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MTERF1 (mitochondrial transcription termination factor 1)

Identity

Alias_namesMTERF
mitochondrial transcription termination factor
Other alias
HGNC (Hugo) MTERF1
LocusID (NCBI) 7978
Atlas_Id 54038
Location 7q21.2  [Link to chromosome band 7q21]
Location_base_pair Starts at 91872876 and ends at 91880720 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTERF1 (7q21.2) / ELOVL5 (6p12.1)MTERF1 (7q21.2) / PHTF2 (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;7)(q11;q21) MTERF1/PHTF2


External links

Nomenclature
HGNC (Hugo)MTERF1   21463
Cards
Entrez_Gene (NCBI)MTERF1  7978  mitochondrial transcription termination factor 1
AliasesMTERF
GeneCards (Weizmann)MTERF1
Ensembl hg19 (Hinxton)ENSG00000127989 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127989 [Gene_View]  ENSG00000127989 [Sequence]  chr7:91872876-91880720 [Contig_View]  MTERF1 [Vega]
ICGC DataPortalENSG00000127989
TCGA cBioPortalMTERF1
AceView (NCBI)MTERF1
Genatlas (Paris)MTERF1
WikiGenes7978
SOURCE (Princeton)MTERF1
Genetics Home Reference (NIH)MTERF1
Genomic and cartography
GoldenPath hg38 (UCSC)MTERF1  -     chr7:91872876-91880720 -  7q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTERF1  -     7q21.2   [Description]    (hg19-Feb_2009)
EnsemblMTERF1 - 7q21.2 [CytoView hg19]  MTERF1 - 7q21.2 [CytoView hg38]
Mapping of homologs : NCBIMTERF1 [Mapview hg19]  MTERF1 [Mapview hg38]
OMIM602318   
Gene and transcription
Genbank (Entrez)AK222730 AK298469 AK313641 AL832861 BC000965
RefSeq transcript (Entrez)NM_001301134 NM_001301135 NM_006980
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTERF1
Cluster EST : UnigeneHs.532216 [ NCBI ]
CGAP (NCI)Hs.532216
Alternative Splicing GalleryENSG00000127989
Gene ExpressionMTERF1 [ NCBI-GEO ]   MTERF1 [ EBI - ARRAY_EXPRESS ]   MTERF1 [ SEEK ]   MTERF1 [ MEM ]
Gene Expression Viewer (FireBrowse)MTERF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7978
GTEX Portal (Tissue expression)MTERF1
Human Protein AtlasENSG00000127989-MTERF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99551   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99551  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99551
Splice isoforms : SwissVarQ99551
PhosPhoSitePlusQ99551
Domains : Interpro (EBI)MTERF    MTERF_sf   
Domain families : Pfam (Sanger)mTERF (PF02536)   
Domain families : Pfam (NCBI)pfam02536   
Domain families : Smart (EMBL)Mterf (SM00733)  
Conserved Domain (NCBI)MTERF1
DMDM Disease mutations7978
Blocks (Seattle)MTERF1
PDB (SRS)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
PDB (PDBSum)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
PDB (IMB)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
PDB (RSDB)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
Structural Biology KnowledgeBase3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
SCOP (Structural Classification of Proteins)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
CATH (Classification of proteins structures)3MVA    3MVB    3N6S    3N7Q    5CKY    5CO0    5CRJ    5CRK   
SuperfamilyQ99551
Human Protein Atlas [tissue]ENSG00000127989-MTERF1 [tissue]
Peptide AtlasQ99551
HPRD08373
IPIIPI00016095   IPI00925256   IPI00924595   IPI00927877   IPI00927635   
Protein Interaction databases
DIP (DOE-UCLA)Q99551
IntAct (EBI)Q99551
FunCoupENSG00000127989
BioGRIDMTERF1
STRING (EMBL)MTERF1
ZODIACMTERF1
Ontologies - Pathways
QuickGOQ99551
Ontology : AmiGOdouble-stranded DNA binding  RNA binding  protein binding  mitochondrion  mitochondrial matrix  cytosol  DNA-templated transcription, termination  regulation of transcription, DNA-templated  termination of mitochondrial transcription  termination of mitochondrial transcription  termination of mitochondrial transcription  mitochondrion organization  DNA geometric change  mitochondrial nucleoid  
Ontology : EGO-EBIdouble-stranded DNA binding  RNA binding  protein binding  mitochondrion  mitochondrial matrix  cytosol  DNA-templated transcription, termination  regulation of transcription, DNA-templated  termination of mitochondrial transcription  termination of mitochondrial transcription  termination of mitochondrial transcription  mitochondrion organization  DNA geometric change  mitochondrial nucleoid  
NDEx NetworkMTERF1
Atlas of Cancer Signalling NetworkMTERF1
Wikipedia pathwaysMTERF1
Orthology - Evolution
OrthoDB7978
GeneTree (enSembl)ENSG00000127989
Phylogenetic Trees/Animal Genes : TreeFamMTERF1
HOVERGENQ99551
HOGENOMQ99551
Homologs : HomoloGeneMTERF1
Homology/Alignments : Family Browser (UCSC)MTERF1
Gene fusions - Rearrangements
Fusion : MitelmanMTERF1/PHTF2 [7q21.2/7q11.23]  
Fusion : QuiverMTERF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTERF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTERF1
dbVarMTERF1
ClinVarMTERF1
1000_GenomesMTERF1 
Exome Variant ServerMTERF1
ExAC (Exome Aggregation Consortium)ENSG00000127989
GNOMAD BrowserENSG00000127989
Varsome BrowserMTERF1
Genetic variants : HAPMAP7978
Genomic Variants (DGV)MTERF1 [DGVbeta]
DECIPHERMTERF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTERF1 
Mutations
ICGC Data PortalMTERF1 
TCGA Data PortalMTERF1 
Broad Tumor PortalMTERF1
OASIS PortalMTERF1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMTERF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MTERF1
DgiDB (Drug Gene Interaction Database)MTERF1
DoCM (Curated mutations)MTERF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTERF1 (select a term)
intoGenMTERF1
Cancer3DMTERF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602318   
Orphanet
DisGeNETMTERF1
MedgenMTERF1
Genetic Testing Registry MTERF1
NextProtQ99551 [Medical]
TSGene7978
GENETestsMTERF1
Target ValidationMTERF1
Huge Navigator MTERF1 [HugePedia]
snp3D : Map Gene to Disease7978
BioCentury BCIQMTERF1
ClinGenMTERF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7978
Chemical/Pharm GKB GenePA142671308
Clinical trialMTERF1
Miscellaneous
canSAR (ICR)MTERF1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTERF1
EVEXMTERF1
GoPubMedMTERF1
iHOPMTERF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:24:08 CET 2018

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