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MYO3A (myosin IIIA)

Identity

Alias_namesDFNB30
deafness
Other alias
HGNC (Hugo) MYO3A
LocusID (NCBI) 53904
Atlas_Id 43366
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 25934073 and ends at 26212536 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO3A   7601
Cards
Entrez_Gene (NCBI)MYO3A  53904  myosin IIIA
AliasesDFNB30
GeneCards (Weizmann)MYO3A
Ensembl hg19 (Hinxton)ENSG00000095777 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095777 [Gene_View]  chr10:25934073-26212536 [Contig_View]  MYO3A [Vega]
ICGC DataPortalENSG00000095777
TCGA cBioPortalMYO3A
AceView (NCBI)MYO3A
Genatlas (Paris)MYO3A
WikiGenes53904
SOURCE (Princeton)MYO3A
Genetics Home Reference (NIH)MYO3A
Genomic and cartography
GoldenPath hg38 (UCSC)MYO3A  -     chr10:25934073-26212536 +  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO3A  -     10p12.1   [Description]    (hg19-Feb_2009)
EnsemblMYO3A - 10p12.1 [CytoView hg19]  MYO3A - 10p12.1 [CytoView hg38]
Mapping of homologs : NCBIMYO3A [Mapview hg19]  MYO3A [Mapview hg38]
OMIM606808   607101   
Gene and transcription
Genbank (Entrez)AF229172 AK310468 AK310494 AY101367 BC036079
RefSeq transcript (Entrez)NM_017433
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO3A
Cluster EST : UnigeneHs.662630 [ NCBI ]
CGAP (NCI)Hs.662630
Alternative Splicing GalleryENSG00000095777
Gene ExpressionMYO3A [ NCBI-GEO ]   MYO3A [ EBI - ARRAY_EXPRESS ]   MYO3A [ SEEK ]   MYO3A [ MEM ]
Gene Expression Viewer (FireBrowse)MYO3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53904
GTEX Portal (Tissue expression)MYO3A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NEV4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NEV4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NEV4
Splice isoforms : SwissVarQ8NEV4
PhosPhoSitePlusQ8NEV4
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Kinase-like_dom    Myosin_head_motor_dom    P-loop_NTPase    Prot_kinase_dom    Protein_kinase_ATP_BS   
Domain families : Pfam (Sanger)IQ (PF00612)    Myosin_head (PF00063)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00612    pfam00063    pfam00069   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  S_TKc (SM00220)  
Conserved Domain (NCBI)MYO3A
DMDM Disease mutations53904
Blocks (Seattle)MYO3A
SuperfamilyQ8NEV4
Human Protein AtlasENSG00000095777
Peptide AtlasQ8NEV4
HPRD06008
IPIIPI00185036   IPI00646041   IPI00853424   
Protein Interaction databases
DIP (DOE-UCLA)Q8NEV4
IntAct (EBI)Q8NEV4
FunCoupENSG00000095777
BioGRIDMYO3A
STRING (EMBL)MYO3A
ZODIACMYO3A
Ontologies - Pathways
QuickGOQ8NEV4
Ontology : AmiGOmicrofilament motor activity  microfilament motor activity  actin binding  protein kinase activity  protein serine/threonine kinase activity  calmodulin binding  ATP binding  cytoplasm  visual perception  sensory perception of sound  myosin complex  filopodium  actin-dependent ATPase activity  filamentous actin  ADP binding  protein autophosphorylation  response to stimulus  plus-end directed microfilament motor activity  
Ontology : EGO-EBImicrofilament motor activity  microfilament motor activity  actin binding  protein kinase activity  protein serine/threonine kinase activity  calmodulin binding  ATP binding  cytoplasm  visual perception  sensory perception of sound  myosin complex  filopodium  actin-dependent ATPase activity  filamentous actin  ADP binding  protein autophosphorylation  response to stimulus  plus-end directed microfilament motor activity  
NDEx NetworkMYO3A
Atlas of Cancer Signalling NetworkMYO3A
Wikipedia pathwaysMYO3A
Orthology - Evolution
OrthoDB53904
GeneTree (enSembl)ENSG00000095777
Phylogenetic Trees/Animal Genes : TreeFamMYO3A
HOVERGENQ8NEV4
HOGENOMQ8NEV4
Homologs : HomoloGeneMYO3A
Homology/Alignments : Family Browser (UCSC)MYO3A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO3A
dbVarMYO3A
ClinVarMYO3A
1000_GenomesMYO3A 
Exome Variant ServerMYO3A
ExAC (Exome Aggregation Consortium)MYO3A (select the gene name)
Genetic variants : HAPMAP53904
Genomic Variants (DGV)MYO3A [DGVbeta]
DECIPHERMYO3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO3A 
Mutations
ICGC Data PortalMYO3A 
TCGA Data PortalMYO3A 
Broad Tumor PortalMYO3A
OASIS PortalMYO3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MYO3A
DgiDB (Drug Gene Interaction Database)MYO3A
DoCM (Curated mutations)MYO3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO3A (select a term)
intoGenMYO3A
Cancer3DMYO3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606808    607101   
Orphanet12047   
MedgenMYO3A
Genetic Testing Registry MYO3A
NextProtQ8NEV4 [Medical]
TSGene53904
GENETestsMYO3A
Huge Navigator MYO3A [HugePedia]
snp3D : Map Gene to Disease53904
BioCentury BCIQMYO3A
ClinGenMYO3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD53904
Chemical/Pharm GKB GenePA31405
Clinical trialMYO3A
Miscellaneous
canSAR (ICR)MYO3A (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO3A
EVEXMYO3A
GoPubMedMYO3A
iHOPMYO3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:27:44 CEST 2017

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