| Nomenclature |
|---|
| HGNC (Hugo) | MXD1 6761 |
| Cards |
|---|
| Entrez_Gene (NCBI) | MXD1 MAX dimerization protein 1 |
| Aliases | BHLHC58; MAD; MAD1 |
| GeneCards (Weizmann) | MXD1 |
| Ensembl hg19 (Hinxton) | ENSG00000059728 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000059728 [Gene_View] ENSG00000059728 [Sequence] chr2:69915109-69942944 [Contig_View] MXD1 [Vega] |
| ICGC DataPortal | ENSG00000059728 |
| TCGA cBioPortal | MXD1 |
| AceView (NCBI) | MXD1 |
| Genatlas (Paris) | MXD1 |
| SOURCE (Princeton) | MXD1 |
| Genetics Home Reference (NIH) | MXD1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | MXD1 - chr2:69915109-69942944 + 2p13.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | MXD1 - 2p13.3 [Description] (hg19-Feb_2009) |
| GoldenPath | MXD1 - 2p13.3 [CytoView hg19] MXD1 - 2p13.3 [CytoView hg38] |
| ImmunoBase | ENSG00000059728 |
| genome Data Viewer NCBI | MXD1 [Mapview hg19] |
| OMIM | 600021 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK301088 AK312734 BC036402 BC051693 BC069377 |
| RefSeq transcript (Entrez) | NM_001202513 NM_001202514 NM_002357 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | MXD1 |
| Alternative Splicing Gallery | ENSG00000059728 |
| Gene Expression | MXD1 [ NCBI-GEO ] MXD1 [ EBI - ARRAY_EXPRESS ]
MXD1 [ SEEK ] MXD1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | MXD1 [ Firebrowse - Broad ] |
| Genevisible | Expression of MXD1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 4084 |
| GTEX Portal (Tissue expression) | MXD1 |
| Human Protein Atlas | ENSG00000059728-MXD1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q05195 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q05195 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q05195 |
| Splice isoforms : SwissVar | Q05195 |
| PhosPhoSitePlus | Q05195 |
| Domaine pattern : Prosite (Expaxy) | BHLH (PS50888) |
| Domains : Interpro (EBI) | bHLH_dom HLH_DNA-bd_sf MXD1 |
| Domain families : Pfam (Sanger) | HLH (PF00010) |
| Domain families : Pfam (NCBI) | pfam00010 |
| Domain families : Smart (EMBL) | HLH (SM00353) |
| Conserved Domain (NCBI) | MXD1 |
| Blocks (Seattle) | MXD1 |
| PDB (RSDB) | 1E91 1G1E 1NLW 1PD7 1S5Q |
| PDB Europe | 1E91 1G1E 1NLW 1PD7 1S5Q |
| PDB (PDBSum) | 1E91 1G1E 1NLW 1PD7 1S5Q |
| PDB (IMB) | 1E91 1G1E 1NLW 1PD7 1S5Q |
| Structural Biology KnowledgeBase | 1E91 1G1E 1NLW 1PD7 1S5Q |
| SCOP (Structural Classification of Proteins) | 1E91 1G1E 1NLW 1PD7 1S5Q |
| CATH (Classification of proteins structures) | 1E91 1G1E 1NLW 1PD7 1S5Q |
| Superfamily | Q05195 |
| Human Protein Atlas [tissue] | ENSG00000059728-MXD1 [tissue] |
| Peptide Atlas | Q05195 |
| HPRD | 02487 |
| IPI | IPI00012034 IPI00916101 IPI00980106 IPI00976926 IPI00915965 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q05195 |
| IntAct (EBI) | Q05195 |
| BioGRID | MXD1 |
| STRING (EMBL) | MXD1 |
| ZODIAC | MXD1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q05195 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription corepressor activity protein binding nucleus nucleoplasm mitochondrion cytosol protein dimerization activity |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin nuclear chromatin RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription corepressor activity protein binding nucleus nucleoplasm mitochondrion cytosol protein dimerization activity |
| NDEx Network | MXD1 |
| Atlas of Cancer Signalling Network | MXD1 |
| Wikipedia pathways | MXD1 |
| Orthology - Evolution |
|---|
| OrthoDB | 4084 |
| GeneTree (enSembl) | ENSG00000059728 |
| Phylogenetic Trees/Animal Genes : TreeFam | MXD1 |
| HOGENOM | Q05195 |
| Homologs : HomoloGene | MXD1 |
| Homology/Alignments : Family Browser (UCSC) | MXD1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | MXD1/ANTXR1 [2p13.3/2p13.3] |
| Fusion Portal | MXD1 2p13.3 ANTXR1 2p13.3 OV |
| Fusion : Quiver | MXD1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | MXD1 [hg38] |
| dbVar | MXD1 |
| ClinVar | MXD1 |
| Monarch | MXD1 |
| 1000_Genomes | MXD1 |
| Exome Variant Server | MXD1 |
| GNOMAD Browser | ENSG00000059728 |
| Varsome Browser | MXD1 |
| Genomic Variants (DGV) | MXD1 [DGVbeta] |
| DECIPHER | MXD1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | MXD1 |
| Mutations |
|---|
| ICGC Data Portal | MXD1 |
| TCGA Data Portal | MXD1 |
| Broad Tumor Portal | MXD1 |
| OASIS Portal | MXD1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | MXD1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | MXD1 |
| Mutations and Diseases : HGMD | MXD1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search MXD1 |
| DgiDB (Drug Gene Interaction Database) | MXD1 |
| DoCM (Curated mutations) | MXD1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | MXD1 (select a term) |
| intoGen | MXD1 |
| Cancer3D | MXD1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600021 |
| Orphanet | |
| DisGeNET | MXD1 |
| Medgen | MXD1 |
| Genetic Testing Registry | MXD1
|
| NextProt | Q05195 [Medical] |
| GENETests | MXD1 |
| Target Validation | MXD1 |
| Huge Navigator |
MXD1 [HugePedia] |
| ClinGen | MXD1 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | MXD1 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA30520 |
| Pharos | Q05195 |
| Clinical trial | MXD1 |
| Miscellaneous |
|---|
| canSAR (ICR) | MXD1 (select the gene name) |
| Harmonizome | MXD1 |
| DataMed Index | MXD1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 67 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | MXD1 |
