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MYL5 (myosin light chain 5)

Identity

Alias_namesmyosin, light polypeptide 5, regulatory
myosin, light chain 5, regulatory
Other alias-
HGNC (Hugo) MYL5
LocusID (NCBI) 4636
Atlas_Id 70615
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 677922 and ends at 682028 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GAK (4p16.3) / MYL5 (4p16.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYL5   7586
Cards
Entrez_Gene (NCBI)MYL5  4636  myosin light chain 5
Aliases
GeneCards (Weizmann)MYL5
Ensembl hg19 (Hinxton)ENSG00000215375 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000215375 [Gene_View]  chr4:677922-682028 [Contig_View]  MYL5 [Vega]
ICGC DataPortalENSG00000215375
TCGA cBioPortalMYL5
AceView (NCBI)MYL5
Genatlas (Paris)MYL5
WikiGenes4636
SOURCE (Princeton)MYL5
Genetics Home Reference (NIH)MYL5
Genomic and cartography
GoldenPath hg38 (UCSC)MYL5  -     chr4:677922-682028 +  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYL5  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblMYL5 - 4p16.3 [CytoView hg19]  MYL5 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIMYL5 [Mapview hg19]  MYL5 [Mapview hg38]
OMIM160782   
Gene and transcription
Genbank (Entrez)AK123974 AK125529 BC040050 L03785
RefSeq transcript (Entrez)NM_002477
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYL5
Cluster EST : UnigeneHs.410970 [ NCBI ]
CGAP (NCI)Hs.410970
Alternative Splicing GalleryENSG00000215375
Gene ExpressionMYL5 [ NCBI-GEO ]   MYL5 [ EBI - ARRAY_EXPRESS ]   MYL5 [ SEEK ]   MYL5 [ MEM ]
Gene Expression Viewer (FireBrowse)MYL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4636
GTEX Portal (Tissue expression)MYL5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02045   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02045  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02045
Splice isoforms : SwissVarQ02045
PhosPhoSitePlusQ02045
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_6 (PF13405)   
Domain families : Pfam (NCBI)pfam13405   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)MYL5
DMDM Disease mutations4636
Blocks (Seattle)MYL5
SuperfamilyQ02045
Human Protein AtlasENSG00000215375
Peptide AtlasQ02045
HPRD01182
IPIIPI00293380   IPI00847724   IPI00967301   IPI00964443   IPI00965807   
Protein Interaction databases
DIP (DOE-UCLA)Q02045
IntAct (EBI)Q02045
FunCoupENSG00000215375
BioGRIDMYL5
STRING (EMBL)MYL5
ZODIACMYL5
Ontologies - Pathways
QuickGOQ02045
Ontology : AmiGOcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  regulation of muscle contraction  structural constituent of muscle  
Ontology : EGO-EBIcalcium ion binding  cytosol  muscle myosin complex  muscle contraction  regulation of muscle contraction  structural constituent of muscle  
Pathways : KEGGFocal adhesion    Tight junction    Leukocyte transendothelial migration    Regulation of actin cytoskeleton   
NDEx NetworkMYL5
Atlas of Cancer Signalling NetworkMYL5
Wikipedia pathwaysMYL5
Orthology - Evolution
OrthoDB4636
GeneTree (enSembl)ENSG00000215375
Phylogenetic Trees/Animal Genes : TreeFamMYL5
HOVERGENQ02045
HOGENOMQ02045
Homologs : HomoloGeneMYL5
Homology/Alignments : Family Browser (UCSC)MYL5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYL5
dbVarMYL5
ClinVarMYL5
1000_GenomesMYL5 
Exome Variant ServerMYL5
ExAC (Exome Aggregation Consortium)MYL5 (select the gene name)
Genetic variants : HAPMAP4636
Genomic Variants (DGV)MYL5 [DGVbeta]
DECIPHERMYL5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYL5 
Mutations
ICGC Data PortalMYL5 
TCGA Data PortalMYL5 
Broad Tumor PortalMYL5
OASIS PortalMYL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYL5
DgiDB (Drug Gene Interaction Database)MYL5
DoCM (Curated mutations)MYL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYL5 (select a term)
intoGenMYL5
Cancer3DMYL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM160782   
Orphanet
MedgenMYL5
Genetic Testing Registry MYL5
NextProtQ02045 [Medical]
TSGene4636
GENETestsMYL5
Target ValidationMYL5
Huge Navigator MYL5 [HugePedia]
snp3D : Map Gene to Disease4636
BioCentury BCIQMYL5
ClinGenMYL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4636
Chemical/Pharm GKB GenePA31383
Clinical trialMYL5
Miscellaneous
canSAR (ICR)MYL5 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYL5
EVEXMYL5
GoPubMedMYL5
iHOPMYL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:31:35 CEST 2017

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