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MTSS1 (metastasis suppressor 1)

Identity

Other namesMIM
MIMA
MIMB
HGNC (Hugo) MTSS1
LocusID (NCBI) 9788
Location 8q24.13
Location_base_pair Starts at 125563011 and ends at 125740748 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTSS1   20443
Cards
Entrez_Gene (NCBI)MTSS1  9788  metastasis suppressor 1
GeneCards (Weizmann)MTSS1
Ensembl (Hinxton)ENSG00000170873 [Gene_View]  chr8:125563011-125740748 [Contig_View]  MTSS1 [Vega]
AceView (NCBI)MTSS1
Genatlas (Paris)MTSS1
WikiGenes9788
SOURCE (Princeton)NM_001282971 NM_001282974 NM_014751
Genomic and cartography
GoldenPath (UCSC)MTSS1  -  8q24.13   chr8:125563011-125740748 -  8q24.13   [Description]    (hg19-Feb_2009)
EnsemblMTSS1 - 8q24.13 [CytoView]
Mapping of homologs : NCBIMTSS1 [Mapview]
OMIM608486   
Gene and transcription
Genbank (Entrez)AB007889 AF086645 AF116674 AI041104 AJ710067
RefSeq transcript (Entrez)NM_001282971 NM_001282974 NM_014751
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839136 NW_004929340
Consensus coding sequences : CCDS (NCBI)MTSS1
Cluster EST : UnigeneHs.700429 [ NCBI ]
CGAP (NCI)Hs.700429
Alternative Splicing : Fast-db (Paris)GSHG0029843
Alternative Splicing GalleryENSG00000170873
Gene ExpressionMTSS1 [ NCBI-GEO ]     MTSS1 [ SEEK ]   MTSS1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43312 (Uniprot)
NextProtO43312  [Medical]
With graphics : InterProO43312
Splice isoforms : SwissVarO43312 (Swissvar)
Domaine pattern : Prosite (Expaxy)IMD (PS51338)    WH2 (PS51082)   
Domains : Interpro (EBI)IRSp53/MIM_homology_IMD    MTSS1    WH2_dom   
Related proteins : CluSTrO43312
Domain families : Pfam (Sanger)IMD (PF08397)    WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam08397    pfam02205   
Domain families : Smart (EMBL)WH2 (SM00246)  
DMDM Disease mutations9788
Blocks (Seattle)O43312
PDB (SRS)2D1K   
PDB (PDBSum)2D1K   
PDB (IMB)2D1K   
PDB (RSDB)2D1K   
Human Protein AtlasENSG00000170873
Peptide AtlasO43312
HPRD12243
IPIIPI00983960   IPI00647454   IPI00444645   IPI00922364   IPI00445073   IPI00383355   IPI00152331   IPI00982324   IPI00975593   IPI00976780   IPI00980503   
Protein Interaction databases
DIP (DOE-UCLA)O43312
IntAct (EBI)O43312
FunCoupENSG00000170873
BioGRIDMTSS1
InParanoidO43312
Interologous Interaction database O43312
IntegromeDBMTSS1
STRING (EMBL)MTSS1
Ontologies - Pathways
Ontology : AmiGOruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  cellular component movement  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  cytoskeletal adaptor activity  actin cytoskeleton  SH3 domain binding  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  identical protein binding  filopodium assembly  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Ontology : EGO-EBIruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  cellular component movement  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  cytoskeletal adaptor activity  actin cytoskeleton  SH3 domain binding  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  identical protein binding  filopodium assembly  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
REACTOMEMTSS1
Protein Interaction DatabaseMTSS1
Wikipedia pathwaysMTSS1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MTSS1
SNP (GeneSNP Utah)MTSS1
SNP : HGBaseMTSS1
Genetic variants : HAPMAPMTSS1
1000_GenomesMTSS1 
ICGC programENSG00000170873 
Somatic Mutations in Cancer : COSMICMTSS1 
CONAN: Copy Number AnalysisMTSS1 
Mutations and Diseases : HGMDMTSS1
OMIM608486   
GENETestsMTSS1
Disease Genetic AssociationMTSS1
Huge Navigator MTSS1 [HugePedia]  MTSS1 [HugeCancerGEM]
Genomic VariantsMTSS1  MTSS1 [DGVbeta]
Exome VariantMTSS1
dbVarMTSS1
ClinVarMTSS1
snp3D : Map Gene to Disease9788
General knowledge
Homologs : HomoloGeneMTSS1
Homology/Alignments : Family Browser (UCSC)MTSS1
Phylogenetic Trees/Animal Genes : TreeFamMTSS1
Chemical/Protein Interactions : CTD9788
Chemical/Pharm GKB GenePA134892011
Clinical trialMTSS1
Cancer Resource (Charite)ENSG00000170873
Other databases
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
CoreMineMTSS1
iHOPMTSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:09:12 CEST 2014

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