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MTSS1 (metastasis suppressor 1)

Identity

Other namesMIM
MIMA
MIMB
HGNC (Hugo) MTSS1
LocusID (NCBI) 9788
Atlas_Id 41450
Location 8q24.13
Location_base_pair Starts at 125563011 and ends at 125740748 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTSS1   20443
Cards
Entrez_Gene (NCBI)MTSS1  9788  metastasis suppressor 1
GeneCards (Weizmann)MTSS1
Ensembl hg19 (Hinxton)ENSG00000170873 [Gene_View]  chr8:125563011-125740748 [Contig_View]  MTSS1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000170873 [Gene_View]  chr8:125563011-125740748 [Contig_View]  MTSS1 [Vega]
ICGC DataPortalENSG00000170873
TCGA cBioPortalMTSS1
AceView (NCBI)MTSS1
Genatlas (Paris)MTSS1
WikiGenes9788
SOURCE (Princeton)MTSS1
Genomic and cartography
GoldenPath hg19 (UCSC)MTSS1  -     chr8:125563011-125740748 -  8q24.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MTSS1  -     8q24.13   [Description]    (hg38-Dec_2013)
EnsemblMTSS1 - 8q24.13 [CytoView hg19]  MTSS1 - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBIMTSS1 [Mapview hg19]  MTSS1 [Mapview hg38]
OMIM608486   
Gene and transcription
Genbank (Entrez)AB007889 AF086645 AF116674 AI041104 AJ710067
RefSeq transcript (Entrez)NM_001282971 NM_001282974 NM_014751
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)MTSS1
Cluster EST : UnigeneHs.700429 [ NCBI ]
CGAP (NCI)Hs.700429
Alternative Splicing : Fast-db (Paris)GSHG0029843
Alternative Splicing GalleryENSG00000170873
Gene ExpressionMTSS1 [ NCBI-GEO ]     MTSS1 [ SEEK ]   MTSS1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43312 (Uniprot)
NextProtO43312  [Medical]
With graphics : InterProO43312
Splice isoforms : SwissVarO43312 (Swissvar)
Domaine pattern : Prosite (Expaxy)IMD (PS51338)    WH2 (PS51082)   
Domains : Interpro (EBI)I-BAR_dom    MIM    MIM/ABBA    WH2_dom   
Related proteins : CluSTrO43312
Domain families : Pfam (Sanger)IMD (PF08397)    WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam08397    pfam02205   
Domain families : Smart (EMBL)WH2 (SM00246)  
DMDM Disease mutations9788
Blocks (Seattle)O43312
PDB (SRS)2D1K   
PDB (PDBSum)2D1K   
PDB (IMB)2D1K   
PDB (RSDB)2D1K   
Human Protein AtlasENSG00000170873
Peptide AtlasO43312
HPRD12243
IPIIPI00983960   IPI00647454   IPI00444645   IPI00922364   IPI00445073   IPI00383355   IPI00152331   IPI00982324   IPI00975593   IPI00976780   IPI00980503   
Protein Interaction databases
DIP (DOE-UCLA)O43312
IntAct (EBI)O43312
FunCoupENSG00000170873
BioGRIDMTSS1
IntegromeDBMTSS1
STRING (EMBL)MTSS1
Ontologies - Pathways
QuickGOO43312
Ontology : AmiGOin utero embryonic development  ruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  adherens junction  movement of cell or subcellular component  plasma membrane organization  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  magnesium ion homeostasis  actin cytoskeleton  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  bone mineralization  positive regulation of actin filament bundle assembly  adherens junction maintenance  identical protein binding  negative regulation of epithelial cell proliferation  actin filament binding  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Ontology : EGO-EBIin utero embryonic development  ruffle  actin monomer binding  receptor binding  protein binding  cytoplasm  adherens junction  movement of cell or subcellular component  plasma membrane organization  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  magnesium ion homeostasis  actin cytoskeleton  microspike assembly  actin cytoskeleton organization  actin filament polymerization  endocytic vesicle  bone mineralization  positive regulation of actin filament bundle assembly  adherens junction maintenance  identical protein binding  negative regulation of epithelial cell proliferation  actin filament binding  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Protein Interaction DatabaseMTSS1
DoCM (Curated mutations)MTSS1
Wikipedia pathwaysMTSS1
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerMTSS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTSS1
dbVarMTSS1
ClinVarMTSS1
1000_GenomesMTSS1 
Exome Variant ServerMTSS1
SNP (GeneSNP Utah)MTSS1
SNP : HGBaseMTSS1
Genetic variants : HAPMAPMTSS1
Genomic Variants (DGV)MTSS1 [DGVbeta]
Mutations
ICGC Data PortalMTSS1 
TCGA Data PortalMTSS1 
Tumor PortalMTSS1
Somatic Mutations in Cancer : COSMICMTSS1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)8:125563011-125740748
CONAN: Copy Number AnalysisMTSS1 
Mutations and Diseases : HGMDMTSS1
OMIM608486   
MedgenMTSS1
NextProtO43312 [Medical]
GENETestsMTSS1
Disease Genetic AssociationMTSS1
Huge Navigator MTSS1 [HugePedia]  MTSS1 [HugeCancerGEM]
snp3D : Map Gene to Disease9788
DGIdb (Drug Gene Interaction db)MTSS1
General knowledge
Homologs : HomoloGeneMTSS1
Homology/Alignments : Family Browser (UCSC)MTSS1
Phylogenetic Trees/Animal Genes : TreeFamMTSS1
Chemical/Protein Interactions : CTD9788
Chemical/Pharm GKB GenePA134892011
Clinical trialMTSS1
Cancer Resource (Charite)ENSG00000170873
Other databases
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
CoreMineMTSS1
GoPubMedMTSS1
iHOPMTSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:43:01 CEST 2015

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