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MUC21 (mucin 21, cell surface associated)

Identity

Alias_namesC6orf205
chromosome 6 open reading frame 205
Alias_symbol (synonym)bCX31G15.2
Other aliasKMQK697
MUC-21
HGNC (Hugo) MUC21
LocusID (NCBI) 394263
Atlas_Id 54480
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 30983708 and ends at 30989902 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HLA-DOA (6p21.32) / MUC21 (6p21.33)KRT13 (17q21.2) / MUC21 (6p21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Squamous Cell Carcinoma
HLA-DOA/MUC21 (6p21)


External links

Nomenclature
HGNC (Hugo)MUC21   21661
Cards
Entrez_Gene (NCBI)MUC21  394263  mucin 21, cell surface associated
AliasesC6orf205; KMQK697; MUC-21
GeneCards (Weizmann)MUC21
Ensembl hg19 (Hinxton)ENSG00000204544 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204544 [Gene_View]  ENSG00000204544 [Sequence]  chr6:30983708-30989902 [Contig_View]  MUC21 [Vega]
ICGC DataPortalENSG00000204544
TCGA cBioPortalMUC21
AceView (NCBI)MUC21
Genatlas (Paris)MUC21
WikiGenes394263
SOURCE (Princeton)MUC21
Genetics Home Reference (NIH)MUC21
Genomic and cartography
GoldenPath hg38 (UCSC)MUC21  -     chr6:30983708-30989902 +  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MUC21  -     6p21.33   [Description]    (hg19-Feb_2009)
EnsemblMUC21 - 6p21.33 [CytoView hg19]  MUC21 - 6p21.33 [CytoView hg38]
Mapping of homologs : NCBIMUC21 [Mapview hg19]  MUC21 [Mapview hg38]
OMIM616991   
Gene and transcription
Genbank (Entrez)AB242595 AK056612 AK298642 AK299471 AK301645
RefSeq transcript (Entrez)NM_001010909 NM_001322370 NM_001322371
RefSeq genomic (Entrez)NC_000006 NG_054937 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248
Consensus coding sequences : CCDS (NCBI)MUC21
Cluster EST : UnigeneHs.448277 [ NCBI ]
CGAP (NCI)Hs.448277
Alternative Splicing GalleryENSG00000204544
Gene ExpressionMUC21 [ NCBI-GEO ]   MUC21 [ EBI - ARRAY_EXPRESS ]   MUC21 [ SEEK ]   MUC21 [ MEM ]
Gene Expression Viewer (FireBrowse)MUC21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)394263
GTEX Portal (Tissue expression)MUC21
Human Protein AtlasENSG00000204544-MUC21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5SSG8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5SSG8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5SSG8
Splice isoforms : SwissVarQ5SSG8
PhosPhoSitePlusQ5SSG8
Domains : Interpro (EBI)MUC21    Mucin_dom    Tandem-repeating_mucin   
Domain families : Pfam (Sanger)Epiglycanin_C (PF14654)    Epiglycanin_TR (PF05647)   
Domain families : Pfam (NCBI)pfam14654    pfam05647   
Conserved Domain (NCBI)MUC21
DMDM Disease mutations394263
Blocks (Seattle)MUC21
SuperfamilyQ5SSG8
Human Protein Atlas [tissue]ENSG00000204544-MUC21 [tissue]
Peptide AtlasQ5SSG8
HPRD16665
IPIIPI00647489   IPI00895899   IPI00895926   IPI00514786   IPI00876924   
Protein Interaction databases
DIP (DOE-UCLA)Q5SSG8
IntAct (EBI)Q5SSG8
FunCoupENSG00000204544
BioGRIDMUC21
STRING (EMBL)MUC21
ZODIACMUC21
Ontologies - Pathways
QuickGOQ5SSG8
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  Golgi lumen  plasma membrane  plasma membrane  integral component of membrane  O-glycan processing  negative regulation of cell-cell adhesion  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  Golgi lumen  plasma membrane  plasma membrane  integral component of membrane  O-glycan processing  negative regulation of cell-cell adhesion  
NDEx NetworkMUC21
Atlas of Cancer Signalling NetworkMUC21
Wikipedia pathwaysMUC21
Orthology - Evolution
OrthoDB394263
GeneTree (enSembl)ENSG00000204544
Phylogenetic Trees/Animal Genes : TreeFamMUC21
HOVERGENQ5SSG8
HOGENOMQ5SSG8
Homologs : HomoloGeneMUC21
Homology/Alignments : Family Browser (UCSC)MUC21
Gene fusions - Rearrangements
Fusion : MitelmanHLA-DOA/MUC21 [6p21.32/6p21.33]  [t(6;6)(p21;p21)]  
Fusion : QuiverMUC21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMUC21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MUC21
dbVarMUC21
ClinVarMUC21
1000_GenomesMUC21 
Exome Variant ServerMUC21
ExAC (Exome Aggregation Consortium)ENSG00000204544
GNOMAD BrowserENSG00000204544
Varsome BrowserMUC21
Genetic variants : HAPMAP394263
Genomic Variants (DGV)MUC21 [DGVbeta]
DECIPHERMUC21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMUC21 
Mutations
ICGC Data PortalMUC21 
TCGA Data PortalMUC21 
Broad Tumor PortalMUC21
OASIS PortalMUC21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMUC21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMUC21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MUC21
DgiDB (Drug Gene Interaction Database)MUC21
DoCM (Curated mutations)MUC21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MUC21 (select a term)
intoGenMUC21
Cancer3DMUC21(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616991   
Orphanet
DisGeNETMUC21
MedgenMUC21
Genetic Testing Registry MUC21
NextProtQ5SSG8 [Medical]
TSGene394263
GENETestsMUC21
Target ValidationMUC21
Huge Navigator MUC21 [HugePedia]
snp3D : Map Gene to Disease394263
BioCentury BCIQMUC21
ClinGenMUC21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD394263
Chemical/Pharm GKB GenePA162396305
Clinical trialMUC21
Miscellaneous
canSAR (ICR)MUC21 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMUC21
EVEXMUC21
GoPubMedMUC21
iHOPMUC21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:24:18 CET 2018

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