Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MYH14 (myosin heavy chain 14)

Identity

Alias_namesDFNA4
myosin, heavy polypeptide 14
myosin, heavy chain 14, non-muscle
Alias_symbol (synonym)FLJ13881
KIAA2034
MHC16
MYH17
Other aliasDFNA4A
FP17425
NMHC II-C
NMHC-II-C
PNMHH
myosin
HGNC (Hugo) MYH14
LocusID (NCBI) 79784
Atlas_Id 70608
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 50203628 and ends at 50310544 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MBD6 (12q13.3) / MYH14 (19q13.33)MYH14 (19q13.33) / MBD6 (12q13.3)MYH14 (19q13.33) / MYH14 (19q13.33)
MYH14 (19q13.33) / PLCG1 (20q12)MYH14 (19q13.33) / SEC31B (10q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYH14   23212
Cards
Entrez_Gene (NCBI)MYH14  79784  myosin heavy chain 14
AliasesDFNA4; DFNA4A; FP17425; MHC16; 
MYH17; NMHC; NMHC-II-C; PNMHH; myosin
GeneCards (Weizmann)MYH14
Ensembl hg19 (Hinxton)ENSG00000105357 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105357 [Gene_View]  chr19:50203628-50310544 [Contig_View]  MYH14 [Vega]
ICGC DataPortalENSG00000105357
TCGA cBioPortalMYH14
AceView (NCBI)MYH14
Genatlas (Paris)MYH14
WikiGenes79784
SOURCE (Princeton)MYH14
Genetics Home Reference (NIH)MYH14
Genomic and cartography
GoldenPath hg38 (UCSC)MYH14  -     chr19:50203628-50310544 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYH14  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblMYH14 - 19q13.33 [CytoView hg19]  MYH14 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIMYH14 [Mapview hg19]  MYH14 [Mapview hg38]
OMIM600652   608568   614369   
Gene and transcription
Genbank (Entrez)AB111886 AB290169 AK023943 AK091982 AK122704
RefSeq transcript (Entrez)NM_001077186 NM_001145809 NM_024729
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYH14
Cluster EST : UnigeneHs.467142 [ NCBI ]
CGAP (NCI)Hs.467142
Alternative Splicing GalleryENSG00000105357
Gene ExpressionMYH14 [ NCBI-GEO ]   MYH14 [ EBI - ARRAY_EXPRESS ]   MYH14 [ SEEK ]   MYH14 [ MEM ]
Gene Expression Viewer (FireBrowse)MYH14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79784
GTEX Portal (Tissue expression)MYH14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z406   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z406  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z406
Splice isoforms : SwissVarQ7Z406
PhosPhoSitePlusQ7Z406
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Myosin-like_IQ_dom    Myosin_head_motor_dom    Myosin_N    Myosin_tail    P-loop_NTPase   
Domain families : Pfam (Sanger)Myosin_head (PF00063)    Myosin_N (PF02736)    Myosin_tail_1 (PF01576)   
Domain families : Pfam (NCBI)pfam00063    pfam02736    pfam01576   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  
Conserved Domain (NCBI)MYH14
DMDM Disease mutations79784
Blocks (Seattle)MYH14
PDB (SRS)5JLH   
PDB (PDBSum)5JLH   
PDB (IMB)5JLH   
PDB (RSDB)5JLH   
Structural Biology KnowledgeBase5JLH   
SCOP (Structural Classification of Proteins)5JLH   
CATH (Classification of proteins structures)5JLH   
SuperfamilyQ7Z406
Human Protein AtlasENSG00000105357
Peptide AtlasQ7Z406
HPRD10543
IPIIPI00337335   IPI00941217   IPI00607778   IPI00029818   IPI00607818   IPI01017884   IPI01017917   IPI01012558   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z406
IntAct (EBI)Q7Z406
FunCoupENSG00000105357
BioGRIDMYH14
STRING (EMBL)MYH14
ZODIACMYH14
Ontologies - Pathways
QuickGOQ7Z406
Ontology : AmiGOmicrofilament motor activity  stress fiber  skeletal muscle contraction  calmodulin binding  ATP binding  cytosol  brush border  skeletal muscle tissue development  sensory perception of sound  regulation of cell shape  membrane  myosin II complex  ATPase activity  neuronal action potential  actin filament-based movement  axon  growth cone  actin-dependent ATPase activity  actomyosin structure organization  actomyosin  myelin sheath  actin filament binding  extracellular exosome  mitochondrion morphogenesis  vocalization behavior  myosin II filament  
Ontology : EGO-EBImicrofilament motor activity  stress fiber  skeletal muscle contraction  calmodulin binding  ATP binding  cytosol  brush border  skeletal muscle tissue development  sensory perception of sound  regulation of cell shape  membrane  myosin II complex  ATPase activity  neuronal action potential  actin filament-based movement  axon  growth cone  actin-dependent ATPase activity  actomyosin structure organization  actomyosin  myelin sheath  actin filament binding  extracellular exosome  mitochondrion morphogenesis  vocalization behavior  myosin II filament  
Pathways : KEGGTight junction    Regulation of actin cytoskeleton    Salmonella infection   
NDEx NetworkMYH14
Atlas of Cancer Signalling NetworkMYH14
Wikipedia pathwaysMYH14
Orthology - Evolution
OrthoDB79784
GeneTree (enSembl)ENSG00000105357
Phylogenetic Trees/Animal Genes : TreeFamMYH14
HOVERGENQ7Z406
HOGENOMQ7Z406
Homologs : HomoloGeneMYH14
Homology/Alignments : Family Browser (UCSC)MYH14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYH14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYH14
dbVarMYH14
ClinVarMYH14
1000_GenomesMYH14 
Exome Variant ServerMYH14
ExAC (Exome Aggregation Consortium)MYH14 (select the gene name)
Genetic variants : HAPMAP79784
Genomic Variants (DGV)MYH14 [DGVbeta]
DECIPHERMYH14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYH14 
Mutations
ICGC Data PortalMYH14 
TCGA Data PortalMYH14 
Broad Tumor PortalMYH14
OASIS PortalMYH14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYH14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYH14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MYH14
DgiDB (Drug Gene Interaction Database)MYH14
DoCM (Curated mutations)MYH14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYH14 (select a term)
intoGenMYH14
Cancer3DMYH14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600652    608568    614369   
Orphanet22698    12046   
MedgenMYH14
Genetic Testing Registry MYH14
NextProtQ7Z406 [Medical]
TSGene79784
GENETestsMYH14
Target ValidationMYH14
Huge Navigator MYH14 [HugePedia]
snp3D : Map Gene to Disease79784
BioCentury BCIQMYH14
ClinGenMYH14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79784
Chemical/Pharm GKB GenePA134935217
Clinical trialMYH14
Miscellaneous
canSAR (ICR)MYH14 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYH14
EVEXMYH14
GoPubMedMYH14
iHOPMYH14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:31:34 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.