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MTERF4 (mitochondrial transcription termination factor 4)

Identity

Alias_namesMTERFD2
MTERF domain containing 2
Alias_symbol (synonym)MGC61716
Other alias
HGNC (Hugo) MTERF4
LocusID (NCBI) 130916
Atlas_Id 70539
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 241095566 and ends at 241102332 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKRD37 (4q35.1) / MTERF4 (2q37.3)MTERF4 (2q37.3) / FGFR1 (8p11.23)MTERF4 (2q37.3) / HDLBP (2q37.3)
MTERF4 (2q37.3) / TPM3 (1q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTERF4   28785
Cards
Entrez_Gene (NCBI)MTERF4  130916  mitochondrial transcription termination factor 4
AliasesMTERFD2
GeneCards (Weizmann)MTERF4
Ensembl hg19 (Hinxton)ENSG00000122085 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122085 [Gene_View]  chr2:241095566-241102332 [Contig_View]  MTERF4 [Vega]
ICGC DataPortalENSG00000122085
TCGA cBioPortalMTERF4
AceView (NCBI)MTERF4
Genatlas (Paris)MTERF4
WikiGenes130916
SOURCE (Princeton)MTERF4
Genetics Home Reference (NIH)MTERF4
Genomic and cartography
GoldenPath hg38 (UCSC)MTERF4  -     chr2:241095566-241102332 -  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTERF4  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblMTERF4 - 2q37.3 [CytoView hg19]  MTERF4 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBIMTERF4 [Mapview hg19]  MTERF4 [Mapview hg38]
OMIM615393   
Gene and transcription
Genbank (Entrez)AA907534 AF161359 AK025374 AK055474 AK093695
RefSeq transcript (Entrez)NM_001330179 NM_001330180 NM_182501
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTERF4
Cluster EST : UnigeneHs.159556 [ NCBI ]
CGAP (NCI)Hs.159556
Alternative Splicing GalleryENSG00000122085
Gene ExpressionMTERF4 [ NCBI-GEO ]   MTERF4 [ EBI - ARRAY_EXPRESS ]   MTERF4 [ SEEK ]   MTERF4 [ MEM ]
Gene Expression Viewer (FireBrowse)MTERF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130916
GTEX Portal (Tissue expression)MTERF4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z6M4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z6M4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z6M4
Splice isoforms : SwissVarQ7Z6M4
PhosPhoSitePlusQ7Z6M4
Domains : Interpro (EBI)MTERF   
Domain families : Pfam (Sanger)mTERF (PF02536)   
Domain families : Pfam (NCBI)pfam02536   
Domain families : Smart (EMBL)Mterf (SM00733)  
Conserved Domain (NCBI)MTERF4
DMDM Disease mutations130916
Blocks (Seattle)MTERF4
PDB (SRS)4FP9    4FZV   
PDB (PDBSum)4FP9    4FZV   
PDB (IMB)4FP9    4FZV   
PDB (RSDB)4FP9    4FZV   
Structural Biology KnowledgeBase4FP9    4FZV   
SCOP (Structural Classification of Proteins)4FP9    4FZV   
CATH (Classification of proteins structures)4FP9    4FZV   
SuperfamilyQ7Z6M4
Human Protein AtlasENSG00000122085
Peptide AtlasQ7Z6M4
HPRD14699
IPIIPI00376346   IPI00894278   IPI00893913   IPI00894053   IPI00893601   IPI00893730   IPI00893357   IPI00893340   IPI00893053   IPI00893206   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z6M4
IntAct (EBI)Q7Z6M4
FunCoupENSG00000122085
BioGRIDMTERF4
STRING (EMBL)MTERF4
ZODIACMTERF4
Ontologies - Pathways
QuickGOQ7Z6M4
Ontology : AmiGOdouble-stranded DNA binding  single-stranded RNA binding  protein binding  mitochondrion  mitochondrial matrix  mitochondrial large ribosomal subunit  cytosol  regulation of transcription, DNA-templated  transcription from mitochondrial promoter  protein targeting to mitochondrion  heart development  RNA splicing  rRNA binding  rRNA methylation  developmental process  ribosome assembly  camera-type eye development  
Ontology : EGO-EBIdouble-stranded DNA binding  single-stranded RNA binding  protein binding  mitochondrion  mitochondrial matrix  mitochondrial large ribosomal subunit  cytosol  regulation of transcription, DNA-templated  transcription from mitochondrial promoter  protein targeting to mitochondrion  heart development  RNA splicing  rRNA binding  rRNA methylation  developmental process  ribosome assembly  camera-type eye development  
NDEx NetworkMTERF4
Atlas of Cancer Signalling NetworkMTERF4
Wikipedia pathwaysMTERF4
Orthology - Evolution
OrthoDB130916
GeneTree (enSembl)ENSG00000122085
Phylogenetic Trees/Animal Genes : TreeFamMTERF4
HOVERGENQ7Z6M4
HOGENOMQ7Z6M4
Homologs : HomoloGeneMTERF4
Homology/Alignments : Family Browser (UCSC)MTERF4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTERF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTERF4
dbVarMTERF4
ClinVarMTERF4
1000_GenomesMTERF4 
Exome Variant ServerMTERF4
ExAC (Exome Aggregation Consortium)MTERF4 (select the gene name)
Genetic variants : HAPMAP130916
Genomic Variants (DGV)MTERF4 [DGVbeta]
DECIPHERMTERF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTERF4 
Mutations
ICGC Data PortalMTERF4 
TCGA Data PortalMTERF4 
Broad Tumor PortalMTERF4
OASIS PortalMTERF4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMTERF4
BioMutasearch MTERF4
DgiDB (Drug Gene Interaction Database)MTERF4
DoCM (Curated mutations)MTERF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTERF4 (select a term)
intoGenMTERF4
Cancer3DMTERF4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615393   
Orphanet
MedgenMTERF4
Genetic Testing Registry MTERF4
NextProtQ7Z6M4 [Medical]
TSGene130916
GENETestsMTERF4
Target ValidationMTERF4
Huge Navigator MTERF4 [HugePedia]
snp3D : Map Gene to Disease130916
BioCentury BCIQMTERF4
ClinGenMTERF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130916
Chemical/Pharm GKB GenePA142671310
Clinical trialMTERF4
Miscellaneous
canSAR (ICR)MTERF4 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTERF4
EVEXMTERF4
GoPubMedMTERF4
iHOPMTERF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:31:25 CEST 2017

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