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MYO1B (myosin IB)

Identity

Alias_symbol (synonym)myr1
Other aliasMMI-alpha
MMIa
MYH-1c
HGNC (Hugo) MYO1B
LocusID (NCBI) 4430
Atlas_Id 55662
Location 2q32.3  [Link to chromosome band 2q32]
Location_base_pair Starts at 191245276 and ends at 191425389 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL1A1 (17q21.33) / MYO1B (2q32.3)HSPB1 (7q11.23) / MYO1B (2q32.3)LTBP4 (19q13.2) / MYO1B (2q32.3)
MAP4 (3p21.31) / MYO1B (2q32.3)MRPL21 (11q13.3) / MYO1B (2q32.3)MYO1B (2q32.3) / GLS (2q32.2)
MYO1B (2q32.3) / NIPAL3 (1p36.11)MYO1B (2q32.3) / PLEKHG1 (6q25.1)MYO1B (2q32.3) / RHBDD1 (2q36.3)
MYO1B (2q32.3) / SPAG16 (2q34)MYO1B (2q32.3) / STAT4 (2q32.2)MYO1B (2q32.3) / ZNF536 (19q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO1B   7596
Cards
Entrez_Gene (NCBI)MYO1B  4430  myosin IB
AliasesMMI-alpha; MMIa; MYH-1c; myr1
GeneCards (Weizmann)MYO1B
Ensembl hg19 (Hinxton)ENSG00000128641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128641 [Gene_View]  chr2:191245276-191425389 [Contig_View]  MYO1B [Vega]
ICGC DataPortalENSG00000128641
TCGA cBioPortalMYO1B
AceView (NCBI)MYO1B
Genatlas (Paris)MYO1B
WikiGenes4430
SOURCE (Princeton)MYO1B
Genetics Home Reference (NIH)MYO1B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO1B  -     chr2:191245276-191425389 +  2q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO1B  -     2q32.3   [Description]    (hg19-Feb_2009)
EnsemblMYO1B - 2q32.3 [CytoView hg19]  MYO1B - 2q32.3 [CytoView hg38]
Mapping of homologs : NCBIMYO1B [Mapview hg19]  MYO1B [Mapview hg38]
OMIM606537   
Gene and transcription
Genbank (Entrez)AB290176 AI751497 AJ001381 AJ001382 AK000160
RefSeq transcript (Entrez)NM_001130158 NM_001161819 NM_001330237 NM_001330238 NM_012223
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO1B
Cluster EST : UnigeneHs.439620 [ NCBI ]
CGAP (NCI)Hs.439620
Alternative Splicing GalleryENSG00000128641
Gene ExpressionMYO1B [ NCBI-GEO ]   MYO1B [ EBI - ARRAY_EXPRESS ]   MYO1B [ SEEK ]   MYO1B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4430
GTEX Portal (Tissue expression)MYO1B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43795   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43795  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43795
Splice isoforms : SwissVarO43795
PhosPhoSitePlusO43795
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    TH1 (PS51757)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Myosin_head_motor_dom    Myosin_TH1    P-loop_NTPase   
Domain families : Pfam (Sanger)IQ (PF00612)    Myosin_head (PF00063)    Myosin_TH1 (PF06017)   
Domain families : Pfam (NCBI)pfam00612    pfam00063    pfam06017   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  
Conserved Domain (NCBI)MYO1B
DMDM Disease mutations4430
Blocks (Seattle)MYO1B
SuperfamilyO43795
Human Protein AtlasENSG00000128641
Peptide AtlasO43795
HPRD08407
IPIIPI00376344   IPI00414980   IPI00793284   IPI00795618   IPI00917840   IPI00917100   IPI00916949   IPI00917462   
Protein Interaction databases
DIP (DOE-UCLA)O43795
IntAct (EBI)O43795
FunCoupENSG00000128641
BioGRIDMYO1B
STRING (EMBL)MYO1B
ZODIACMYO1B
Ontologies - Pathways
QuickGOO43795
Ontology : AmiGOmicrofilament motor activity  microfilament motor activity  calmodulin binding  ATP binding  ATP binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  cytoplasm  early endosome  actin filament  plasma membrane  plasma membrane  brush border  post-Golgi vesicle-mediated transport  actin filament organization  endosome membrane  myosin complex  actin filament-based movement  filopodium  actin-dependent ATPase activity  trans-Golgi network membrane  apical part of cell  cadherin binding  perinuclear region of cytoplasm  actin filament binding  actin filament bundle assembly  extracellular exosome  cell periphery  
Ontology : EGO-EBImicrofilament motor activity  microfilament motor activity  calmodulin binding  ATP binding  ATP binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  cytoplasm  early endosome  actin filament  plasma membrane  plasma membrane  brush border  post-Golgi vesicle-mediated transport  actin filament organization  endosome membrane  myosin complex  actin filament-based movement  filopodium  actin-dependent ATPase activity  trans-Golgi network membrane  apical part of cell  cadherin binding  perinuclear region of cytoplasm  actin filament binding  actin filament bundle assembly  extracellular exosome  cell periphery  
NDEx NetworkMYO1B
Atlas of Cancer Signalling NetworkMYO1B
Wikipedia pathwaysMYO1B
Orthology - Evolution
OrthoDB4430
GeneTree (enSembl)ENSG00000128641
Phylogenetic Trees/Animal Genes : TreeFamMYO1B
HOVERGENO43795
HOGENOMO43795
Homologs : HomoloGeneMYO1B
Homology/Alignments : Family Browser (UCSC)MYO1B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO1B
dbVarMYO1B
ClinVarMYO1B
1000_GenomesMYO1B 
Exome Variant ServerMYO1B
ExAC (Exome Aggregation Consortium)MYO1B (select the gene name)
Genetic variants : HAPMAP4430
Genomic Variants (DGV)MYO1B [DGVbeta]
DECIPHERMYO1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO1B 
Mutations
ICGC Data PortalMYO1B 
TCGA Data PortalMYO1B 
Broad Tumor PortalMYO1B
OASIS PortalMYO1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO1B
DgiDB (Drug Gene Interaction Database)MYO1B
DoCM (Curated mutations)MYO1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO1B (select a term)
intoGenMYO1B
Cancer3DMYO1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606537   
Orphanet
MedgenMYO1B
Genetic Testing Registry MYO1B
NextProtO43795 [Medical]
TSGene4430
GENETestsMYO1B
Target ValidationMYO1B
Huge Navigator MYO1B [HugePedia]
snp3D : Map Gene to Disease4430
BioCentury BCIQMYO1B
ClinGenMYO1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4430
Chemical/Pharm GKB GenePA31398
Clinical trialMYO1B
Miscellaneous
canSAR (ICR)MYO1B (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO1B
EVEXMYO1B
GoPubMedMYO1B
iHOPMYO1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:45:51 CEST 2017

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