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MTTP (microsomal triglyceride transfer protein)

Identity

Other namesABL
MTP
HGNC (Hugo) MTTP
LocusID (NCBI) 4547
Location 4q23
Location_base_pair Starts at 100485240 and ends at 100545154 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MTTP   7467
Cards
Entrez_Gene (NCBI)MTTP  4547  microsomal triglyceride transfer protein
GeneCards (Weizmann)MTTP
Ensembl hg19 (Hinxton)ENSG00000138823 [Gene_View]  chr4:100485240-100545154 [Contig_View]  MTTP [Vega]
Ensembl hg38 (Hinxton)ENSG00000138823 [Gene_View]  chr4:100485240-100545154 [Contig_View]  MTTP [Vega]
ICGC DataPortalENSG00000138823
cBioPortalMTTP
AceView (NCBI)MTTP
Genatlas (Paris)MTTP
WikiGenes4547
SOURCE (Princeton)MTTP
Genomic and cartography
GoldenPath hg19 (UCSC)MTTP  -     chr4:100485240-100545154 +  4q23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MTTP  -     4q23   [Description]    (hg38-Dec_2013)
EnsemblMTTP - 4q23 [CytoView hg19]  MTTP - 4q23 [CytoView hg38]
Mapping of homologs : NCBIMTTP [Mapview hg19]  MTTP [Mapview hg38]
OMIM157147   200100   605552   
Gene and transcription
Genbank (Entrez)AA609331 AI623321 AK225328 AK290793 AK302602
RefSeq transcript (Entrez)NM_000253 NM_001300785
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NG_011469 NT_016354 NW_001838915 NW_004929320
Consensus coding sequences : CCDS (NCBI)MTTP
Cluster EST : UnigeneHs.195799 [ NCBI ]
CGAP (NCI)Hs.195799
Alternative Splicing : Fast-db (Paris)GSHG0022753
Alternative Splicing GalleryENSG00000138823
Gene ExpressionMTTP [ NCBI-GEO ]     MTTP [ SEEK ]   MTTP [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55157 (Uniprot)
NextProtP55157  [Medical]
With graphics : InterProP55157
Splice isoforms : SwissVarP55157 (Swissvar)
Domaine pattern : Prosite (Expaxy)VITELLOGENIN (PS51211)   
Domains : Interpro (EBI)Lipid_transp_b-sht_shell    Lipid_transpt_N    Vitellinogen_b-sht_N    Vitellinogen_superhlx   
Related proteins : CluSTrP55157
Domain families : Pfam (Sanger)Vitellogenin_N (PF01347)   
Domain families : Pfam (NCBI)pfam01347   
Domain families : Smart (EMBL)LPD_N (SM00638)  
DMDM Disease mutations4547
Blocks (Seattle)P55157
Human Protein AtlasENSG00000138823
Peptide AtlasP55157
HPRD01144
IPIIPI00296645   IPI01011609   IPI00967313   IPI00441046   IPI00968150   IPI00967906   IPI00964771   IPI00963863   IPI00965537   IPI00967575   IPI00964117   
Protein Interaction databases
DIP (DOE-UCLA)P55157
IntAct (EBI)P55157
FunCoupENSG00000138823
BioGRIDMTTP
IntegromeDBMTTP
STRING (EMBL)MTTP
Ontologies - Pathways
QuickGOP55157
Ontology : AmiGOlipid transporter activity  endoplasmic reticulum lumen  rough endoplasmic reticulum  Golgi apparatus  protein lipidation  lipid metabolic process  triglyceride metabolic process  lipid transport  lipid binding  basolateral plasma membrane  brush border membrane  microvillus membrane  membrane-bounded vesicle  apolipoprotein binding  lipoprotein metabolic process  cholesterol homeostasis  lipoprotein transport  receptor complex  small molecule metabolic process  protein heterodimerization activity  response to calcium ion  
Ontology : EGO-EBIlipid transporter activity  endoplasmic reticulum lumen  rough endoplasmic reticulum  Golgi apparatus  protein lipidation  lipid metabolic process  triglyceride metabolic process  lipid transport  lipid binding  basolateral plasma membrane  brush border membrane  microvillus membrane  membrane-bounded vesicle  apolipoprotein binding  lipoprotein metabolic process  cholesterol homeostasis  lipoprotein transport  receptor complex  small molecule metabolic process  protein heterodimerization activity  response to calcium ion  
Pathways : KEGGFat digestion and absorption   
Protein Interaction DatabaseMTTP
DoCM (Curated mutations)MTTP
Wikipedia pathwaysMTTP
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerMTTP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MTTP
dbVarMTTP
ClinVarMTTP
1000_GenomesMTTP 
Exome Variant ServerMTTP
SNP (GeneSNP Utah)MTTP
SNP : HGBaseMTTP
Genetic variants : HAPMAPMTTP
Genomic VariantsMTTP  MTTP [DGVbeta]
Mutations
ICGC Data PortalENSG00000138823 
Somatic Mutations in Cancer : COSMICMTTP 
CONAN: Copy Number AnalysisMTTP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)MitoLSDB
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:100485240-100545154
Mutations and Diseases : HGMDMTTP
OMIM157147    200100    605552   
MedgenMTTP
NextProtP55157 [Medical]
GENETestsMTTP
Disease Genetic AssociationMTTP
Huge Navigator MTTP [HugePedia]  MTTP [HugeCancerGEM]
snp3D : Map Gene to Disease4547
DGIdb (Drug Gene Interaction db)MTTP
General knowledge
Homologs : HomoloGeneMTTP
Homology/Alignments : Family Browser (UCSC)MTTP
Phylogenetic Trees/Animal Genes : TreeFamMTTP
Chemical/Protein Interactions : CTD4547
Chemical/Pharm GKB GenePA164742099
Clinical trialMTTP
Cancer Resource (Charite)ENSG00000138823
Other databases
Probes
Litterature
PubMed119 Pubmed reference(s) in Entrez
CoreMineMTTP
GoPubMedMTTP
iHOPMTTP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:21:04 CET 2014

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