [Sequence]  chr6:36968135-36986551 [Contig_View]  MTCH1 [Vega]
ICGC DataPortalENSG00000137409
TCGA cBioPortalMTCH1
AceView (NCBI)MTCH1
Genatlas (Paris)MTCH1
WikiGenes23787
SOURCE (Princeton)MTCH1
Genetics Home Reference (NIH)MTCH1
Genomic and cartography
GoldenPath hg38 (UCSC)MTCH1  -     chr6:36968135-36986551 -  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTCH1  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblMTCH1 - 6p21.2 [CytoView hg19]  MTCH1 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIMTCH1 [Mapview hg19]  MTCH1 [Mapview hg38]
OMIM610449   
Gene and transcription
Genbank (Entrez)AF151822 AF176006 AF189289 AF192559 AK022783
RefSeq transcript (Entrez)NM_001271641 NM_014341
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTCH1
Cluster EST : UnigeneHs.689540 [ NCBI ]
CGAP (NCI)Hs.689540
Alternative Splicing GalleryENSG00000137409
Gene ExpressionMTCH1 [ NCBI-GEO ]   MTCH1 [ EBI - ARRAY_EXPRESS ]   MTCH1 [ SEEK ]   MTCH1 [ MEM ]
Gene Expression Viewer (FireBrowse)MTCH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23787
GTEX Portal (Tissue expression)MTCH1
Human Protein AtlasENSG00000137409-MTCH1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZJ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZJ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZJ7
Splice isoforms : SwissVarQ9NZJ7
PhosPhoSitePlusQ9NZJ7
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mitochondrial_sb/sol_carrier    Mt_carrier_dom_sf   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)MTCH1
DMDM Disease mutations23787
Blocks (Seattle)MTCH1
SuperfamilyQ9NZJ7
Human Protein Atlas [tissue]ENSG00000137409-MTCH1 [tissue]
Peptide AtlasQ9NZJ7
HPRD14787
IPIIPI00386258   IPI00479697   IPI00739665   IPI00844338   IPI00554789   IPI00513776   IPI00514366   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZJ7
IntAct (EBI)Q9NZJ7
FunCoupENSG00000137409
BioGRIDMTCH1
STRING (EMBL)MTCH1
ZODIACMTCH1
Ontologies - Pathways
QuickGOQ9NZJ7
Ontology : AmiGOprotein binding  intracellular  mitochondrion  mitochondrion  mitochondrial inner membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  regulation of signal transduction  integral component of membrane  positive regulation of apoptotic process  positive regulation of apoptotic process  neuronal ion channel clustering  
Ontology : EGO-EBIprotein binding  intracellular  mitochondrion  mitochondrion  mitochondrial inner membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  regulation of signal transduction  integral component of membrane  positive regulation of apoptotic process  positive regulation of apoptotic process  neuronal ion channel clustering  
NDEx NetworkMTCH1
Atlas of Cancer Signalling NetworkMTCH1
Wikipedia pathwaysMTCH1
Orthology - Evolution
OrthoDB23787
GeneTree (enSembl)ENSG00000137409
Phylogenetic Trees/Animal Genes : TreeFamMTCH1
HOVERGENQ9NZJ7
HOGENOMQ9NZJ7
Homologs : HomoloGeneMTCH1
Homology/Alignments : Family Browser (UCSC)MTCH1
Gene fusions - Rearrangements
Fusion : QuiverMTCH1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTCH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTCH1
dbVarMTCH1
ClinVarMTCH1
1000_GenomesMTCH1 
Exome Variant ServerMTCH1
ExAC (Exome Aggregation Consortium)ENSG00000137409
GNOMAD BrowserENSG00000137409
Varsome BrowserMTCH1
Genetic variants : HAPMAP23787
Genomic Variants (DGV)MTCH1 [DGVbeta]
DECIPHERMTCH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTCH1 
Mutations
ICGC Data PortalMTCH1 
TCGA Data PortalMTCH1 
Broad Tumor PortalMTCH1
OASIS PortalMTCH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTCH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTCH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MTCH1
DgiDB (Drug Gene Interaction Database)MTCH1
DoCM (Curated mutations)MTCH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTCH1 (select a term)
intoGenMTCH1
Cancer3DMTCH1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610449   
Orphanet
DisGeNETMTCH1
MedgenMTCH1
Genetic Testing Registry MTCH1
NextProtQ9NZJ7 [Medical]
TSGene23787
GENETestsMTCH1
Target ValidationMTCH1
Huge Navigator MTCH1 [HugePedia]
snp3D : Map Gene to Disease23787
BioCentury BCIQMTCH1
ClinGenMTCH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23787
Chemical/Pharm GKB GenePA134958992
Clinical trialMTCH1
Miscellaneous
canSAR (ICR)MTCH1 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTCH1
EVEXMTCH1
GoPubMedMTCH1
iHOPMTCH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:24:08 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.