Identity
HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
MAD4,MST149,MSTP149,bHLHc12
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10608
HGNC: 13906
Ensembl: ENSG00000123933
Variants:
dbSNP: 10608
ClinVar: 10608
TCGA: ENSG00000123933
COSMIC: MXD4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000123933 | ENST00000337190 | Q14582 |
| ENSG00000123933 | ENST00000510822 | D6RGV1 |
| ENSG00000123933 | ENST00000513380 | H0Y8Z5 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36007550 | 2023 | MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate. | 1 |
| 36007550 | 2023 | MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate. | 1 |
| 36302855 | 2022 | Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia. | 8 |
| 36302855 | 2022 | Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia. | 8 |
| 33714983 | 2021 | NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis. | 7 |
| 33714983 | 2021 | NUTM1-rearranged colorectal sarcoma: a clinicopathologically and genetically distinctive malignant neoplasm with a poor prognosis. | 7 |
| 22895069 | 2012 | Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells. | 6 |
| 22895069 | 2012 | Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells. | 6 |
| 16167342 | 2005 | c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. | 6 |
| 16167342 | 2005 | c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. | 6 |
| 15469726 | 2004 | Human liver specific transcriptional factor TCP10L binds to MAD4. | 2 |
| 15469726 | 2004 | Human liver specific transcriptional factor TCP10L binds to MAD4. | 2 |
| 12418961 | 2003 | Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc. | 23 |
| 12418961 | 2003 | Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc. | 23 |
Citation
Dessen P
MXD4 (MAX dimerization protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/41465/mxd4
