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MYL1 (myosin light chain 1)

Identity

Other namesMLC1F
MLC3F
HGNC (Hugo) MYL1
LocusID (NCBI) 4632
Atlas_Id 50200
Location 2q34  [Link to chromosome band 2q34]
Location_base_pair Starts at 211154868 and ends at 211179895 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MYL1 (2q34) / TGFBR2 (3p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYL1   7582
Cards
Entrez_Gene (NCBI)MYL1  4632  myosin light chain 1
AliasesMLC1F; MLC3F
GeneCards (Weizmann)MYL1
Ensembl hg19 (Hinxton)ENSG00000168530 [Gene_View]  chr2:211154868-211179895 [Contig_View]  MYL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168530 [Gene_View]  chr2:211154868-211179895 [Contig_View]  MYL1 [Vega]
ICGC DataPortalENSG00000168530
TCGA cBioPortalMYL1
AceView (NCBI)MYL1
Genatlas (Paris)MYL1
WikiGenes4632
SOURCE (Princeton)MYL1
Genomic and cartography
GoldenPath hg19 (UCSC)MYL1  -     chr2:211154868-211179895 -  2q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MYL1  -     2q34   [Description]    (hg38-Dec_2013)
EnsemblMYL1 - 2q34 [CytoView hg19]  MYL1 - 2q34 [CytoView hg38]
Mapping of homologs : NCBIMYL1 [Mapview hg19]  MYL1 [Mapview hg38]
OMIM160780   
Gene and transcription
Genbank (Entrez)AA705167 AK311892 AK311942 BC005318 CR456869
RefSeq transcript (Entrez)NM_079420 NM_079422
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)MYL1
Cluster EST : UnigeneHs.187338 [ NCBI ]
CGAP (NCI)Hs.187338
Alternative Splicing GalleryENSG00000168530
Gene ExpressionMYL1 [ NCBI-GEO ]   MYL1 [ EBI - ARRAY_EXPRESS ]   MYL1 [ SEEK ]   MYL1 [ MEM ]
Gene Expression Viewer (FireBrowse)MYL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4632
GTEX Portal (Tissue expression)MYL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05976 (Uniprot)
NextProtP05976  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05976
Splice isoforms : SwissVarP05976 (Swissvar)
PhosPhoSitePlusP05976
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_6 (PF13405)   
Domain families : Pfam (NCBI)pfam13405   
Domain families : Smart (EMBL)EFh (SM00054)  
DMDM Disease mutations4632
Blocks (Seattle)MYL1
SuperfamilyP05976
Human Protein AtlasENSG00000168530
Peptide AtlasP05976
HPRD01180
IPIIPI00216070   IPI00220332   
Protein Interaction databases
DIP (DOE-UCLA)P05976
IntAct (EBI)P05976
FunCoupENSG00000168530
BioGRIDMYL1
STRING (EMBL)MYL1
ZODIACMYL1
Ontologies - Pathways
QuickGOP05976
Ontology : AmiGOcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  structural constituent of muscle  myofibril  sarcomere  muscle filament sliding  muscle filament sliding  cardiac muscle contraction  
Ontology : EGO-EBIcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  structural constituent of muscle  myofibril  sarcomere  muscle filament sliding  muscle filament sliding  cardiac muscle contraction  
NDEx Network
Atlas of Cancer Signalling NetworkMYL1
Wikipedia pathwaysMYL1
Orthology - Evolution
OrthoDB4632
GeneTree (enSembl)ENSG00000168530
Phylogenetic Trees/Animal Genes : TreeFamMYL1
Homologs : HomoloGeneMYL1
Homology/Alignments : Family Browser (UCSC)MYL1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerMYL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYL1
dbVarMYL1
ClinVarMYL1
1000_GenomesMYL1 
Exome Variant ServerMYL1
ExAC (Exome Aggregation Consortium)MYL1 (select the gene name)
Genetic variants : HAPMAP4632
Genomic Variants (DGV)MYL1 [DGVbeta]
Mutations
ICGC Data PortalMYL1 
TCGA Data PortalMYL1 
Broad Tumor PortalMYL1
OASIS PortalMYL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYL1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYL1
DgiDB (Drug Gene Interaction Database)MYL1
DoCM (Curated mutations)MYL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYL1 (select a term)
intoGenMYL1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:211154868-211179895  ENSG00000168530
CONAN: Copy Number AnalysisMYL1 
Mutations and Diseases : HGMDMYL1
OMIM160780   
MedgenMYL1
Genetic Testing Registry MYL1
NextProtP05976 [Medical]
TSGene4632
GENETestsMYL1
Huge Navigator MYL1 [HugePedia]
snp3D : Map Gene to Disease4632
BioCentury BCIQMYL1
ClinGenMYL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4632
Chemical/Pharm GKB GenePA31379
Clinical trialMYL1
Miscellaneous
canSAR (ICR)MYL1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYL1
EVEXMYL1
GoPubMedMYL1
iHOPMYL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:06:01 CEST 2016

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