Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MTLN (mitoregulin)

Identity

Alias (NCBI)LEMP
LINC00116
MOXI
MPM
NCRNA00116
SMIM37
HGNC (Hugo) MTLN
LocusID (NCBI) 205251
Atlas_Id 80372
Location 2q13  [Link to chromosome band 2q13]
Location_base_pair Starts at 110211529 and ends at 110245420 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

 

Nomenclature
HGNC (Hugo)MTLN   27339
Cards
Entrez_Gene (NCBI)MTLN    mitoregulin
AliasesLEMP; LINC00116; MOXI; MPM; 
NCRNA00116; SMIM37
GeneCards (Weizmann)MTLN
Ensembl hg19 (Hinxton)ENSG00000175701 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175701 [Gene_View]  ENSG00000175701 [Sequence]  chr2:110211529-110245420 [Contig_View]  MTLN [Vega]
ICGC DataPortalENSG00000175701
TCGA cBioPortalMTLN
AceView (NCBI)MTLN
Genatlas (Paris)MTLN
SOURCE (Princeton)MTLN
Genetics Home Reference (NIH)MTLN
Genomic and cartography
GoldenPath hg38 (UCSC)MTLN  -     chr2:110211529-110245420 -  2q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTLN  -     2q13   [Description]    (hg19-Feb_2009)
GoldenPathMTLN - 2q13 [CytoView hg19]  MTLN - 2q13 [CytoView hg38]
ImmunoBaseENSG00000175701
Genome Data Viewer NCBIMTLN [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF504645 BC031315 BC064430 BC133660 H50192
RefSeq transcript (Entrez)NM_001355251 NM_001384134
Consensus coding sequences : CCDS (NCBI)MTLN
Gene ExpressionMTLN [ NCBI-GEO ]   MTLN [ EBI - ARRAY_EXPRESS ]   MTLN [ SEEK ]   MTLN [ MEM ]
Gene Expression Viewer (FireBrowse)MTLN [ Firebrowse - Broad ]
GenevisibleExpression of MTLN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)205251
GTEX Portal (Tissue expression)MTLN
Human Protein AtlasENSG00000175701-MTLN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NCU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NCU8
PhosPhoSitePlusQ8NCU8
Domains : Interpro (EBI)Mtln   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MTLN
SuperfamilyQ8NCU8
AlphaFold pdb e-kbQ8NCU8   
Human Protein Atlas [tissue]ENSG00000175701-MTLN [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8NCU8
IntAct (EBI)Q8NCU8
BioGRIDMTLN
STRING (EMBL)MTLN
ZODIACMTLN
Ontologies - Pathways
QuickGOQ8NCU8
Ontology : AmiGOprotein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  fatty acid beta-oxidation  positive regulation of mitochondrial membrane potential  positive regulation of mitochondrial membrane potential  integral component of mitochondrial inner membrane  integral component of mitochondrial inner membrane  positive regulation of protein-containing complex assembly  positive regulation of fatty acid beta-oxidation  cellular lipid metabolic process  cellular respiration  striated muscle cell differentiation  positive regulation of sequestering of calcium ion  positive regulation of sequestering of calcium ion  triglyceride homeostasis  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrion  mitochondrial inner membrane  fatty acid beta-oxidation  positive regulation of mitochondrial membrane potential  positive regulation of mitochondrial membrane potential  integral component of mitochondrial inner membrane  integral component of mitochondrial inner membrane  positive regulation of protein-containing complex assembly  positive regulation of fatty acid beta-oxidation  cellular lipid metabolic process  cellular respiration  striated muscle cell differentiation  positive regulation of sequestering of calcium ion  positive regulation of sequestering of calcium ion  triglyceride homeostasis  
NDEx NetworkMTLN
Atlas of Cancer Signalling NetworkMTLN
Wikipedia pathwaysMTLN
Orthology - Evolution
OrthoDB205251
GeneTree (enSembl)ENSG00000175701
Phylogenetic Trees/Animal Genes : TreeFamMTLN
Homologs : HomoloGeneMTLN
Homology/Alignments : Family Browser (UCSC)MTLN
Gene fusions - Rearrangements
Fusion : QuiverMTLN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTLN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTLN
dbVarMTLN
ClinVarMTLN
MonarchMTLN
1000_GenomesMTLN 
Exome Variant ServerMTLN
GNOMAD BrowserENSG00000175701
Varsome BrowserMTLN
ACMGMTLN variants
VarityQ8NCU8
Genomic Variants (DGV)MTLN [DGVbeta]
DECIPHERMTLN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTLN 
Mutations
ICGC Data PortalMTLN 
TCGA Data PortalMTLN 
Broad Tumor PortalMTLN
OASIS PortalMTLN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTLN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMTLN
Mutations and Diseases : HGMDMTLN
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMTLN
DgiDB (Drug Gene Interaction Database)MTLN
DoCM (Curated mutations)MTLN
CIViC (Clinical Interpretations of Variants in Cancer)MTLN
Cancer3DMTLN
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMTLN
MedgenMTLN
Genetic Testing Registry MTLN
NextProtQ8NCU8 [Medical]
GENETestsMTLN
Target ValidationMTLN
Huge Navigator MTLN [HugePedia]
ClinGenMTLN
Clinical trials, drugs, therapy
MyCancerGenomeMTLN
Protein Interactions : CTDMTLN
Pharm GKB GenePA164723669
PharosQ8NCU8
Clinical trialMTLN
Miscellaneous
canSAR (ICR)MTLN
HarmonizomeMTLN
DataMed IndexMTLN
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMTLN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:11:59 CEST 2021

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