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MTRF1L (mitochondrial translational release factor 1 like)

Identity

Alias_namesmitochondrial translational release factor 1-like
Alias_symbol (synonym)HMRF1L
mtRF1a
Other aliasMRF1L
HGNC (Hugo) MTRF1L
LocusID (NCBI) 54516
Atlas_Id 70565
Location 6q25.2  [Link to chromosome band 6q25]
Location_base_pair Starts at 152987366 and ends at 153002815 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MTRF1L   21051
Cards
Entrez_Gene (NCBI)MTRF1L  54516  mitochondrial translational release factor 1 like
AliasesHMRF1L; MRF1L; mtRF1a
GeneCards (Weizmann)MTRF1L
Ensembl hg19 (Hinxton)ENSG00000112031 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112031 [Gene_View]  ENSG00000112031 [Sequence]  chr6:152987366-153002815 [Contig_View]  MTRF1L [Vega]
ICGC DataPortalENSG00000112031
TCGA cBioPortalMTRF1L
AceView (NCBI)MTRF1L
Genatlas (Paris)MTRF1L
WikiGenes54516
SOURCE (Princeton)MTRF1L
Genetics Home Reference (NIH)MTRF1L
Genomic and cartography
GoldenPath hg38 (UCSC)MTRF1L  -     chr6:152987366-153002815 -  6q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTRF1L  -     6q25.2   [Description]    (hg19-Feb_2009)
EnsemblMTRF1L - 6q25.2 [CytoView hg19]  MTRF1L - 6q25.2 [CytoView hg38]
Mapping of homologs : NCBIMTRF1L [Mapview hg19]  MTRF1L [Mapview hg38]
OMIM613542   
Gene and transcription
Genbank (Entrez)AI434611 AI479199 AI628793 AK001037 AK027684
RefSeq transcript (Entrez)NM_001114184 NM_001301047 NM_001301870 NM_001301871 NM_001301872 NM_019041
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MTRF1L
Cluster EST : UnigeneHs.732132 [ NCBI ]
CGAP (NCI)Hs.732132
Alternative Splicing GalleryENSG00000112031
Gene ExpressionMTRF1L [ NCBI-GEO ]   MTRF1L [ EBI - ARRAY_EXPRESS ]   MTRF1L [ SEEK ]   MTRF1L [ MEM ]
Gene Expression Viewer (FireBrowse)MTRF1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54516
GTEX Portal (Tissue expression)MTRF1L
Human Protein AtlasENSG00000112031-MTRF1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UGC7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UGC7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UGC7
Splice isoforms : SwissVarQ9UGC7
PhosPhoSitePlusQ9UGC7
Domaine pattern : Prosite (Expaxy)RF_PROK_I (PS00745)   
Domains : Interpro (EBI)dsRBD_dom    PCRF    Pep_chain_release_fac_I_II   
Domain families : Pfam (Sanger)PCRF (PF03462)    RF-1 (PF00472)   
Domain families : Pfam (NCBI)pfam03462    pfam00472   
Domain families : Smart (EMBL)PCRF (SM00937)  
Conserved Domain (NCBI)MTRF1L
DMDM Disease mutations54516
Blocks (Seattle)MTRF1L
SuperfamilyQ9UGC7
Human Protein Atlas [tissue]ENSG00000112031-MTRF1L [tissue]
Peptide AtlasQ9UGC7
HPRD17613
IPIIPI00295737   IPI00477207   IPI00890825   IPI00513970   IPI00514863   IPI00514520   
Protein Interaction databases
DIP (DOE-UCLA)Q9UGC7
IntAct (EBI)Q9UGC7
FunCoupENSG00000112031
BioGRIDMTRF1L
STRING (EMBL)MTRF1L
ZODIACMTRF1L
Ontologies - Pathways
QuickGOQ9UGC7
Ontology : AmiGOmitochondrion  mitochondrial matrix  translation release factor activity, codon specific  mitochondrial translational termination  
Ontology : EGO-EBImitochondrion  mitochondrial matrix  translation release factor activity, codon specific  mitochondrial translational termination  
NDEx NetworkMTRF1L
Atlas of Cancer Signalling NetworkMTRF1L
Wikipedia pathwaysMTRF1L
Orthology - Evolution
OrthoDB54516
GeneTree (enSembl)ENSG00000112031
Phylogenetic Trees/Animal Genes : TreeFamMTRF1L
HOVERGENQ9UGC7
HOGENOMQ9UGC7
Homologs : HomoloGeneMTRF1L
Homology/Alignments : Family Browser (UCSC)MTRF1L
Gene fusions - Rearrangements
Fusion : QuiverMTRF1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTRF1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTRF1L
dbVarMTRF1L
ClinVarMTRF1L
1000_GenomesMTRF1L 
Exome Variant ServerMTRF1L
ExAC (Exome Aggregation Consortium)ENSG00000112031
GNOMAD BrowserENSG00000112031
Varsome BrowserMTRF1L
Genetic variants : HAPMAP54516
Genomic Variants (DGV)MTRF1L [DGVbeta]
DECIPHERMTRF1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTRF1L 
Mutations
ICGC Data PortalMTRF1L 
TCGA Data PortalMTRF1L 
Broad Tumor PortalMTRF1L
OASIS PortalMTRF1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTRF1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMTRF1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MTRF1L
DgiDB (Drug Gene Interaction Database)MTRF1L
DoCM (Curated mutations)MTRF1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MTRF1L (select a term)
intoGenMTRF1L
Cancer3DMTRF1L(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613542   
Orphanet
DisGeNETMTRF1L
MedgenMTRF1L
Genetic Testing Registry MTRF1L
NextProtQ9UGC7 [Medical]
TSGene54516
GENETestsMTRF1L
Target ValidationMTRF1L
Huge Navigator MTRF1L [HugePedia]
snp3D : Map Gene to Disease54516
BioCentury BCIQMTRF1L
ClinGenMTRF1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54516
Chemical/Pharm GKB GenePA134870441
Clinical trialMTRF1L
Miscellaneous
canSAR (ICR)MTRF1L (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMTRF1L
EVEXMTRF1L
GoPubMedMTRF1L
iHOPMTRF1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:18:58 CEST 2018

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