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MTSS1 (metastasis suppressor 1)

Identity

Other namesMIM
MIMA
MIMB
HGNC (Hugo) MTSS1
LocusID (NCBI) 9788
Location 8q24.13
Location_base_pair Starts at 125563028 and ends at 125740730 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTSS1   20443
Entrez_Gene (NCBI)MTSS1  9788  metastasis suppressor 1
Cards
GeneCards (Weizmann)MTSS1
Ensembl (Hinxton)ENSG00000170873 [Gene_View]  chr8:125563028-125740730 [Contig_View]  MTSS1 [Vega]
AceView (NCBI)MTSS1
Genatlas (Paris)MTSS1
SOURCE (Stanford)NM_014751
Genomic and cartography
GoldenPath (UCSC)MTSS1  -  8q24.13   chr8:125563028-125740730 -  8q24.13   [Description]    (hg19-Feb_2009)
EnsemblMTSS1 - 8q24.13 [CytoView]
Mapping of homologs : NCBIMTSS1 [Mapview]
OMIM608486   
Gene and transcription
Genbank (Entrez)AB007889 AF086645 AF116674 AI041104 AJ710067
RefSeq transcript (SRS)NM_014751
RefSeq transcript (Entrez)NM_014751
RefSeq genomic (SRS)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839136 NW_004078037
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839136 NW_004078037
Consensus coding sequences : CCDS (NCBI)MTSS1
Cluster EST : UnigeneHs.700429 [ SRS ] Hs.700429 [ NCBI ]
CGAP (NCI)Hs.700429
Alternative Splicing : Fast-db (Paris)GSHG0029843
Alternative Splicing GalleryENSG00000170873
Gene ExpressionMTSS1 [ NCBI-GEO ]   MTSS1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43312 (SRS) O43312 (Uniprot)
NextProtO43312
With graphics : InterProO43312
Splice isoforms : SwissVarO43312(Swissvar)
Domaine pattern : Prosite (SRS)IMD (PS51338)    WH2 (PS51082)   
Domaine pattern : Prosite (Expaxy)IMD (PS51338)    WH2 (PS51082)   
Domains : Interpro (SRS)IRSp53/MIM_homology_IMD    WH2_dom   
Domains : Interpro (EBI)IRSp53/MIM_homology_IMD    WH2_dom   
Related proteins : CluSTrO43312
Domain families : Pfam (SRS)IMD (PF08397)    WH2 (PF02205)   
Domain families : Pfam (Sanger)IMD (PF08397)    WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam08397    pfam02205   
Domain families : Smart (EMBL)WH2 (SM00246)  
DMDM9788
Blocks (Seattle)O43312
PDB (SRS)2D1K   
PDB (PDBSum)2D1K   
PDB (IMB)2D1K   
PDB (RSDB)2D1K   
Human Protein AtlasENSG00000170873
HPRD12243
IPIIPI00983960   IPI00647454   IPI00444645   IPI00922364   IPI00445073   IPI00383355   IPI00152331   IPI00982324   IPI00975593   IPI00976780   IPI00980503   
Protein Interaction databases
DIP (DOE-UCLA)O43312
IntAct (EBI)O43312
FunCoupENSG00000170873
REACTOMEMTSS1
Protein Interaction Database9788
BioGRIDMTSS1
InParanoidO43312
Interologous Interaction database O43312
IntegromeDBMTSS1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MTSS1
SNP (GeneSNP Utah)MTSS1
SNP : HGBaseMTSS1
Genetic variants : HAPMAPMTSS1
Somatic Mutations in Cancer : COSMICMTSS1 
CONAN: Copy Number AnalysisMTSS1 
Mutations and Diseases : HGMDMTSS1
OMIM608486   
GENETests608486   
Disease Genetic AssociationMTSS1
Huge Navigator MTSS1 [HugePedia]  MTSS1 [HugeCancerGEM]
Genomic VariantsMTSS1  MTSS1 [DGVbeta]
ClinVarMTSS1
snp3D : Map Gene to Disease9788
General knowledge
Homologs : HomoloGeneMTSS1
Homology/Alignments : Family Browser (UCSC)MTSS1
Phylogenetic Trees/Animal Genes : TreeFamMTSS1
Chemical/Protein Interactions : CTD9788
Chemical/Pharm GKB GenePA134892011
Clinical trialMTSS1
Cancer Resource (Charite)ENSG00000170873
Ontology : AmiGOruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  cellular component movement  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  cytoskeletal adaptor activity  actin cytoskeleton  SH3 domain binding  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  identical protein binding  filopodium assembly  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Ontology : EGO-EBIruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  cellular component movement  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  cytoskeletal adaptor activity  actin cytoskeleton  SH3 domain binding  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  identical protein binding  filopodium assembly  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Other databases
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
PubGeneMTSS1
iHOPMTSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:52:17 CEST 2013
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