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MYO15A (myosin XVA)

Identity

Alias_namesDFNB3
MYO15
Other alias
HGNC (Hugo) MYO15A
LocusID (NCBI) 51168
Atlas_Id 70625
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 18012020 and ends at 18083116 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACTN4 (19q13.2) / MYO15A (17p11.2)MYO15A (17p11.2) / TOP3A (17p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO15A   7594
Cards
Entrez_Gene (NCBI)MYO15A  51168  myosin XVA
AliasesDFNB3; MYO15
GeneCards (Weizmann)MYO15A
Ensembl hg19 (Hinxton)ENSG00000091536 [Gene_View]  chr17:18012020-18083116 [Contig_View]  MYO15A [Vega]
Ensembl hg38 (Hinxton)ENSG00000091536 [Gene_View]  chr17:18012020-18083116 [Contig_View]  MYO15A [Vega]
ICGC DataPortalENSG00000091536
TCGA cBioPortalMYO15A
AceView (NCBI)MYO15A
Genatlas (Paris)MYO15A
WikiGenes51168
SOURCE (Princeton)MYO15A
Genetics Home Reference (NIH)MYO15A
Genomic and cartography
GoldenPath hg19 (UCSC)MYO15A  -     chr17:18012020-18083116 +  17p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MYO15A  -     17p11.2   [Description]    (hg38-Dec_2013)
EnsemblMYO15A - 17p11.2 [CytoView hg19]  MYO15A - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBIMYO15A [Mapview hg19]  MYO15A [Mapview hg38]
OMIM600316   602666   
Gene and transcription
Genbank (Entrez)AB209423 AF144094 AK055873 AK294036 AK297179
RefSeq transcript (Entrez)NM_016239
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_011634 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)MYO15A
Cluster EST : UnigeneHs.462390 [ NCBI ]
CGAP (NCI)Hs.462390
Alternative Splicing GalleryENSG00000091536
Gene ExpressionMYO15A [ NCBI-GEO ]   MYO15A [ EBI - ARRAY_EXPRESS ]   MYO15A [ SEEK ]   MYO15A [ MEM ]
Gene Expression Viewer (FireBrowse)MYO15A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51168
GTEX Portal (Tissue expression)MYO15A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKN7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKN7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKN7
Splice isoforms : SwissVarQ9UKN7
PhosPhoSitePlusQ9UKN7
Domaine pattern : Prosite (Expaxy)FERM_3 (PS50057)    IQ (PS50096)    MYOSIN_MOTOR (PS51456)    MYTH4 (PS51016)   
Domains : Interpro (EBI)Band_41_domain    FERM_central    FERM_domain    IQ_motif_EF-hand-BS    Myosin_head_motor_dom    MyTH4_dom    P-loop_NTPase    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)FERM_M (PF00373)    IQ (PF00612)    Myosin_head (PF00063)    MyTH4 (PF00784)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00373    pfam00612    pfam00063    pfam00784    pfam07653   
Domain families : Smart (EMBL)B41 (SM00295)  IQ (SM00015)  MYSc (SM00242)  MyTH4 (SM00139)  SH3 (SM00326)  
Conserved Domain (NCBI)MYO15A
DMDM Disease mutations51168
Blocks (Seattle)MYO15A
SuperfamilyQ9UKN7
Human Protein AtlasENSG00000091536
Peptide AtlasQ9UKN7
HPRD04049
IPIIPI00152380   IPI00908483   IPI00908391   IPI00909192   IPI00922752   IPI00796755   IPI00745826   IPI00384954   IPI01025581   IPI01025464   IPI01025817   IPI00748091   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKN7
IntAct (EBI)Q9UKN7
FunCoupENSG00000091536
BioGRIDMYO15A
STRING (EMBL)MYO15A
ZODIACMYO15A
Ontologies - Pathways
QuickGOQ9UKN7
Ontology : AmiGOmotor activity  actin binding  calmodulin binding  ATP binding  cytoplasm  sensory perception of sound  locomotory behavior  metabolic process  myosin complex  stereocilium  inner ear morphogenesis  extracellular exosome  
Ontology : EGO-EBImotor activity  actin binding  calmodulin binding  ATP binding  cytoplasm  sensory perception of sound  locomotory behavior  metabolic process  myosin complex  stereocilium  inner ear morphogenesis  extracellular exosome  
NDEx NetworkMYO15A
Atlas of Cancer Signalling NetworkMYO15A
Wikipedia pathwaysMYO15A
Orthology - Evolution
OrthoDB51168
GeneTree (enSembl)ENSG00000091536
Phylogenetic Trees/Animal Genes : TreeFamMYO15A
HOVERGENQ9UKN7
HOGENOMQ9UKN7
Homologs : HomoloGeneMYO15A
Homology/Alignments : Family Browser (UCSC)MYO15A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO15A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO15A
dbVarMYO15A
ClinVarMYO15A
1000_GenomesMYO15A 
Exome Variant ServerMYO15A
ExAC (Exome Aggregation Consortium)MYO15A (select the gene name)
Genetic variants : HAPMAP51168
Genomic Variants (DGV)MYO15A [DGVbeta]
DECIPHER (Syndromes)17:18012020-18083116  ENSG00000091536
CONAN: Copy Number AnalysisMYO15A 
Mutations
ICGC Data PortalMYO15A 
TCGA Data PortalMYO15A 
Broad Tumor PortalMYO15A
OASIS PortalMYO15A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO15A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO15A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Retinal and hearing impairment genetic mutation database
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MYO15A
DgiDB (Drug Gene Interaction Database)MYO15A
DoCM (Curated mutations)MYO15A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO15A (select a term)
intoGenMYO15A
Cancer3DMYO15A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600316    602666   
Orphanet12047   
MedgenMYO15A
Genetic Testing Registry MYO15A
NextProtQ9UKN7 [Medical]
TSGene51168
GENETestsMYO15A
Huge Navigator MYO15A [HugePedia]
snp3D : Map Gene to Disease51168
BioCentury BCIQMYO15A
ClinGenMYO15A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51168
Chemical/Pharm GKB GenePA31395
Clinical trialMYO15A
Miscellaneous
canSAR (ICR)MYO15A (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO15A
EVEXMYO15A
GoPubMedMYO15A
iHOPMYO15A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:34:19 CET 2017

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