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MYF6 (myogenic factor 6)

Identity

Alias_namesmyogenic factor 6 (herculin)
Alias_symbol (synonym)MRF4
bHLHc4
Other aliasCNM3
myf-6
HGNC (Hugo) MYF6
LocusID (NCBI) 4618
Atlas_Id 50237
Location 12q21.31  [Link to chromosome band 12q21]
Location_base_pair Starts at 80707629 and ends at 80709477 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYF6   7566
Cards
Entrez_Gene (NCBI)MYF6  4618  myogenic factor 6
AliasesCNM3; MRF4; bHLHc4; myf-6
GeneCards (Weizmann)MYF6
Ensembl hg19 (Hinxton)ENSG00000111046 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111046 [Gene_View]  chr12:80707629-80709477 [Contig_View]  MYF6 [Vega]
ICGC DataPortalENSG00000111046
TCGA cBioPortalMYF6
AceView (NCBI)MYF6
Genatlas (Paris)MYF6
WikiGenes4618
SOURCE (Princeton)MYF6
Genetics Home Reference (NIH)MYF6
Genomic and cartography
GoldenPath hg38 (UCSC)MYF6  -     chr12:80707629-80709477 +  12q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYF6  -     12q21.31   [Description]    (hg19-Feb_2009)
EnsemblMYF6 - 12q21.31 [CytoView hg19]  MYF6 - 12q21.31 [CytoView hg38]
Mapping of homologs : NCBIMYF6 [Mapview hg19]  MYF6 [Mapview hg38]
OMIM159991   614408   
Gene and transcription
Genbank (Entrez)AA176491 AK313287 BC017834 CR407641 CR541763
RefSeq transcript (Entrez)NM_002469
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYF6
Cluster EST : UnigeneHs.35937 [ NCBI ]
CGAP (NCI)Hs.35937
Alternative Splicing GalleryENSG00000111046
Gene ExpressionMYF6 [ NCBI-GEO ]   MYF6 [ EBI - ARRAY_EXPRESS ]   MYF6 [ SEEK ]   MYF6 [ MEM ]
Gene Expression Viewer (FireBrowse)MYF6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4618
GTEX Portal (Tissue expression)MYF6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23409   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23409  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23409
Splice isoforms : SwissVarP23409
PhosPhoSitePlusP23409
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (EBI)Basic    bHLH_dom   
Domain families : Pfam (Sanger)Basic (PF01586)    HLH (PF00010)   
Domain families : Pfam (NCBI)pfam01586    pfam00010   
Domain families : Smart (EMBL)BASIC (SM00520)  HLH (SM00353)  
Conserved Domain (NCBI)MYF6
DMDM Disease mutations4618
Blocks (Seattle)MYF6
SuperfamilyP23409
Human Protein AtlasENSG00000111046
Peptide AtlasP23409
HPRD01169
IPIIPI00011548   
Protein Interaction databases
DIP (DOE-UCLA)P23409
IntAct (EBI)P23409
FunCoupENSG00000111046
BioGRIDMYF6
STRING (EMBL)MYF6
ZODIACMYF6
Ontologies - Pathways
QuickGOP23409
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  somitogenesis  transcription factor activity, sequence-specific DNA binding  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  skeletal muscle tissue development  skeletal muscle cell differentiation  muscle cell fate commitment  skeletal muscle tissue regeneration  positive regulation of myoblast differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  positive regulation of skeletal muscle fiber development  positive regulation of muscle cell differentiation  muscle tissue morphogenesis  E-box binding  RNA polymerase II transcription factor complex  positive regulation of myoblast fusion  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  somitogenesis  transcription factor activity, sequence-specific DNA binding  transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  nucleoplasm  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  skeletal muscle tissue development  skeletal muscle cell differentiation  muscle cell fate commitment  skeletal muscle tissue regeneration  positive regulation of myoblast differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  positive regulation of skeletal muscle fiber development  positive regulation of muscle cell differentiation  muscle tissue morphogenesis  E-box binding  RNA polymerase II transcription factor complex  positive regulation of myoblast fusion  
NDEx NetworkMYF6
Atlas of Cancer Signalling NetworkMYF6
Wikipedia pathwaysMYF6
Orthology - Evolution
OrthoDB4618
GeneTree (enSembl)ENSG00000111046
Phylogenetic Trees/Animal Genes : TreeFamMYF6
HOVERGENP23409
HOGENOMP23409
Homologs : HomoloGeneMYF6
Homology/Alignments : Family Browser (UCSC)MYF6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYF6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYF6
dbVarMYF6
ClinVarMYF6
1000_GenomesMYF6 
Exome Variant ServerMYF6
ExAC (Exome Aggregation Consortium)MYF6 (select the gene name)
Genetic variants : HAPMAP4618
Genomic Variants (DGV)MYF6 [DGVbeta]
DECIPHERMYF6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYF6 
Mutations
ICGC Data PortalMYF6 
TCGA Data PortalMYF6 
Broad Tumor PortalMYF6
OASIS PortalMYF6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYF6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYF6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYF6
DgiDB (Drug Gene Interaction Database)MYF6
DoCM (Curated mutations)MYF6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYF6 (select a term)
intoGenMYF6
Cancer3DMYF6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM159991    614408   
Orphanet17834    17834   
MedgenMYF6
Genetic Testing Registry MYF6
NextProtP23409 [Medical]
TSGene4618
GENETestsMYF6
Huge Navigator MYF6 [HugePedia]
snp3D : Map Gene to Disease4618
BioCentury BCIQMYF6
ClinGenMYF6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4618
Chemical/Pharm GKB GenePA31364
Clinical trialMYF6
Miscellaneous
canSAR (ICR)MYF6 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYF6
EVEXMYF6
GoPubMedMYF6
iHOPMYF6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:27:38 CEST 2017

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