Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MYLPF (myosin light chain, phosphorylatable, fast skeletal muscle)

Identity

Alias_symbol (synonym)MRLC2
HUMMLC2B
MYL11
Other aliasMLC2B
HGNC (Hugo) MYLPF
LocusID (NCBI) 29895
Atlas_Id 70623
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 30372318 and ends at 30377991 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCO2 (11q23.1) / MYLPF (16p11.2)MYLPF (16p11.2) / BCO2 (11q23.1)MYLPF (16p11.2) / HBG1 (11p15.4)
MYLPF (16p11.2) / TCF4 (18q21.2)SBF1 (22q13.33) / MYLPF (16p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYLPF   29824
Cards
Entrez_Gene (NCBI)MYLPF  29895  myosin light chain, phosphorylatable, fast skeletal muscle
AliasesHUMMLC2B; MLC2B; MRLC2; MYL11
GeneCards (Weizmann)MYLPF
Ensembl hg19 (Hinxton)ENSG00000180209 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180209 [Gene_View]  chr16:30372318-30377991 [Contig_View]  MYLPF [Vega]
ICGC DataPortalENSG00000180209
TCGA cBioPortalMYLPF
AceView (NCBI)MYLPF
Genatlas (Paris)MYLPF
WikiGenes29895
SOURCE (Princeton)MYLPF
Genetics Home Reference (NIH)MYLPF
Genomic and cartography
GoldenPath hg38 (UCSC)MYLPF  -     chr16:30372318-30377991 +  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYLPF  -     16p11.2   [Description]    (hg19-Feb_2009)
EnsemblMYLPF - 16p11.2 [CytoView hg19]  MYLPF - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBIMYLPF [Mapview hg19]  MYLPF [Mapview hg38]
OMIM617378   
Gene and transcription
Genbank (Entrez)AA662706 AF363061 AK314082 BC012571 BI828249
RefSeq transcript (Entrez)NM_001324458 NM_001324459 NM_013292
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYLPF
Cluster EST : UnigeneHs.50889 [ NCBI ]
CGAP (NCI)Hs.50889
Alternative Splicing GalleryENSG00000180209
Gene ExpressionMYLPF [ NCBI-GEO ]   MYLPF [ EBI - ARRAY_EXPRESS ]   MYLPF [ SEEK ]   MYLPF [ MEM ]
Gene Expression Viewer (FireBrowse)MYLPF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29895
GTEX Portal (Tissue expression)MYLPF
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96A32   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96A32  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96A32
Splice isoforms : SwissVarQ96A32
PhosPhoSitePlusQ96A32
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_6 (PF13405)   
Domain families : Pfam (NCBI)pfam13405   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)MYLPF
DMDM Disease mutations29895
Blocks (Seattle)MYLPF
SuperfamilyQ96A32
Human Protein AtlasENSG00000180209
Peptide AtlasQ96A32
HPRD13721
IPIIPI00002352   
Protein Interaction databases
DIP (DOE-UCLA)Q96A32
IntAct (EBI)Q96A32
FunCoupENSG00000180209
BioGRIDMYLPF
STRING (EMBL)MYLPF
ZODIACMYLPF
Ontologies - Pathways
QuickGOQ96A32
Ontology : AmiGOcalcium ion binding  lysosomal membrane  cytosol  muscle myosin complex  muscle contraction  immune response  skeletal muscle tissue development  structural constituent of muscle  
Ontology : EGO-EBIcalcium ion binding  lysosomal membrane  cytosol  muscle myosin complex  muscle contraction  immune response  skeletal muscle tissue development  structural constituent of muscle  
Pathways : KEGGFocal adhesion    Tight junction    Leukocyte transendothelial migration    Regulation of actin cytoskeleton   
NDEx NetworkMYLPF
Atlas of Cancer Signalling NetworkMYLPF
Wikipedia pathwaysMYLPF
Orthology - Evolution
OrthoDB29895
GeneTree (enSembl)ENSG00000180209
Phylogenetic Trees/Animal Genes : TreeFamMYLPF
HOVERGENQ96A32
HOGENOMQ96A32
Homologs : HomoloGeneMYLPF
Homology/Alignments : Family Browser (UCSC)MYLPF
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYLPF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYLPF
dbVarMYLPF
ClinVarMYLPF
1000_GenomesMYLPF 
Exome Variant ServerMYLPF
ExAC (Exome Aggregation Consortium)MYLPF (select the gene name)
Genetic variants : HAPMAP29895
Genomic Variants (DGV)MYLPF [DGVbeta]
DECIPHERMYLPF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYLPF 
Mutations
ICGC Data PortalMYLPF 
TCGA Data PortalMYLPF 
Broad Tumor PortalMYLPF
OASIS PortalMYLPF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYLPF  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYLPF
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYLPF
DgiDB (Drug Gene Interaction Database)MYLPF
DoCM (Curated mutations)MYLPF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYLPF (select a term)
intoGenMYLPF
Cancer3DMYLPF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617378   
Orphanet
MedgenMYLPF
Genetic Testing Registry MYLPF
NextProtQ96A32 [Medical]
TSGene29895
GENETestsMYLPF
Target ValidationMYLPF
Huge Navigator MYLPF [HugePedia]
snp3D : Map Gene to Disease29895
BioCentury BCIQMYLPF
ClinGenMYLPF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29895
Chemical/Pharm GKB GenePA164723287
Clinical trialMYLPF
Miscellaneous
canSAR (ICR)MYLPF (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYLPF
EVEXMYLPF
GoPubMedMYLPF
iHOPMYLPF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:32:04 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.