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MTPAP (mitochondrial poly(A) polymerase)

Identity

Alias_namesPAPD1
PAP associated domain containing 1
Alias_symbol (synonym)FLJ10486
mtPAP
SPAX4
Other alias
HGNC (Hugo) MTPAP
LocusID (NCBI) 55149
Atlas_Id 54954
Location 10p11.23  [Link to chromosome band 10p11]
Location_base_pair Starts at 30309801 and ends at 30349338 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MTPAP (10p11.23) / ARHGAP21 (10p12.1)TCF7 (5q31.1) / MTPAP (10p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTPAP   25532
Cards
Entrez_Gene (NCBI)MTPAP  55149  mitochondrial poly(A) polymerase
AliasesPAPD1; SPAX4
GeneCards (Weizmann)MTPAP
Ensembl hg19 (Hinxton)ENSG00000107951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107951 [Gene_View]  chr10:30309801-30349338 [Contig_View]  MTPAP [Vega]
ICGC DataPortalENSG00000107951
TCGA cBioPortalMTPAP
AceView (NCBI)MTPAP
Genatlas (Paris)MTPAP
WikiGenes55149
SOURCE (Princeton)MTPAP
Genetics Home Reference (NIH)MTPAP
Genomic and cartography
GoldenPath hg38 (UCSC)MTPAP  -     chr10:30309801-30349338 -  10p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTPAP  -     10p11.23   [Description]    (hg19-Feb_2009)
EnsemblMTPAP - 10p11.23 [CytoView hg19]  MTPAP - 10p11.23 [CytoView hg38]
Mapping of homologs : NCBIMTPAP [Mapview hg19]  MTPAP [Mapview hg38]
OMIM613669   613672   
Gene and transcription
Genbank (Entrez)AB194709 AK001348 AK022188 AK125211 AY364242
RefSeq transcript (Entrez)NM_018109
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTPAP
Cluster EST : UnigeneHs.173946 [ NCBI ]
CGAP (NCI)Hs.173946
Alternative Splicing GalleryENSG00000107951
Gene ExpressionMTPAP [ NCBI-GEO ]   MTPAP [ EBI - ARRAY_EXPRESS ]   MTPAP [ SEEK ]   MTPAP [ MEM ]
Gene Expression Viewer (FireBrowse)MTPAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55149
GTEX Portal (Tissue expression)MTPAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NVV4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NVV4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NVV4
Splice isoforms : SwissVarQ9NVV4
PhosPhoSitePlusQ9NVV4
Domains : Interpro (EBI)PAP_assoc   
Domain families : Pfam (Sanger)PAP_assoc (PF03828)   
Domain families : Pfam (NCBI)pfam03828   
Conserved Domain (NCBI)MTPAP
DMDM Disease mutations55149
Blocks (Seattle)MTPAP
PDB (SRS)3PQ1   
PDB (PDBSum)3PQ1   
PDB (IMB)3PQ1   
PDB (RSDB)3PQ1   
Structural Biology KnowledgeBase3PQ1   
SCOP (Structural Classification of Proteins)3PQ1   
CATH (Classification of proteins structures)3PQ1   
SuperfamilyQ9NVV4
Human Protein AtlasENSG00000107951
Peptide AtlasQ9NVV4
HPRD15097
IPIIPI00153051   IPI00470416   IPI00884218   IPI00641482   
Protein Interaction databases
DIP (DOE-UCLA)Q9NVV4
IntAct (EBI)Q9NVV4
FunCoupENSG00000107951
BioGRIDMTPAP
STRING (EMBL)MTPAP
ZODIACMTPAP
Ontologies - Pathways
QuickGOQ9NVV4
Ontology : AmiGOmagnesium ion binding  UTP binding  RNA binding  polynucleotide adenylyltransferase activity  protein binding  ATP binding  mitochondrion  transcription, DNA-templated  mRNA polyadenylation  manganese ion binding  identical protein binding  protein homodimerization activity  intracellular membrane-bounded organelle  histone mRNA catabolic process  
Ontology : EGO-EBImagnesium ion binding  UTP binding  RNA binding  polynucleotide adenylyltransferase activity  protein binding  ATP binding  mitochondrion  transcription, DNA-templated  mRNA polyadenylation  manganese ion binding  identical protein binding  protein homodimerization activity  intracellular membrane-bounded organelle  histone mRNA catabolic process  
NDEx NetworkMTPAP
Atlas of Cancer Signalling NetworkMTPAP
Wikipedia pathwaysMTPAP
Orthology - Evolution
OrthoDB55149
GeneTree (enSembl)ENSG00000107951
Phylogenetic Trees/Animal Genes : TreeFamMTPAP
HOVERGENQ9NVV4
HOGENOMQ9NVV4
Homologs : HomoloGeneMTPAP
Homology/Alignments : Family Browser (UCSC)MTPAP
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTPAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTPAP
dbVarMTPAP
ClinVarMTPAP
1000_GenomesMTPAP 
Exome Variant ServerMTPAP
ExAC (Exome Aggregation Consortium)MTPAP (select the gene name)
Genetic variants : HAPMAP55149
Genomic Variants (DGV)MTPAP [DGVbeta]
DECIPHERMTPAP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTPAP 
Mutations
ICGC Data PortalMTPAP 
TCGA Data PortalMTPAP 
Broad Tumor PortalMTPAP
OASIS PortalMTPAP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTPAP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTPAP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MTPAP
DgiDB (Drug Gene Interaction Database)MTPAP
DoCM (Curated mutations)MTPAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTPAP (select a term)
intoGenMTPAP
Cancer3DMTPAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613669    613672   
Orphanet19738   
MedgenMTPAP
Genetic Testing Registry MTPAP
NextProtQ9NVV4 [Medical]
TSGene55149
GENETestsMTPAP
Huge Navigator MTPAP [HugePedia]
snp3D : Map Gene to Disease55149
BioCentury BCIQMTPAP
ClinGenMTPAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55149
Chemical/Pharm GKB GenePA164723192
Clinical trialMTPAP
Miscellaneous
canSAR (ICR)MTPAP (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTPAP
EVEXMTPAP
GoPubMedMTPAP
iHOPMTPAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:27:28 CEST 2017

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