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MYL1 (myosin light chain 1)

Identity

Alias (NCBI)MLC1F
MLC3F
MYOFTA
HGNC (Hugo) MYL1
HGNC Previous namemyosin, light polypeptide 1, alkali; skeletal, fast
 myosin, light chain 1, alkali; skeletal, fast
LocusID (NCBI) 4632
Atlas_Id 50200
Location 2q34  [Link to chromosome band 2q34]
Location_base_pair Starts at 210290150 and ends at 210303615 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MYL1 (2q34) / TGFBR2 (3p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MYL1   7582
Cards
Entrez_Gene (NCBI)MYL1    myosin light chain 1
AliasesMLC1F; MLC3F; MYOFTA
GeneCards (Weizmann)MYL1
Ensembl hg19 (Hinxton)ENSG00000168530 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168530 [Gene_View]  ENSG00000168530 [Sequence]  chr2:210290150-210303615 [Contig_View]  MYL1 [Vega]
ICGC DataPortalENSG00000168530
TCGA cBioPortalMYL1
AceView (NCBI)MYL1
Genatlas (Paris)MYL1
SOURCE (Princeton)MYL1
Genetics Home Reference (NIH)MYL1
Genomic and cartography
GoldenPath hg38 (UCSC)MYL1  -     chr2:210290150-210303615 -  2q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYL1  -     2q34   [Description]    (hg19-Feb_2009)
GoldenPathMYL1 - 2q34 [CytoView hg19]  MYL1 - 2q34 [CytoView hg38]
ImmunoBaseENSG00000168530
genome Data Viewer NCBIMYL1 [Mapview hg19]  
OMIM160780   618414   
Gene and transcription
Genbank (Entrez)AA705167 AK311892 AK311942 BC005318 CR456869
RefSeq transcript (Entrez)NM_079420 NM_079422
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYL1
Alternative Splicing GalleryENSG00000168530
Gene ExpressionMYL1 [ NCBI-GEO ]   MYL1 [ EBI - ARRAY_EXPRESS ]   MYL1 [ SEEK ]   MYL1 [ MEM ]
Gene Expression Viewer (FireBrowse)MYL1 [ Firebrowse - Broad ]
GenevisibleExpression of MYL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4632
GTEX Portal (Tissue expression)MYL1
Human Protein AtlasENSG00000168530-MYL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05976   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05976  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05976
Splice isoforms : SwissVarP05976
PhosPhoSitePlusP05976
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_6 (PF13405)   
Domain families : Pfam (NCBI)pfam13405   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)MYL1
Blocks (Seattle)MYL1
SuperfamilyP05976
Human Protein Atlas [tissue]ENSG00000168530-MYL1 [tissue]
Peptide AtlasP05976
HPRD01180
IPIIPI00216070   IPI00220332   
Protein Interaction databases
DIP (DOE-UCLA)P05976
IntAct (EBI)P05976
BioGRIDMYL1
STRING (EMBL)MYL1
ZODIACMYL1
Ontologies - Pathways
QuickGOP05976
Ontology : AmiGOcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  structural constituent of muscle  structural constituent of muscle  myofibril  sarcomere  muscle filament sliding  muscle filament sliding  cardiac muscle contraction  
Ontology : EGO-EBIcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  structural constituent of muscle  structural constituent of muscle  myofibril  sarcomere  muscle filament sliding  muscle filament sliding  cardiac muscle contraction  
NDEx NetworkMYL1
Atlas of Cancer Signalling NetworkMYL1
Wikipedia pathwaysMYL1
Orthology - Evolution
OrthoDB4632
GeneTree (enSembl)ENSG00000168530
Phylogenetic Trees/Animal Genes : TreeFamMYL1
HOGENOMP05976
Homologs : HomoloGeneMYL1
Homology/Alignments : Family Browser (UCSC)MYL1
Gene fusions - Rearrangements
Fusion : QuiverMYL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYL1 [hg38]
dbVarMYL1
ClinVarMYL1
MonarchMYL1
1000_GenomesMYL1 
Exome Variant ServerMYL1
GNOMAD BrowserENSG00000168530
Varsome BrowserMYL1
Genomic Variants (DGV)MYL1 [DGVbeta]
DECIPHERMYL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYL1 
Mutations
ICGC Data PortalMYL1 
TCGA Data PortalMYL1 
Broad Tumor PortalMYL1
OASIS PortalMYL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMYL1
Mutations and Diseases : HGMDMYL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYL1
DgiDB (Drug Gene Interaction Database)MYL1
DoCM (Curated mutations)MYL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYL1 (select a term)
intoGenMYL1
Cancer3DMYL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM160780    618414   
Orphanet
DisGeNETMYL1
MedgenMYL1
Genetic Testing Registry MYL1
NextProtP05976 [Medical]
GENETestsMYL1
Target ValidationMYL1
Huge Navigator MYL1 [HugePedia]
ClinGenMYL1
Clinical trials, drugs, therapy
MyCancerGenomeMYL1
Protein Interactions : CTD
Pharm GKB GenePA31379
PharosP05976
Clinical trialMYL1
Miscellaneous
canSAR (ICR)MYL1 (select the gene name)
HarmonizomeMYL1
DataMed IndexMYL1
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMYL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:27:53 CET 2021
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