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MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal)

Identity

Alias_namesmyosin
Alias_symbol (synonym)MyHC-peri
MyHC-pn
Other aliasDA7
gtMHC-F
HGNC (Hugo) MYH8
LocusID (NCBI) 4626
Atlas_Id 53848
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 10293642 and ends at 10325267 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYH8   7578
Cards
Entrez_Gene (NCBI)MYH8  4626  myosin, heavy chain 8, skeletal muscle, perinatal
AliasesDA7; MyHC-peri; MyHC-pn; gtMHC-F
GeneCards (Weizmann)MYH8
Ensembl hg19 (Hinxton)ENSG00000133020 [Gene_View]  chr17:10293642-10325267 [Contig_View]  MYH8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000133020 [Gene_View]  chr17:10293642-10325267 [Contig_View]  MYH8 [Vega]
ICGC DataPortalENSG00000133020
TCGA cBioPortalMYH8
AceView (NCBI)MYH8
Genatlas (Paris)MYH8
WikiGenes4626
SOURCE (Princeton)MYH8
Genetics Home Reference (NIH)MYH8
Genomic and cartography
GoldenPath hg19 (UCSC)MYH8  -     chr17:10293642-10325267 -  17p13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MYH8  -     17p13.1   [Description]    (hg38-Dec_2013)
EnsemblMYH8 - 17p13.1 [CytoView hg19]  MYH8 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBIMYH8 [Mapview hg19]  MYH8 [Mapview hg38]
OMIM158300   160741   608837   
Gene and transcription
Genbank (Entrez)AK303395 BC172386 DB142109 M36769 X51592
RefSeq transcript (Entrez)NM_002472
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_013015 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)MYH8
Cluster EST : UnigeneHs.700484 [ NCBI ]
CGAP (NCI)Hs.700484
Alternative Splicing GalleryENSG00000133020
Gene ExpressionMYH8 [ NCBI-GEO ]   MYH8 [ EBI - ARRAY_EXPRESS ]   MYH8 [ SEEK ]   MYH8 [ MEM ]
Gene Expression Viewer (FireBrowse)MYH8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4626
GTEX Portal (Tissue expression)MYH8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13535   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13535  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13535
Splice isoforms : SwissVarP13535
PhosPhoSitePlusP13535
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Myosin-like_IQ_dom    Myosin_head_motor_dom    Myosin_N    Myosin_tail    P-loop_NTPase   
Domain families : Pfam (Sanger)Myosin_head (PF00063)    Myosin_N (PF02736)    Myosin_tail_1 (PF01576)   
Domain families : Pfam (NCBI)pfam00063    pfam02736    pfam01576   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  
Conserved Domain (NCBI)MYH8
DMDM Disease mutations4626
Blocks (Seattle)MYH8
SuperfamilyP13535
Human Protein AtlasENSG00000133020
Peptide AtlasP13535
HPRD11760
IPIIPI00302329   
Protein Interaction databases
DIP (DOE-UCLA)P13535
IntAct (EBI)P13535
FunCoupENSG00000133020
BioGRIDMYH8
STRING (EMBL)MYH8
ZODIACMYH8
Ontologies - Pathways
QuickGOP13535
Ontology : AmiGOmicrofilament motor activity  skeletal muscle contraction  calmodulin binding  ATP binding  cytoplasm  cytosol  muscle myosin complex  protein dephosphorylation  muscle contraction  structural constituent of muscle  ATPase activity  myosin phosphatase activity  sarcomere  muscle filament sliding  muscle filament sliding  myosin light chain binding  myosin filament  ATP metabolic process  actin filament binding  
Ontology : EGO-EBImicrofilament motor activity  skeletal muscle contraction  calmodulin binding  ATP binding  cytoplasm  cytosol  muscle myosin complex  protein dephosphorylation  muscle contraction  structural constituent of muscle  ATPase activity  myosin phosphatase activity  sarcomere  muscle filament sliding  muscle filament sliding  myosin light chain binding  myosin filament  ATP metabolic process  actin filament binding  
Pathways : KEGGTight junction   
NDEx NetworkMYH8
Atlas of Cancer Signalling NetworkMYH8
Wikipedia pathwaysMYH8
Orthology - Evolution
OrthoDB4626
GeneTree (enSembl)ENSG00000133020
Phylogenetic Trees/Animal Genes : TreeFamMYH8
HOVERGENP13535
HOGENOMP13535
Homologs : HomoloGeneMYH8
Homology/Alignments : Family Browser (UCSC)MYH8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYH8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYH8
dbVarMYH8
ClinVarMYH8
1000_GenomesMYH8 
Exome Variant ServerMYH8
ExAC (Exome Aggregation Consortium)MYH8 (select the gene name)
Genetic variants : HAPMAP4626
Genomic Variants (DGV)MYH8 [DGVbeta]
DECIPHER (Syndromes)17:10293642-10325267  ENSG00000133020
CONAN: Copy Number AnalysisMYH8 
Mutations
ICGC Data PortalMYH8 
TCGA Data PortalMYH8 
Broad Tumor PortalMYH8
OASIS PortalMYH8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYH8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYH8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYH8
DgiDB (Drug Gene Interaction Database)MYH8
DoCM (Curated mutations)MYH8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYH8 (select a term)
intoGenMYH8
Cancer3DMYH8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM158300    160741    608837   
Orphanet2990    21650   
MedgenMYH8
Genetic Testing Registry MYH8
NextProtP13535 [Medical]
TSGene4626
GENETestsMYH8
Huge Navigator MYH8 [HugePedia]
snp3D : Map Gene to Disease4626
BioCentury BCIQMYH8
ClinGenMYH8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4626
Chemical/Pharm GKB GenePA31376
Clinical trialMYH8
Miscellaneous
canSAR (ICR)MYH8 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYH8
EVEXMYH8
GoPubMedMYH8
iHOPMYH8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:17:50 CET 2017

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