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MTSS1 (MTSS I-BAR domain containing 1)

Identity

Alias (NCBI)MIM
MIMA
MIMB
HGNC (Hugo) MTSS1
HGNC Alias symbKIAA0429
MIMA
MIMB
MIM
HGNC Alias namemissing in metastasis
HGNC Previous namemetastasis suppressor 1
 MTSS1, I-BAR domain containing
LocusID (NCBI) 9788
Atlas_Id 41450
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 124550770 and ends at 124728507 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTSS1 (8q24.13) / ATE1 (10q26.13)MTSS1 (8q24.13) / DDX27 (20q13.13)MTSS1 (8q24.13) / ERBB2 (17q12)
MTSS1 (8q24.13) / FGFR2 (10q26.13)MTSS1 (8q24.13) / KIAA0196 (8q24.13)MTSS1 (8q24.13) / ST3GAL1 (8q24.22)
MTSS1 (8q24.13) / WHSC1L1 (8p11.23)MTSS1 (8q24.13) / ZC2HC1A (8q21.12)TATDN1 (8q24.13) / MTSS1 (8q24.13)
THOC2 (Xq25) / MTSS1 (8q24.13)MTSS1 8q24.13 / DDX27 20q13.13MTSS1 8q24.13 FAM164A
MTSS1 8q24.13 / ST3GAL1 8q24.22MTSS1 8q24.13 / WHSC1L1 8p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MTSS1   20443
Cards
Entrez_Gene (NCBI)MTSS1    MTSS I-BAR domain containing 1
AliasesMIM; MIMA; MIMB
GeneCards (Weizmann)MTSS1
Ensembl hg19 (Hinxton)ENSG00000170873 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170873 [Gene_View]  ENSG00000170873 [Sequence]  chr8:124550770-124728507 [Contig_View]  MTSS1 [Vega]
ICGC DataPortalENSG00000170873
TCGA cBioPortalMTSS1
AceView (NCBI)MTSS1
Genatlas (Paris)MTSS1
SOURCE (Princeton)MTSS1
Genetics Home Reference (NIH)MTSS1
Genomic and cartography
GoldenPath hg38 (UCSC)MTSS1  -     chr8:124550770-124728507 -  8q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MTSS1  -     8q24.13   [Description]    (hg19-Feb_2009)
GoldenPathMTSS1 - 8q24.13 [CytoView hg19]  MTSS1 - 8q24.13 [CytoView hg38]
ImmunoBaseENSG00000170873
Genome Data Viewer NCBIMTSS1 [Mapview hg19]  
OMIM608486   
Gene and transcription
Genbank (Entrez)AB007889 AF086645 AF116674 AI041104 AJ710067
RefSeq transcript (Entrez)NM_001282971 NM_001282974 NM_001363294 NM_001363295 NM_001363296 NM_001363297 NM_001363298 NM_001363299 NM_001363300 NM_001363301 NM_001363302 NM_014751
Consensus coding sequences : CCDS (NCBI)MTSS1
Gene ExpressionMTSS1 [ NCBI-GEO ]   MTSS1 [ EBI - ARRAY_EXPRESS ]   MTSS1 [ SEEK ]   MTSS1 [ MEM ]
Gene Expression Viewer (FireBrowse)MTSS1 [ Firebrowse - Broad ]
GenevisibleExpression of MTSS1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9788
GTEX Portal (Tissue expression)MTSS1
Human Protein AtlasENSG00000170873-MTSS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43312   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43312  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43312
PhosPhoSitePlusO43312
Domaine pattern : Prosite (Expaxy)IMD (PS51338)    WH2 (PS51082)   
Domains : Interpro (EBI)AH/BAR_dom_sf    I-BAR_dom    MTSS1    MTSS1/MTSS2    WH2_dom   
Domain families : Pfam (Sanger)IMD (PF08397)    WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam08397    pfam02205   
Conserved Domain (NCBI)MTSS1
PDB (RSDB)2D1K   
PDB Europe2D1K   
PDB (PDBSum)2D1K   
PDB (IMB)2D1K   
Structural Biology KnowledgeBase2D1K   
SCOP (Structural Classification of Proteins)2D1K   
CATH (Classification of proteins structures)2D1K   
SuperfamilyO43312
