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MTFR2 (mitochondrial fission regulator 2)

Identity

Alias_namesDUFD1
FAM54A
DUF729 domain containing 1
family with sequence similarity 54, member A
Other alias
HGNC (Hugo) MTFR2
LocusID (NCBI) 113115
Atlas_Id 70544
Location 6q23.3  [Link to chromosome band 6q23]
Location_base_pair Starts at 136231030 and ends at 136250335 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTFR2   21115
Cards
Entrez_Gene (NCBI)MTFR2  113115  mitochondrial fission regulator 2
AliasesDUFD1; FAM54A
GeneCards (Weizmann)MTFR2
Ensembl hg19 (Hinxton)ENSG00000146410 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146410 [Gene_View]  ENSG00000146410 [Sequence]  chr6:136231030-136250335 [Contig_View]  MTFR2 [Vega]
ICGC DataPortalENSG00000146410
TCGA cBioPortalMTFR2
AceView (NCBI)MTFR2
Genatlas (Paris)MTFR2
WikiGenes113115
SOURCE (Princeton)MTFR2
Genetics Home Reference (NIH)MTFR2
Genomic and cartography
GoldenPath hg38 (UCSC)MTFR2  -     chr6:136231030-136250335 -  6q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTFR2  -     6q23.3   [Description]    (hg19-Feb_2009)
EnsemblMTFR2 - 6q23.3 [CytoView hg19]  MTFR2 - 6q23.3 [CytoView hg38]
Mapping of homologs : NCBIMTFR2 [Mapview hg19]  MTFR2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA830483 AK125758 AK292303 BC011716 BC063688
RefSeq transcript (Entrez)NM_001099286 NM_001318738 NM_138419
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTFR2
Cluster EST : UnigeneHs.121536 [ NCBI ]
CGAP (NCI)Hs.121536
Alternative Splicing GalleryENSG00000146410
Gene ExpressionMTFR2 [ NCBI-GEO ]   MTFR2 [ EBI - ARRAY_EXPRESS ]   MTFR2 [ SEEK ]   MTFR2 [ MEM ]
Gene Expression Viewer (FireBrowse)MTFR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113115
GTEX Portal (Tissue expression)MTFR2
Human Protein AtlasENSG00000146410-MTFR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P444   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P444  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P444
Splice isoforms : SwissVarQ6P444
PhosPhoSitePlusQ6P444
Domains : Interpro (EBI)Mtfr1   
Domain families : Pfam (Sanger)Mito_fiss_reg (PF05308)   
Domain families : Pfam (NCBI)pfam05308   
Conserved Domain (NCBI)MTFR2
DMDM Disease mutations113115
Blocks (Seattle)MTFR2
SuperfamilyQ6P444
Human Protein Atlas [tissue]ENSG00000146410-MTFR2 [tissue]
Peptide AtlasQ6P444
HPRD16884
IPIIPI00017979   IPI00984624   IPI00985263   IPI00974499   
Protein Interaction databases
DIP (DOE-UCLA)Q6P444
IntAct (EBI)Q6P444
FunCoupENSG00000146410
BioGRIDMTFR2
STRING (EMBL)MTFR2
ZODIACMTFR2
Ontologies - Pathways
QuickGOQ6P444
Ontology : AmiGOmitochondrial fission  mitochondrial fission  protein binding  mitochondrion  mitochondrion  mitochondrion organization  aerobic respiration  aerobic respiration  
Ontology : EGO-EBImitochondrial fission  mitochondrial fission  protein binding  mitochondrion  mitochondrion  mitochondrion organization  aerobic respiration  aerobic respiration  
NDEx NetworkMTFR2
Atlas of Cancer Signalling NetworkMTFR2
Wikipedia pathwaysMTFR2
Orthology - Evolution
OrthoDB113115
GeneTree (enSembl)ENSG00000146410
Phylogenetic Trees/Animal Genes : TreeFamMTFR2
HOVERGENQ6P444
HOGENOMQ6P444
Homologs : HomoloGeneMTFR2
Homology/Alignments : Family Browser (UCSC)MTFR2
Gene fusions - Rearrangements
Fusion : QuiverMTFR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTFR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTFR2
dbVarMTFR2
ClinVarMTFR2
1000_GenomesMTFR2 
Exome Variant ServerMTFR2
ExAC (Exome Aggregation Consortium)ENSG00000146410
GNOMAD BrowserENSG00000146410
Varsome BrowserMTFR2
Genetic variants : HAPMAP113115
Genomic Variants (DGV)MTFR2 [DGVbeta]
DECIPHERMTFR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTFR2 
Mutations
ICGC Data PortalMTFR2 
TCGA Data PortalMTFR2 
Broad Tumor PortalMTFR2
OASIS PortalMTFR2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMTFR2
BioMutasearch MTFR2
DgiDB (Drug Gene Interaction Database)MTFR2
DoCM (Curated mutations)MTFR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTFR2 (select a term)
intoGenMTFR2
Cancer3DMTFR2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMTFR2
MedgenMTFR2
Genetic Testing Registry MTFR2
NextProtQ6P444 [Medical]
TSGene113115
GENETestsMTFR2
Target ValidationMTFR2
Huge Navigator MTFR2 [HugePedia]
snp3D : Map Gene to Disease113115
BioCentury BCIQMTFR2
ClinGenMTFR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113115
Chemical/Pharm GKB GenePA134871105
Clinical trialMTFR2
Miscellaneous
canSAR (ICR)MTFR2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTFR2
EVEXMTFR2
GoPubMedMTFR2
iHOPMTFR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:18:53 CEST 2018

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