MYO1B (myosin IB)

2015-03-01  

Identity

HGNC
LOCATION
2q32.3
LOCUSID
ALIAS
MMI-alpha,MMIa,MYH-1c,myr1
FUSION GENES

Other Information

Locus ID:

NCBI: 4430
MIM: 606537
HGNC: 7596
Ensembl: ENSG00000128641

Variants:

dbSNP: 4430
ClinVar: 4430
TCGA: ENSG00000128641
COSMIC: MYO1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128641ENST00000304164O43795
ENSG00000128641ENST00000304164B0I1S9
ENSG00000128641ENST00000339514O43795
ENSG00000128641ENST00000392316E9PDF6
ENSG00000128641ENST00000392318O43795
ENSG00000128641ENST00000392318B0I1S9
ENSG00000128641ENST00000418908C9JYW1
ENSG00000128641ENST00000420448C9K0I9
ENSG00000128641ENST00000427152H7C2Y7
ENSG00000128641ENST00000438652C9JUP5
ENSG00000128641ENST00000451437E7EQD9
ENSG00000128641ENST00000634375A0A0U1RRI3

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
185997912008Myosin I can act as a molecular force sensor.99
216666842011Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network.47
124865942002Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia.35
162196892005Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes.33
247096512014Catch-bond behaviour facilitates membrane tubulation by non-processive myosin 1b.15
291155822018Passenger strand of miR-145-3p acts as a tumor-suppressor by targeting MYO1B in head and neck squamous cell carcinoma.14
261956702015Myosin 1b functions as an effector of EphB signaling to control cell repulsion.13
310402422019<i>Toxoplasma</i> Controls Host Cyclin E Expression through the Use of a Novel MYR1-Dependent Effector Protein, HCE1.12
254217512015Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC.10
265455832015MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer.8

Citation

Dessen P

MYO1B (myosin IB)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55662/myo1b