Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MYO1E (myosin IE)

Identity

Alias_symbol (synonym)MYO1C
HuncM-IC
MGC104638
Other aliasFSGS6
HGNC (Hugo) MYO1E
LocusID (NCBI) 4643
Atlas_Id 70630
Location 15q22.2  [Link to chromosome band 15q22]
Location_base_pair Starts at 59135969 and ends at 59372872 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BAZ1A (14q13.1) / MYO1E (15q22.2)MYO1E (15q22.2) / BNIP2 (15q22.2)MYO1E (15q22.2) / HCFC1 (Xq28)
MYO1E (15q22.2) / HNRNPA2B1 (7p15.2)MYO1E (15q22.2) / MYO1E (15q22.2)MYO1E (15q22.2) / USP54 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO1E   7599
Cards
Entrez_Gene (NCBI)MYO1E  4643  myosin IE
AliasesFSGS6; HuncM-IC; MYO1C
GeneCards (Weizmann)MYO1E
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr15:59135969-59372872 [Contig_View]  MYO1E [Vega]
TCGA cBioPortalMYO1E
AceView (NCBI)MYO1E
Genatlas (Paris)MYO1E
WikiGenes4643
SOURCE (Princeton)MYO1E
Genetics Home Reference (NIH)MYO1E
Genomic and cartography
GoldenPath hg38 (UCSC)MYO1E  -     chr15:59135969-59372872 -  15q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO1E  -     15q22.2   [Description]    (hg19-Feb_2009)
EnsemblMYO1E - 15q22.2 [CytoView hg19]  MYO1E - 15q22.2 [CytoView hg38]
Mapping of homologs : NCBIMYO1E [Mapview hg19]  MYO1E [Mapview hg38]
OMIM601479   614131   
Gene and transcription
Genbank (Entrez)AB290177 AK291688 AL707587 BC067835 BC098392
RefSeq transcript (Entrez)NM_004998
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO1E
Cluster EST : UnigeneHs.654506 [ NCBI ]
CGAP (NCI)Hs.654506
Gene ExpressionMYO1E [ NCBI-GEO ]   MYO1E [ EBI - ARRAY_EXPRESS ]   MYO1E [ SEEK ]   MYO1E [ MEM ]
Gene Expression Viewer (FireBrowse)MYO1E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4643
GTEX Portal (Tissue expression)MYO1E
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12965   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12965  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12965
Splice isoforms : SwissVarQ12965
PhosPhoSitePlusQ12965
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    SH3 (PS50002)    TH1 (PS51757)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Myosin_head_motor_dom    Myosin_TH1    P-loop_NTPase    SH3_domain   
Domain families : Pfam (Sanger)Myosin_head (PF00063)    Myosin_TH1 (PF06017)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam00063    pfam06017    pfam00018   
Domain families : Smart (EMBL)MYSc (SM00242)  SH3 (SM00326)  
Conserved Domain (NCBI)MYO1E
DMDM Disease mutations4643
Blocks (Seattle)MYO1E
SuperfamilyQ12965
Peptide AtlasQ12965
HPRD03281
IPIIPI00329672   
Protein Interaction databases
DIP (DOE-UCLA)Q12965
IntAct (EBI)Q12965
BioGRIDMYO1E
STRING (EMBL)MYO1E
ZODIACMYO1E
Ontologies - Pathways
QuickGOQ12965
Ontology : AmiGOmicrofilament motor activity  vasculogenesis  in utero embryonic development  glomerular filtration  motor activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytoskeleton  brush border  cell-cell junction  adherens junction  nitrogen compound metabolic process  endocytosis  actin cytoskeleton  myosin complex  actin filament-based movement  glomerular basement membrane development  phosphatidylinositol binding  post-embryonic hemopoiesis  ATPase activity, coupled  clathrin-coated endocytic vesicle  platelet-derived growth factor receptor signaling pathway  actin filament binding  extracellular exosome  glomerular visceral epithelial cell development  
Ontology : EGO-EBImicrofilament motor activity  vasculogenesis  in utero embryonic development  glomerular filtration  motor activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytoskeleton  brush border  cell-cell junction  adherens junction  nitrogen compound metabolic process  endocytosis  actin cytoskeleton  myosin complex  actin filament-based movement  glomerular basement membrane development  phosphatidylinositol binding  post-embryonic hemopoiesis  ATPase activity, coupled  clathrin-coated endocytic vesicle  platelet-derived growth factor receptor signaling pathway  actin filament binding  extracellular exosome  glomerular visceral epithelial cell development  
NDEx NetworkMYO1E
Atlas of Cancer Signalling NetworkMYO1E
Wikipedia pathwaysMYO1E
Orthology - Evolution
OrthoDB4643
Phylogenetic Trees/Animal Genes : TreeFamMYO1E
HOVERGENQ12965
HOGENOMQ12965
Homologs : HomoloGeneMYO1E
Homology/Alignments : Family Browser (UCSC)MYO1E
Gene fusions - Rearrangements
Fusion: Tumor Portal MYO1E
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO1E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO1E
dbVarMYO1E
ClinVarMYO1E
1000_GenomesMYO1E 
Exome Variant ServerMYO1E
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP4643
Genomic Variants (DGV)MYO1E [DGVbeta]
DECIPHERMYO1E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO1E 
Mutations
ICGC Data PortalMYO1E 
TCGA Data PortalMYO1E 
Broad Tumor PortalMYO1E
OASIS PortalMYO1E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO1E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO1E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO1E
DgiDB (Drug Gene Interaction Database)MYO1E
DoCM (Curated mutations)MYO1E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO1E (select a term)
intoGenMYO1E
Cancer3DMYO1E(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601479    614131   
Orphanet12191   
MedgenMYO1E
Genetic Testing Registry MYO1E
NextProtQ12965 [Medical]
TSGene4643
GENETestsMYO1E
Target ValidationMYO1E
Huge Navigator MYO1E [HugePedia]
snp3D : Map Gene to Disease4643
BioCentury BCIQMYO1E
ClinGenMYO1E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4643
Chemical/Pharm GKB GenePA31401
Clinical trialMYO1E
Miscellaneous
canSAR (ICR)MYO1E (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO1E
EVEXMYO1E
GoPubMedMYO1E
iHOPMYO1E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:18:23 CET 2017

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