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MYO18B (myosin XVIIIB)

Identity

Alias_symbol (synonym)BK125H2.1
Other aliasKFS4
HGNC (Hugo) MYO18B
LocusID (NCBI) 84700
Atlas_Id 41481
Location 22q12.1  [Link to chromosome band 22q12]
Location_base_pair Starts at 25742144 and ends at 26031041 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DRG1 (22q12.2) / MYO18B (22q12.1)MYO18B (22q12.1) / UBE2R2 (9p13.3)DRG1 22q12.2 / MYO18B 22q12.1
MYO18B 22q12.1 / UBE2R2 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO18B   18150
Cards
Entrez_Gene (NCBI)MYO18B  84700  myosin XVIIIB
AliasesKFS4
GeneCards (Weizmann)MYO18B
Ensembl hg19 (Hinxton)ENSG00000133454 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133454 [Gene_View]  chr22:25742144-26031041 [Contig_View]  MYO18B [Vega]
ICGC DataPortalENSG00000133454
TCGA cBioPortalMYO18B
AceView (NCBI)MYO18B
Genatlas (Paris)MYO18B
WikiGenes84700
SOURCE (Princeton)MYO18B
Genetics Home Reference (NIH)MYO18B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO18B  -     chr22:25742144-26031041 +  22q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO18B  -     22q12.1   [Description]    (hg19-Feb_2009)
EnsemblMYO18B - 22q12.1 [CytoView hg19]  MYO18B - 22q12.1 [CytoView hg38]
Mapping of homologs : NCBIMYO18B [Mapview hg19]  MYO18B [Mapview hg38]
OMIM607295   616549   
Gene and transcription
Genbank (Entrez)AB042648 AB075376 AJ271918 AJ310931 AK095943
RefSeq transcript (Entrez)NM_001318245 NM_032608
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO18B
Cluster EST : UnigeneHs.417959 [ NCBI ]
CGAP (NCI)Hs.417959
Alternative Splicing GalleryENSG00000133454
Gene ExpressionMYO18B [ NCBI-GEO ]   MYO18B [ EBI - ARRAY_EXPRESS ]   MYO18B [ SEEK ]   MYO18B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO18B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84700
GTEX Portal (Tissue expression)MYO18B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUG5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUG5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUG5
Splice isoforms : SwissVarQ8IUG5
PhosPhoSitePlusQ8IUG5
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    MYO18B    Myosin-like_IQ_dom    Myosin_head_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Myosin_head (PF00063)   
Domain families : Pfam (NCBI)pfam00063   
Domain families : Smart (EMBL)MYSc (SM00242)  
Conserved Domain (NCBI)MYO18B
DMDM Disease mutations84700
Blocks (Seattle)MYO18B
SuperfamilyQ8IUG5
Human Protein AtlasENSG00000133454
Peptide AtlasQ8IUG5
HPRD09529
IPIIPI00874168   IPI01015401   IPI00306929   IPI01015760   IPI01014988   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUG5
IntAct (EBI)Q8IUG5
FunCoupENSG00000133454
BioGRIDMYO18B
STRING (EMBL)MYO18B
ZODIACMYO18B
Ontologies - Pathways
QuickGOQ8IUG5
Ontology : AmiGOmotor activity  actin binding  ATP binding  nucleus  unconventional myosin complex  sarcomere  
Ontology : EGO-EBImotor activity  actin binding  ATP binding  nucleus  unconventional myosin complex  sarcomere  
NDEx NetworkMYO18B
Atlas of Cancer Signalling NetworkMYO18B
Wikipedia pathwaysMYO18B
Orthology - Evolution
OrthoDB84700
GeneTree (enSembl)ENSG00000133454
Phylogenetic Trees/Animal Genes : TreeFamMYO18B
HOVERGENQ8IUG5
HOGENOMQ8IUG5
Homologs : HomoloGeneMYO18B
Homology/Alignments : Family Browser (UCSC)MYO18B
Gene fusions - Rearrangements
Fusion : MitelmanDRG1/MYO18B [22q12.2/22q12.1]  [t(22;22)(q12;q12)]  
Fusion : MitelmanMYO18B/UBE2R2 [22q12.1/9p13.3]  [t(9;22)(p13;q12)]  
Fusion: TCGADRG1 22q12.2 MYO18B 22q12.1 LUSC
Fusion: TCGAMYO18B 22q12.1 UBE2R2 9p13.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO18B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO18B
dbVarMYO18B
ClinVarMYO18B
1000_GenomesMYO18B 
Exome Variant ServerMYO18B
ExAC (Exome Aggregation Consortium)MYO18B (select the gene name)
Genetic variants : HAPMAP84700
Genomic Variants (DGV)MYO18B [DGVbeta]
DECIPHERMYO18B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO18B 
Mutations
ICGC Data PortalMYO18B 
TCGA Data PortalMYO18B 
Broad Tumor PortalMYO18B
OASIS PortalMYO18B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO18B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO18B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO18B
DgiDB (Drug Gene Interaction Database)MYO18B
DoCM (Curated mutations)MYO18B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO18B (select a term)
intoGenMYO18B
Cancer3DMYO18B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607295    616549   
Orphanet23556   
MedgenMYO18B
Genetic Testing Registry MYO18B
NextProtQ8IUG5 [Medical]
TSGene84700
GENETestsMYO18B
Target ValidationMYO18B
Huge Navigator MYO18B [HugePedia]
snp3D : Map Gene to Disease84700
BioCentury BCIQMYO18B
ClinGenMYO18B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84700
Chemical/Pharm GKB GenePA38300
Clinical trialMYO18B
Miscellaneous
canSAR (ICR)MYO18B (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO18B
EVEXMYO18B
GoPubMedMYO18B
iHOPMYO18B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:45:50 CEST 2017

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