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MXD4 (MAX dimerization protein 4)

Identity

Alias_symbol (synonym)MAD4
MSTP149
MST149
bHLHc12
Other alias
HGNC (Hugo) MXD4
LocusID (NCBI) 10608
Atlas_Id 41465
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 2247433 and ends at 2262012 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MXD4 (4p16.3) / MXD4 (4p16.3)MXD4 (4p16.3) / PSMC4 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MXD4   13906
Cards
Entrez_Gene (NCBI)MXD4  10608  MAX dimerization protein 4
AliasesMAD4; MST149; MSTP149; bHLHc12
GeneCards (Weizmann)MXD4
Ensembl hg19 (Hinxton)ENSG00000123933 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123933 [Gene_View]  chr4:2247433-2262012 [Contig_View]  MXD4 [Vega]
ICGC DataPortalENSG00000123933
TCGA cBioPortalMXD4
AceView (NCBI)MXD4
Genatlas (Paris)MXD4
WikiGenes10608
SOURCE (Princeton)MXD4
Genetics Home Reference (NIH)MXD4
Genomic and cartography
GoldenPath hg38 (UCSC)MXD4  -     chr4:2247433-2262012 -  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MXD4  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblMXD4 - 4p16.3 [CytoView hg19]  MXD4 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIMXD4 [Mapview hg19]  MXD4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF040963 AF082740 AF187724 AK024501 AK026392
RefSeq transcript (Entrez)NM_006454
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MXD4
Cluster EST : UnigeneHs.655020 [ NCBI ]
CGAP (NCI)Hs.655020
Alternative Splicing GalleryENSG00000123933
Gene ExpressionMXD4 [ NCBI-GEO ]   MXD4 [ EBI - ARRAY_EXPRESS ]   MXD4 [ SEEK ]   MXD4 [ MEM ]
Gene Expression Viewer (FireBrowse)MXD4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10608
GTEX Portal (Tissue expression)MXD4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14582   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14582  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14582
Splice isoforms : SwissVarQ14582
PhosPhoSitePlusQ14582
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)bHLH_dom   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
Conserved Domain (NCBI)MXD4
DMDM Disease mutations10608
Blocks (Seattle)MXD4
SuperfamilyQ14582
Human Protein AtlasENSG00000123933
Peptide AtlasQ14582
HPRD10103
IPIIPI00031584   IPI00384899   IPI01010306   IPI00171713   IPI00744328   IPI00967107   IPI00966839   
Protein Interaction databases
DIP (DOE-UCLA)Q14582
IntAct (EBI)Q14582
FunCoupENSG00000123933
BioGRIDMXD4
STRING (EMBL)MXD4
ZODIACMXD4
Ontologies - Pathways
QuickGOQ14582
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription corepressor activity  protein binding  nucleus  transcription, DNA-templated  negative regulation of cell proliferation  protein dimerization activity  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription corepressor activity  protein binding  nucleus  transcription, DNA-templated  negative regulation of cell proliferation  protein dimerization activity  
NDEx NetworkMXD4
Atlas of Cancer Signalling NetworkMXD4
Wikipedia pathwaysMXD4
Orthology - Evolution
OrthoDB10608
GeneTree (enSembl)ENSG00000123933
Phylogenetic Trees/Animal Genes : TreeFamMXD4
HOVERGENQ14582
HOGENOMQ14582
Homologs : HomoloGeneMXD4
Homology/Alignments : Family Browser (UCSC)MXD4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMXD4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MXD4
dbVarMXD4
ClinVarMXD4
1000_GenomesMXD4 
Exome Variant ServerMXD4
ExAC (Exome Aggregation Consortium)MXD4 (select the gene name)
Genetic variants : HAPMAP10608
Genomic Variants (DGV)MXD4 [DGVbeta]
DECIPHERMXD4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMXD4 
Mutations
ICGC Data PortalMXD4 
TCGA Data PortalMXD4 
Broad Tumor PortalMXD4
OASIS PortalMXD4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMXD4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMXD4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MXD4
DgiDB (Drug Gene Interaction Database)MXD4
DoCM (Curated mutations)MXD4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MXD4 (select a term)
intoGenMXD4
Cancer3DMXD4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenMXD4
Genetic Testing Registry MXD4
NextProtQ14582 [Medical]
TSGene10608
GENETestsMXD4
Target ValidationMXD4
Huge Navigator MXD4 [HugePedia]
snp3D : Map Gene to Disease10608
BioCentury BCIQMXD4
ClinGenMXD4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10608
Chemical/Pharm GKB GenePA134914966
Clinical trialMXD4
Miscellaneous
canSAR (ICR)MXD4 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMXD4
EVEXMXD4
GoPubMedMXD4
iHOPMXD4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:08:25 CEST 2017

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