AlphaFold pdb e-kbO43312   
Human Protein Atlas [tissue]ENSG00000170873-MTSS1 [tissue]
HPRD12243
Protein Interaction databases
DIP (DOE-UCLA)O43312
IntAct (EBI)O43312
BioGRIDMTSS1
STRING (EMBL)MTSS1
ZODIACMTSS1
Ontologies - Pathways
QuickGOO43312
Ontology : AmiGOruffle  actin monomer binding  signaling receptor binding  protein binding  cytoplasm  plasma membrane organization  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  actin cytoskeleton  microspike assembly  actin cytoskeleton organization  endocytic vesicle  identical protein binding  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
Ontology : EGO-EBIruffle  actin monomer binding  signaling receptor binding  protein binding  cytoplasm  plasma membrane organization  cell adhesion  transmembrane receptor protein tyrosine kinase signaling pathway  actin cytoskeleton  microspike assembly  actin cytoskeleton organization  endocytic vesicle  identical protein binding  negative regulation of epithelial cell proliferation  renal tubule morphogenesis  cellular response to fluid shear stress  glomerulus morphogenesis  nephron tubule epithelial cell differentiation  epithelial cell proliferation involved in renal tubule morphogenesis  
NDEx NetworkMTSS1
Atlas of Cancer Signalling NetworkMTSS1
Wikipedia pathwaysMTSS1
Orthology - Evolution
OrthoDB9788
GeneTree (enSembl)ENSG00000170873
Phylogenetic Trees/Animal Genes : TreeFamMTSS1
Homologs : HomoloGeneMTSS1
Homology/Alignments : Family Browser (UCSC)MTSS1
Gene fusions - Rearrangements
Fusion : MitelmanMTSS1/DDX27 [8q24.13/20q13.13]  
Fusion : MitelmanMTSS1/ST3GAL1 [8q24.13/8q24.22]  
Fusion : MitelmanMTSS1/WHSC1L1 [8q24.13/8p11.23]  
Fusion : MitelmanMTSS1/ZC2HC1A [8q24.13/8q21.12]  
Fusion : QuiverMTSS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMTSS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTSS1
dbVarMTSS1
ClinVarMTSS1
MonarchMTSS1
1000_GenomesMTSS1 
Exome Variant ServerMTSS1
GNOMAD BrowserENSG00000170873
Varsome BrowserMTSS1
ACMGMTSS1 variants
VarityO43312
Genomic Variants (DGV)MTSS1 [DGVbeta]
DECIPHERMTSS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMTSS1 
Mutations
ICGC Data PortalMTSS1 
TCGA Data PortalMTSS1 
Broad Tumor PortalMTSS1
OASIS PortalMTSS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMTSS1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMTSS1
Mutations and Diseases : HGMDMTSS1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMTSS1
DgiDB (Drug Gene Interaction Database)MTSS1
DoCM (Curated mutations)MTSS1
CIViC (Clinical Interpretations of Variants in Cancer)MTSS1
Cancer3DMTSS1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608486   
Orphanet
DisGeNETMTSS1
MedgenMTSS1
Genetic Testing Registry MTSS1
NextProtO43312 [Medical]
GENETestsMTSS1
Target ValidationMTSS1
Huge Navigator MTSS1 [HugePedia]
ClinGenMTSS1
Clinical trials, drugs, therapy
MyCancerGenomeMTSS1
Protein Interactions : CTDMTSS1
Pharm GKB GenePA134892011
PharosO43312
Clinical trialMTSS1
Miscellaneous
canSAR (ICR)MTSS1
HarmonizomeMTSS1
DataMed IndexMTSS1
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMTSS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:21:35 CEST 2021

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