Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MTCH2 (mitochondrial carrier 2)

Identity

Alias_namesmitochondrial carrier homolog 2 (C. elegans)
Alias_symbol (synonym)SLC25A50
Other aliasHSPC032
MIMP
HGNC (Hugo) MTCH2
LocusID (NCBI) 23788
Atlas_Id 70536
Location 11p11.2  [Link to chromosome band 11p11]
Location_base_pair Starts at 47617306 and ends at 47642654 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CELF1 (11p11.2) / MTCH2 (11p11.2)MTCH2 (11p11.2) / FHIT (3p14.2)MTCH2 (11p11.2) / FNBP4 (11p11.2)
MTCH2 (11p11.2) / MTCH2 (11p11.2)MTCH2 (11p11.2) / TENM4 (11q14.1)MTCH2 FNBP4
MTCH2 FHIT

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTCH2   17587
Cards
Entrez_Gene (NCBI)MTCH2  23788  mitochondrial carrier 2
AliasesHSPC032; MIMP; SLC25A50
GeneCards (Weizmann)MTCH2
Ensembl hg19 (Hinxton)ENSG00000109919 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109919 [Gene_View]  chr11:47617306-47642654 [Contig_View]  MTCH2 [Vega]
ICGC DataPortalENSG00000109919
TCGA cBioPortalMTCH2
AceView (NCBI)MTCH2
Genatlas (Paris)MTCH2
WikiGenes23788
SOURCE (Princeton)MTCH2
Genetics Home Reference (NIH)MTCH2
Genomic and cartography
GoldenPath hg38 (UCSC)MTCH2  -     chr11:47617306-47642654 -  11p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTCH2  -     11p11.2   [Description]    (hg19-Feb_2009)
EnsemblMTCH2 - 11p11.2 [CytoView hg19]  MTCH2 - 11p11.2 [CytoView hg38]
Mapping of homologs : NCBIMTCH2 [Mapview hg19]  MTCH2 [Mapview hg38]
OMIM613221   
Gene and transcription
Genbank (Entrez)AF085361 AF176008 AK223097 AK295218 AK313032
RefSeq transcript (Entrez)NM_001317231 NM_001317232 NM_001317233 NM_014342
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTCH2
Cluster EST : UnigeneHs.269944 [ NCBI ]
CGAP (NCI)Hs.269944
Alternative Splicing GalleryENSG00000109919
Gene ExpressionMTCH2 [ NCBI-GEO ]   MTCH2 [ EBI - ARRAY_EXPRESS ]   MTCH2 [ SEEK ]   MTCH2 [ MEM ]
Gene Expression Viewer (FireBrowse)MTCH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23788
GTEX Portal (Tissue expression)MTCH2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6C9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6C9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6C9
Splice isoforms : SwissVarQ9Y6C9
PhosPhoSitePlusQ9Y6C9
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)MTCH2
DMDM Disease mutations23788
Blocks (Seattle)MTCH2
SuperfamilyQ9Y6C9
Human Protein AtlasENSG00000109919
Peptide AtlasQ9Y6C9
HPRD14788
IPIIPI00003833   IPI01015136   IPI00980410   IPI00983602   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6C9
IntAct (EBI)Q9Y6C9
FunCoupENSG00000109919
BioGRIDMTCH2
STRING (EMBL)MTCH2
ZODIACMTCH2
Ontologies - Pathways
QuickGOQ9Y6C9
Ontology : AmiGOnucleus  mitochondrion  mitochondrial outer membrane  mitochondrial inner membrane  lactate metabolic process  negative regulation of mitochondrial membrane potential  membrane  membrane  integral component of membrane  hematopoietic stem cell migration  mitochondrial ATP synthesis coupled electron transport  positive regulation of apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of glycolytic process  hematopoietic stem cell homeostasis  extracellular exosome  protein localization to mitochondrion  cellular response to radiation  establishment of protein localization to mitochondrial membrane involved in mitochondrial fission  hepatocyte apoptotic process  regulation of mitochondrial membrane permeability involved in apoptotic process  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
Ontology : EGO-EBInucleus  mitochondrion  mitochondrial outer membrane  mitochondrial inner membrane  lactate metabolic process  negative regulation of mitochondrial membrane potential  membrane  membrane  integral component of membrane  hematopoietic stem cell migration  mitochondrial ATP synthesis coupled electron transport  positive regulation of apoptotic process  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of glycolytic process  hematopoietic stem cell homeostasis  extracellular exosome  protein localization to mitochondrion  cellular response to radiation  establishment of protein localization to mitochondrial membrane involved in mitochondrial fission  hepatocyte apoptotic process  regulation of mitochondrial membrane permeability involved in apoptotic process  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
NDEx NetworkMTCH2
Atlas of Cancer Signalling NetworkMTCH2
Wikipedia pathwaysMTCH2
Orthology - Evolution
OrthoDB23788
GeneTree (enSembl)ENSG00000109919
Phylogenetic Trees/Animal Genes : TreeFamMTCH2
HOVERGENQ9Y6C9
HOGENOMQ9Y6C9
Homologs : HomoloGeneMTCH2
Homology/Alignments : Family Browser (UCSC)MTCH2
Gene fusions - Rearrangements
Fusion: TCGAMTCH2 FNBP4
Fusion: TCGAMTCH2 FHIT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTCH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTCH2
dbVarMTCH2
ClinVarMTCH2
1000_GenomesMTCH2 
Exome Variant ServerMTCH2
ExAC (Exome Aggregation Consortium)MTCH2 (select the gene name)
Genetic variants : HAPMAP23788
Genomic Variants (DGV)MTCH2 [DGVbeta]
DECIPHERMTCH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTCH2 
Mutations
ICGC Data PortalMTCH2 
TCGA Data PortalMTCH2 
Broad Tumor PortalMTCH2
OASIS PortalMTCH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTCH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTCH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MTCH2
DgiDB (Drug Gene Interaction Database)MTCH2
DoCM (Curated mutations)MTCH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTCH2 (select a term)
intoGenMTCH2
Cancer3DMTCH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613221   
Orphanet
MedgenMTCH2
Genetic Testing Registry MTCH2
NextProtQ9Y6C9 [Medical]
TSGene23788
GENETestsMTCH2
Target ValidationMTCH2
Huge Navigator MTCH2 [HugePedia]
snp3D : Map Gene to Disease23788
BioCentury BCIQMTCH2
ClinGenMTCH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23788
Chemical/Pharm GKB GenePA134951260
Clinical trialMTCH2
Miscellaneous
canSAR (ICR)MTCH2 (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTCH2
EVEXMTCH2
GoPubMedMTCH2
iHOPMTCH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:31:24 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.