MTSS1 (MTSS I-BAR domain containing 1)

2003-10-01  

Identity

HGNC
LOCATION
8q24.13
LOCUSID
ALIAS
MIM,MIMA,MIMB
FUSION GENES

Other Information

Locus ID:

NCBI: 9788
MIM: 608486
HGNC: 20443
Ensembl: ENSG00000170873

Variants:

dbSNP: 9788
ClinVar: 9788
TCGA: ENSG00000170873
COSMIC: MTSS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170873ENST00000325064O43312
ENSG00000170873ENST00000378017O43312
ENSG00000170873ENST00000431961O43312
ENSG00000170873ENST00000518547O43312
ENSG00000170873ENST00000519168H0YB53
ENSG00000170873ENST00000522118E5RJX3
ENSG00000170873ENST00000522162H0YBL3
ENSG00000170873ENST00000523179H0YAZ8
ENSG00000170873ENST00000524090E7EWW5

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
147521062004A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.74
226817172012MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma.71
120825442002MIM, a potential metastasis suppressor gene in bladder cancer.64
155456302004MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription.63
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
233832072013MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer.57
234747512014Suppression of MIM by microRNA-182 activates RhoA and promotes breast cancer metastasis.48
193286782009Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer.47
200806502010Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.46
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45

Citation

Dessen P

MTSS1 (MTSS I-BAR domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/41450/mtss1