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MUC1 (mucin 1, cell surface associated)

Identity

Alias (NCBI)ADMCKD
ADMCKD1
ADTKD2
CA 15-3
CD227
EMA
H23AG
KL-6
MAM6
MCD
MCKD
MCKD1
MUC-1
MUC-1/SEC
MUC-1/X
MUC1/ZD
PEM
PEMT
PUM
HGNC (Hugo) MUC1
HGNC Alias symbCD227
PEM
ADMCKD
ADMCKD1
MCKD
MCD
HGNC Previous namePUM
 MCKD1
HGNC Previous namemucin 1, transmembrane
 medullary cystic kidney disease 1 (autosomal dominant)
LocusID (NCBI) 4582
Atlas_Id 41453
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155185824 and ends at 155192909 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HCN3 (1q22) / MUC1 (1q22)IGH (14q32.33) / MUC1 (1q22)IGHG1 (14q32.33) / MUC1 (1q22)
Ig () / MUC1 (1q22)LGALS4 (19q13.2) / MUC1 (1q22)MUC1 (1q22) / IGH (14q32.33)
MUC1 (1q22) / LGALS4 (19q13.2)MUC1 (1q22) / MUC1 (1q22)MUC1 (1q22) / PKLR (1q22)
MUC1 (1q22) / SIAE (11q24.2)YBX1 (1p34.2) / MUC1 (1q22)MUC1 1q22 / PKLR 1q22
MUC1 1q22 / SIAE 11q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 5 ]
  t(1;1)(p36;q21) in Non Hodgkin Lymphoma
t(1;14)(q21;q32) BCL9/IGH::t(1;22)(q21;q11) IGL/BCL9
t(1;14)(q21;q32) FCRL4/IGH
t(1;14)(q21;q32)::t(1;22)(q21;q11)
t(1;14)(q21;q32) MUC1/IGH


External links

Nomenclature
HGNC (Hugo)MUC1   7508
Cards
Entrez_Gene (NCBI)MUC1    mucin 1, cell surface associated
AliasesADMCKD; ADMCKD1; ADTKD2; CA; 
CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
GeneCards (Weizmann)MUC1
Ensembl hg19 (Hinxton)ENSG00000185499 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185499 [Gene_View]  ENSG00000185499 [Sequence]  chr1:155185824-155192909 [Contig_View]  MUC1 [Vega]
ICGC DataPortalENSG00000185499
TCGA cBioPortalMUC1
AceView (NCBI)MUC1
Genatlas (Paris)MUC1
SOURCE (Princeton)MUC1
Genetics Home Reference (NIH)MUC1
Genomic and cartography
GoldenPath hg38 (UCSC)MUC1  -     chr1:155185824-155192909 -  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MUC1  -     1q22   [Description]    (hg19-Feb_2009)
GoldenPathMUC1 - 1q22 [CytoView hg19]  MUC1 - 1q22 [CytoView hg38]
ImmunoBaseENSG00000185499
genome Data Viewer NCBIMUC1 [Mapview hg19]  
OMIM158340   174000   
Gene and transcription
Genbank (Entrez)AA425062 AF125525 AF348143 AH001451 AH001451
RefSeq transcript (Entrez)NM_001018016 NM_001018017 NM_001018021 NM_001044390 NM_001044391 NM_001044392 NM_001044393 NM_001204285 NM_001204286 NM_001204287 NM_001204288 NM_001204289 NM_001204290 NM_001204291 NM_001204292 NM_001204293 NM_001204294 NM_001204295 NM_001204296 NM_001204297 NM_001371720 NM_002456 NM_182741
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MUC1
Alternative Splicing GalleryENSG00000185499
Gene ExpressionMUC1 [ NCBI-GEO ]   MUC1 [ EBI - ARRAY_EXPRESS ]   MUC1 [ SEEK ]   MUC1 [ MEM ]
Gene Expression Viewer (FireBrowse)MUC1 [ Firebrowse - Broad ]
GenevisibleExpression of MUC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4582
GTEX Portal (Tissue expression)MUC1
Human Protein AtlasENSG00000185499-MUC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)MUC1
Blocks (Seattle)MUC1
Human Protein Atlas [tissue]ENSG00000185499-MUC1 [tissue]
HPRD01152
IPIIPI00013955   IPI00902840   IPI00218163   IPI00218164   IPI00218165   IPI00218166   IPI00218168   IPI00218169   IPI00607673   IPI00385165   IPI01016012   IPI00855927   IPI01025299   IPI00385161   IPI01020759   IPI00876878   IPI00844244   IPI00975472   IPI00916285   IPI00982300   IPI00852677   IPI00984154   IPI00984788   IPI00982802   IPI00385178   IPI00978078   IPI00889553   IPI00607569   IPI00385172   IPI00641632   IPI00646925   
Protein Interaction databases
BioGRIDMUC1
STRING (EMBL)MUC1
ZODIACMUC1
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMUC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 25 19:35:13 CET 2021

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