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MTNR1A (melatonin receptor 1A)

Identity

Alias_symbol (synonym)MEL-1A-R
Other aliasMT1
HGNC (Hugo) MTNR1A
LocusID (NCBI) 4543
Atlas_Id 45706
Location 4q35.2  [Link to chromosome band 4q35]
Location_base_pair Starts at 186533655 and ends at 186555567 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTNR1A   7463
Cards
Entrez_Gene (NCBI)MTNR1A  4543  melatonin receptor 1A
AliasesMEL-1A-R; MT1
GeneCards (Weizmann)MTNR1A
Ensembl hg19 (Hinxton)ENSG00000168412 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168412 [Gene_View]  chr4:186533655-186555567 [Contig_View]  MTNR1A [Vega]
ICGC DataPortalENSG00000168412
TCGA cBioPortalMTNR1A
AceView (NCBI)MTNR1A
Genatlas (Paris)MTNR1A
WikiGenes4543
SOURCE (Princeton)MTNR1A
Genetics Home Reference (NIH)MTNR1A
Genomic and cartography
GoldenPath hg38 (UCSC)MTNR1A  -     chr4:186533655-186555567 -  4q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTNR1A  -     4q35.2   [Description]    (hg19-Feb_2009)
EnsemblMTNR1A - 4q35.2 [CytoView hg19]  MTNR1A - 4q35.2 [CytoView hg38]
Mapping of homologs : NCBIMTNR1A [Mapview hg19]  MTNR1A [Mapview hg38]
OMIM600665   
Gene and transcription
Genbank (Entrez)AF435588 BC074946 BC074947 BC113816 BC126297
RefSeq transcript (Entrez)NM_005958
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTNR1A
Cluster EST : UnigeneHs.243467 [ NCBI ]
CGAP (NCI)Hs.243467
Alternative Splicing GalleryENSG00000168412
Gene ExpressionMTNR1A [ NCBI-GEO ]   MTNR1A [ EBI - ARRAY_EXPRESS ]   MTNR1A [ SEEK ]   MTNR1A [ MEM ]
Gene Expression Viewer (FireBrowse)MTNR1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4543
GTEX Portal (Tissue expression)MTNR1A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48039   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48039  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48039
Splice isoforms : SwissVarP48039
PhosPhoSitePlusP48039
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Mel_1A_rcpt    Melatonin_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)MTNR1A
DMDM Disease mutations4543
Blocks (Seattle)MTNR1A
SuperfamilyP48039
Human Protein AtlasENSG00000168412
Peptide AtlasP48039
HPRD02812
IPIIPI00007600   IPI00967379   
Protein Interaction databases
DIP (DOE-UCLA)P48039
IntAct (EBI)P48039
FunCoupENSG00000168412
BioGRIDMTNR1A
STRING (EMBL)MTNR1A
ZODIACMTNR1A
Ontologies - Pathways
QuickGOP48039
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  mating behavior  circadian rhythm  melatonin receptor activity  positive regulation of cGMP biosynthetic process  hormone binding  receptor complex  organic cyclic compound binding  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  mating behavior  circadian rhythm  melatonin receptor activity  positive regulation of cGMP biosynthetic process  hormone binding  receptor complex  organic cyclic compound binding  
Pathways : KEGGNeuroactive ligand-receptor interaction    Circadian entrainment   
NDEx NetworkMTNR1A
Atlas of Cancer Signalling NetworkMTNR1A
Wikipedia pathwaysMTNR1A
Orthology - Evolution
OrthoDB4543
GeneTree (enSembl)ENSG00000168412
Phylogenetic Trees/Animal Genes : TreeFamMTNR1A
HOVERGENP48039
HOGENOMP48039
Homologs : HomoloGeneMTNR1A
Homology/Alignments : Family Browser (UCSC)MTNR1A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTNR1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTNR1A
dbVarMTNR1A
ClinVarMTNR1A
1000_GenomesMTNR1A 
Exome Variant ServerMTNR1A
ExAC (Exome Aggregation Consortium)MTNR1A (select the gene name)
Genetic variants : HAPMAP4543
Genomic Variants (DGV)MTNR1A [DGVbeta]
DECIPHERMTNR1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTNR1A 
Mutations
ICGC Data PortalMTNR1A 
TCGA Data PortalMTNR1A 
Broad Tumor PortalMTNR1A
OASIS PortalMTNR1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTNR1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTNR1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MTNR1A
DgiDB (Drug Gene Interaction Database)MTNR1A
DoCM (Curated mutations)MTNR1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTNR1A (select a term)
intoGenMTNR1A
Cancer3DMTNR1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600665   
Orphanet
MedgenMTNR1A
Genetic Testing Registry MTNR1A
NextProtP48039 [Medical]
TSGene4543
GENETestsMTNR1A
Target ValidationMTNR1A
Huge Navigator MTNR1A [HugePedia]
snp3D : Map Gene to Disease4543
BioCentury BCIQMTNR1A
ClinGenMTNR1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4543
Chemical/Pharm GKB GenePA31267
Clinical trialMTNR1A
Miscellaneous
canSAR (ICR)MTNR1A (select the gene name)
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTNR1A
EVEXMTNR1A
GoPubMedMTNR1A
iHOPMTNR1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:20:50 CEST 2017

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