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MXD3 (MAX dimerization protein 3)

Identity

Alias (NCBI)BHLHC13
MAD3
MYX
HGNC (Hugo) MXD3
HGNC Alias symbMAD3
bHLHc13
LocusID (NCBI) 83463
Atlas_Id 56413
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 177307210 and ends at 177311898 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKH (5p15.2) / MXD3 (5q35.3)LMAN2 (5q35.3) / MXD3 (5q35.3)MXD3 (5q35.3) / EME2 (16p13.3)
MXD3 (5q35.3) / PYCR2 (1q42.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MXD3   14008
Cards
Entrez_Gene (NCBI)MXD3    MAX dimerization protein 3
AliasesBHLHC13; MAD3; MYX
GeneCards (Weizmann)MXD3
Ensembl hg19 (Hinxton)ENSG00000213347 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213347 [Gene_View]  ENSG00000213347 [Sequence]  chr5:177307210-177311898 [Contig_View]  MXD3 [Vega]
ICGC DataPortalENSG00000213347
TCGA cBioPortalMXD3
AceView (NCBI)MXD3
Genatlas (Paris)MXD3
SOURCE (Princeton)MXD3
Genetics Home Reference (NIH)MXD3
Genomic and cartography
GoldenPath hg38 (UCSC)MXD3  -     chr5:177307210-177311898 -  5q35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MXD3  -     5q35.3   [Description]    (hg19-Feb_2009)
GoldenPathMXD3 - 5q35.3 [CytoView hg19]  MXD3 - 5q35.3 [CytoView hg38]
ImmunoBaseENSG00000213347
Genome Data Viewer NCBIMXD3 [Mapview hg19]  
OMIM609450   
Gene and transcription
Genbank (Entrez)AF114834 AK057034 AK092842 AK222579 AK303397
RefSeq transcript (Entrez)NM_001142935 NM_001394986 NM_001394987 NM_031300
Consensus coding sequences : CCDS (NCBI)MXD3
Gene ExpressionMXD3 [ NCBI-GEO ]   MXD3 [ EBI - ARRAY_EXPRESS ]   MXD3 [ SEEK ]   MXD3 [ MEM ]
Gene Expression Viewer (FireBrowse)MXD3 [ Firebrowse - Broad ]
GenevisibleExpression of MXD3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83463
GTEX Portal (Tissue expression)MXD3
Human Protein AtlasENSG00000213347-MXD3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BW11   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BW11  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BW11
PhosPhoSitePlusQ9BW11
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom    HLH_DNA-bd_sf   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MXD3
SuperfamilyQ9BW11
AlphaFold pdb e-kbQ9BW11   
Human Protein Atlas [tissue]ENSG00000213347-MXD3 [tissue]
HPRD14791
Protein Interaction databases
DIP (DOE-UCLA)Q9BW11
IntAct (EBI)Q9BW11
BioGRIDMXD3
STRING (EMBL)MXD3
ZODIACMXD3
Ontologies - Pathways
QuickGOQ9BW11
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  protein binding  nucleus  regulation of transcription by RNA polymerase II  protein dimerization activity  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  protein binding  nucleus  regulation of transcription by RNA polymerase II  protein dimerization activity  
NDEx NetworkMXD3
Atlas of Cancer Signalling NetworkMXD3
Wikipedia pathwaysMXD3
Orthology - Evolution
OrthoDB83463
GeneTree (enSembl)ENSG00000213347
Phylogenetic Trees/Animal Genes : TreeFamMXD3
Homologs : HomoloGeneMXD3
Homology/Alignments : Family Browser (UCSC)MXD3
Gene fusions - Rearrangements
Fusion : QuiverMXD3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMXD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MXD3
dbVarMXD3
ClinVarMXD3
MonarchMXD3
1000_GenomesMXD3 
Exome Variant ServerMXD3
GNOMAD BrowserENSG00000213347
Varsome BrowserMXD3
ACMGMXD3 variants
VarityQ9BW11
Genomic Variants (DGV)MXD3 [DGVbeta]
DECIPHERMXD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMXD3 
Mutations
ICGC Data PortalMXD3 
TCGA Data PortalMXD3 
Broad Tumor PortalMXD3
OASIS PortalMXD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMXD3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMXD3
Mutations and Diseases : HGMDMXD3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMXD3
DgiDB (Drug Gene Interaction Database)MXD3
DoCM (Curated mutations)MXD3
CIViC (Clinical Interpretations of Variants in Cancer)MXD3
Cancer3DMXD3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609450   
Orphanet
DisGeNETMXD3
MedgenMXD3
Genetic Testing Registry MXD3
NextProtQ9BW11 [Medical]
GENETestsMXD3
Target ValidationMXD3
Huge Navigator MXD3 [HugePedia]
ClinGenMXD3
Clinical trials, drugs, therapy
MyCancerGenomeMXD3
Protein Interactions : CTDMXD3
Pharm GKB GenePA134892226
PharosQ9BW11
Clinical trialMXD3
Miscellaneous
canSAR (ICR)MXD3
HarmonizomeMXD3
DataMed IndexMXD3
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMXD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:21:40 CEST 2021

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