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MTL5 (metallothionein-like 5, testis-specific (tesmin))

Identity

Other aliasCXCDC2
MTLT
TESMIN
HGNC (Hugo) MTL5
LocusID (NCBI) 9633
Atlas_Id 70553
Location 11q13.3  [Link to chromosome band 11q13]
Location_base_pair Starts at 68503600 and ends at 68518988 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KMT5B (11q13.2) / MTL5 (11q13.3)MTL5 (11q13.3) / HIPK3 (11p13)MTL5 (11q13.3) / HOOK1 (1p32.1)
MTL5 (11q13.3) / PPFIA1 (11q13.3)MTL5 (11q13.3) / SART1 (11q13.1)NADSYN1 (11q13.4) / MTL5 (11q13.3)
PPP6R3 (11q13.2) / MTL5 (11q13.3)SS18 (18q11.2) / MTL5 (11q13.3)MTL5 HIPK3
MTL5 PPFIA1MTL5 SART1PPP6R3 MTL5
SUV420H1 MTL5

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTL5   7446
Cards
Entrez_Gene (NCBI)MTL5  9633  metallothionein-like 5, testis-specific (tesmin)
AliasesCXCDC2; MTLT; TESMIN
GeneCards (Weizmann)MTL5
Ensembl hg19 (Hinxton)ENSG00000132749 [Gene_View]  chr11:68503600-68518988 [Contig_View]  MTL5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132749 [Gene_View]  chr11:68503600-68518988 [Contig_View]  MTL5 [Vega]
ICGC DataPortalENSG00000132749
TCGA cBioPortalMTL5
AceView (NCBI)MTL5
Genatlas (Paris)MTL5
WikiGenes9633
SOURCE (Princeton)MTL5
Genetics Home Reference (NIH)MTL5
Genomic and cartography
GoldenPath hg19 (UCSC)MTL5  -     chr11:68503600-68518988 -  11q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MTL5  -     11q13.3   [Description]    (hg38-Dec_2013)
EnsemblMTL5 - 11q13.3 [CytoView hg19]  MTL5 - 11q13.3 [CytoView hg38]
Mapping of homologs : NCBIMTL5 [Mapview hg19]  MTL5 [Mapview hg38]
OMIM604374   
Gene and transcription
Genbank (Entrez)AK074817 AK128308 AK292358 AW293246 BC027593
RefSeq transcript (Entrez)NM_001039656 NM_004923
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)MTL5
Cluster EST : UnigeneHs.145932 [ NCBI ]
CGAP (NCI)Hs.145932
Alternative Splicing GalleryENSG00000132749
Gene ExpressionMTL5 [ NCBI-GEO ]   MTL5 [ EBI - ARRAY_EXPRESS ]   MTL5 [ SEEK ]   MTL5 [ MEM ]
Gene Expression Viewer (FireBrowse)MTL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9633
GTEX Portal (Tissue expression)MTL5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4I5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4I5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4I5
Splice isoforms : SwissVarQ9Y4I5
PhosPhoSitePlusQ9Y4I5
Domaine pattern : Prosite (Expaxy)CRC (PS51634)   
Domains : Interpro (EBI)CRC    Lin-54_fam   
Domain families : Pfam (Sanger)TCR (PF03638)   
Domain families : Pfam (NCBI)pfam03638   
Conserved Domain (NCBI)MTL5
DMDM Disease mutations9633
Blocks (Seattle)MTL5
SuperfamilyQ9Y4I5
Human Protein AtlasENSG00000132749
Peptide AtlasQ9Y4I5
HPRD09186
IPIIPI00007395   IPI00738914   IPI00903174   IPI00448599   IPI00979743   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4I5
IntAct (EBI)Q9Y4I5
FunCoupENSG00000132749
BioGRIDMTL5
STRING (EMBL)MTL5
ZODIACMTL5
Ontologies - Pathways
QuickGOQ9Y4I5
Ontology : AmiGOnucleus  cytoplasm  cellular metal ion homeostasis  multicellular organismal development  spermatogenesis  response to metal ion  cell differentiation  metal ion binding  
Ontology : EGO-EBInucleus  cytoplasm  cellular metal ion homeostasis  multicellular organismal development  spermatogenesis  response to metal ion  cell differentiation  metal ion binding  
NDEx NetworkMTL5
Atlas of Cancer Signalling NetworkMTL5
Wikipedia pathwaysMTL5
Orthology - Evolution
OrthoDB9633
GeneTree (enSembl)ENSG00000132749
Phylogenetic Trees/Animal Genes : TreeFamMTL5
HOVERGENQ9Y4I5
HOGENOMQ9Y4I5
Homologs : HomoloGeneMTL5
Homology/Alignments : Family Browser (UCSC)MTL5
Gene fusions - Rearrangements
Fusion: TCGAMTL5 HIPK3
Fusion: TCGAMTL5 PPFIA1
Fusion: TCGAMTL5 SART1
Fusion: TCGAPPP6R3 MTL5
Fusion: TCGASUV420H1 MTL5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTL5
dbVarMTL5
ClinVarMTL5
1000_GenomesMTL5 
Exome Variant ServerMTL5
ExAC (Exome Aggregation Consortium)MTL5 (select the gene name)
Genetic variants : HAPMAP9633
Genomic Variants (DGV)MTL5 [DGVbeta]
DECIPHER (Syndromes)11:68503600-68518988  ENSG00000132749
CONAN: Copy Number AnalysisMTL5 
Mutations
ICGC Data PortalMTL5 
TCGA Data PortalMTL5 
Broad Tumor PortalMTL5
OASIS PortalMTL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MTL5
DgiDB (Drug Gene Interaction Database)MTL5
DoCM (Curated mutations)MTL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTL5 (select a term)
intoGenMTL5
Cancer3DMTL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604374   
Orphanet
MedgenMTL5
Genetic Testing Registry MTL5
NextProtQ9Y4I5 [Medical]
TSGene9633
GENETestsMTL5
Huge Navigator MTL5 [HugePedia]
snp3D : Map Gene to Disease9633
BioCentury BCIQMTL5
ClinGenMTL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9633
Chemical/Pharm GKB GenePA31249
Clinical trialMTL5
Miscellaneous
canSAR (ICR)MTL5 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTL5
EVEXMTL5
GoPubMedMTL5
iHOPMTL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:34:04 CET 2017

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