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MYH7B (myosin heavy chain 7B)

Identity

Alias_namesmyosin, heavy polypeptide 7B, cardiac muscle, beta
Alias_symbol (synonym)KIAA1512
dJ756N5.1
MYH14
MHC14
Other alias
HGNC (Hugo) MYH7B
LocusID (NCBI) 57644
Atlas_Id 70610
Location 20q11.22  [Link to chromosome band 20q11]
Location_base_pair Starts at 34955835 and ends at 35002437 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACSF3 (16q24.3) / MYH7B (20q11.22)MYH7B (20q11.22) / PPFIBP1 (12p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYH7B   15906
Cards
Entrez_Gene (NCBI)MYH7B  57644  myosin heavy chain 7B
AliasesMHC14; MYH14
GeneCards (Weizmann)MYH7B
Ensembl hg19 (Hinxton)ENSG00000078814 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000078814 [Gene_View]  chr20:34955835-35002437 [Contig_View]  MYH7B [Vega]
ICGC DataPortalENSG00000078814
TCGA cBioPortalMYH7B
AceView (NCBI)MYH7B
Genatlas (Paris)MYH7B
WikiGenes57644
SOURCE (Princeton)MYH7B
Genetics Home Reference (NIH)MYH7B
Genomic and cartography
GoldenPath hg38 (UCSC)MYH7B  -     chr20:34955835-35002437 +  20q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYH7B  -     20q11.22   [Description]    (hg19-Feb_2009)
EnsemblMYH7B - 20q11.22 [CytoView hg19]  MYH7B - 20q11.22 [CytoView hg38]
Mapping of homologs : NCBIMYH7B [Mapview hg19]  MYH7B [Mapview hg38]
OMIM609928   
Gene and transcription
Genbank (Entrez)AB040945 AK000947 BC007808 BC069327 BC069406
RefSeq transcript (Entrez)NM_020884
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYH7B
Cluster EST : UnigeneHs.414122 [ NCBI ]
CGAP (NCI)Hs.414122
Alternative Splicing GalleryENSG00000078814
Gene ExpressionMYH7B [ NCBI-GEO ]   MYH7B [ EBI - ARRAY_EXPRESS ]   MYH7B [ SEEK ]   MYH7B [ MEM ]
Gene Expression Viewer (FireBrowse)MYH7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57644
GTEX Portal (Tissue expression)MYH7B
Human Protein AtlasENSG00000078814-MYH7B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA7E2Y1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA7E2Y1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA7E2Y1
Splice isoforms : SwissVarA7E2Y1
PhosPhoSitePlusA7E2Y1
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Myosin-like_IQ_dom    Myosin_head_motor_dom    Myosin_N    Myosin_tail    P-loop_NTPase   
Domain families : Pfam (Sanger)Myosin_head (PF00063)    Myosin_N (PF02736)    Myosin_tail_1 (PF01576)   
Domain families : Pfam (NCBI)pfam00063    pfam02736    pfam01576   
Domain families : Smart (EMBL)MYSc (SM00242)  
Conserved Domain (NCBI)MYH7B
DMDM Disease mutations57644
Blocks (Seattle)MYH7B
SuperfamilyA7E2Y1
Human Protein Atlas [tissue]ENSG00000078814-MYH7B [tissue]
Peptide AtlasA7E2Y1
HPRD11379
IPIIPI00903322   IPI00903131   IPI00642716   IPI00552823   IPI00553094   IPI00552157   IPI00647671   IPI00552434   
Protein Interaction databases
DIP (DOE-UCLA)A7E2Y1
IntAct (EBI)A7E2Y1
FunCoupENSG00000078814
BioGRIDMYH7B
STRING (EMBL)MYH7B
ZODIACMYH7B
Ontologies - Pathways
QuickGOA7E2Y1
Ontology : AmiGOmotor activity  actin binding  protein binding  ATP binding  membrane  myosin filament  cardiac myofibril  
Ontology : EGO-EBImotor activity  actin binding  protein binding  ATP binding  membrane  myosin filament  cardiac myofibril  
Pathways : KEGGTight junction   
NDEx NetworkMYH7B
Atlas of Cancer Signalling NetworkMYH7B
Wikipedia pathwaysMYH7B
Orthology - Evolution
OrthoDB57644
GeneTree (enSembl)ENSG00000078814
Phylogenetic Trees/Animal Genes : TreeFamMYH7B
HOVERGENA7E2Y1
HOGENOMA7E2Y1
Homologs : HomoloGeneMYH7B
Homology/Alignments : Family Browser (UCSC)MYH7B
Gene fusions - Rearrangements
Tumor Fusion PortalMYH7B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYH7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYH7B
dbVarMYH7B
ClinVarMYH7B
1000_GenomesMYH7B 
Exome Variant ServerMYH7B
ExAC (Exome Aggregation Consortium)ENSG00000078814
GNOMAD BrowserENSG00000078814
Genetic variants : HAPMAP57644
Genomic Variants (DGV)MYH7B [DGVbeta]
DECIPHERMYH7B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYH7B 
Mutations
ICGC Data PortalMYH7B 
TCGA Data PortalMYH7B 
Broad Tumor PortalMYH7B
OASIS PortalMYH7B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYH7B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYH7B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYH7B
DgiDB (Drug Gene Interaction Database)MYH7B
DoCM (Curated mutations)MYH7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYH7B (select a term)
intoGenMYH7B
Cancer3DMYH7B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609928   
Orphanet10750   
DisGeNETMYH7B
MedgenMYH7B
Genetic Testing Registry MYH7B
NextProtA7E2Y1 [Medical]
TSGene57644
GENETestsMYH7B
Target ValidationMYH7B
Huge Navigator MYH7B [HugePedia]
snp3D : Map Gene to Disease57644
BioCentury BCIQMYH7B
ClinGenMYH7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57644
Chemical/Pharm GKB GenePA31375
Clinical trialMYH7B
Miscellaneous
canSAR (ICR)MYH7B (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYH7B
EVEXMYH7B
GoPubMedMYH7B
iHOPMYH7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:42:00 CET 2017

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