MTX2 (metaxin 2)

2014-11-01  

Identity

HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
MDPS,metaxin-2
FUSION GENES

Other Information

Locus ID:

NCBI: 10651
MIM: 608555
HGNC: 7506
Ensembl: ENSG00000128654

Variants:

dbSNP: 10651
ClinVar: 10651
TCGA: ENSG00000128654
COSMIC: MTX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128654ENST00000249442O75431
ENSG00000128654ENST00000420864F8WCW1
ENSG00000128654ENST00000423461F8WE26
ENSG00000128654ENST00000443241C9JNK6
ENSG00000128654ENST00000452865C9JAZ1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
176243302007The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
175106552007Conserved roles of Sam50 and metaxins in VDAC biogenesis.31
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17

Citation

Dessen P

MTX2 (metaxin 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70579/mtx2