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MYO3B (myosin IIIB)

Identity

Other alias-
HGNC (Hugo) MYO3B
LocusID (NCBI) 140469
Atlas_Id 43367
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 170178145 and ends at 170655164 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ITGA6 (2q31.1) / MYO3B (2q31.1)ITGA6 2q31.1 / MYO3B 2q31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO3B   15576
Cards
Entrez_Gene (NCBI)MYO3B  140469  myosin IIIB
Aliases
GeneCards (Weizmann)MYO3B
Ensembl hg19 (Hinxton)ENSG00000071909 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000071909 [Gene_View]  chr2:170178145-170655164 [Contig_View]  MYO3B [Vega]
ICGC DataPortalENSG00000071909
TCGA cBioPortalMYO3B
AceView (NCBI)MYO3B
Genatlas (Paris)MYO3B
WikiGenes140469
SOURCE (Princeton)MYO3B
Genetics Home Reference (NIH)MYO3B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO3B  -     chr2:170178145-170655164 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO3B  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblMYO3B - 2q31.1 [CytoView hg19]  MYO3B - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIMYO3B [Mapview hg19]  MYO3B [Mapview hg38]
OMIM610040   
Gene and transcription
Genbank (Entrez)AF369908 AF391554 AF391555 AF391556 AF391557
RefSeq transcript (Entrez)NM_001083615 NM_001171642 NM_138995
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO3B
Cluster EST : UnigeneHs.671900 [ NCBI ]
CGAP (NCI)Hs.671900
Alternative Splicing GalleryENSG00000071909
Gene ExpressionMYO3B [ NCBI-GEO ]   MYO3B [ EBI - ARRAY_EXPRESS ]   MYO3B [ SEEK ]   MYO3B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140469
GTEX Portal (Tissue expression)MYO3B
Human Protein AtlasENSG00000071909-MYO3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WXR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WXR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WXR4
Splice isoforms : SwissVarQ8WXR4
PhosPhoSitePlusQ8WXR4
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Kinase-like_dom    Myosin_head_motor_dom    P-loop_NTPase    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)IQ (PF00612)    Myosin_head (PF00063)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00612    pfam00063    pfam00069   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  S_TKc (SM00220)  
Conserved Domain (NCBI)MYO3B
DMDM Disease mutations140469
Blocks (Seattle)MYO3B
SuperfamilyQ8WXR4
Human Protein Atlas [tissue]ENSG00000071909-MYO3B [tissue]
Peptide AtlasQ8WXR4
HPRD17623
IPIIPI00337720   IPI00179193   IPI00956214   IPI00217417   IPI00385322   IPI00409999   IPI00827784   IPI00921933   
Protein Interaction databases
DIP (DOE-UCLA)Q8WXR4
IntAct (EBI)Q8WXR4
FunCoupENSG00000071909
BioGRIDMYO3B
STRING (EMBL)MYO3B
ZODIACMYO3B
Ontologies - Pathways
QuickGOQ8WXR4
Ontology : AmiGOmotor activity  actin binding  protein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  visual perception  myosin complex  response to stimulus  
Ontology : EGO-EBImotor activity  actin binding  protein serine/threonine kinase activity  ATP binding  cytoplasm  protein phosphorylation  visual perception  myosin complex  response to stimulus  
NDEx NetworkMYO3B
Atlas of Cancer Signalling NetworkMYO3B
Wikipedia pathwaysMYO3B
Orthology - Evolution
OrthoDB140469
GeneTree (enSembl)ENSG00000071909
Phylogenetic Trees/Animal Genes : TreeFamMYO3B
HOVERGENQ8WXR4
HOGENOMQ8WXR4
Homologs : HomoloGeneMYO3B
Homology/Alignments : Family Browser (UCSC)MYO3B
Gene fusions - Rearrangements
Fusion : MitelmanITGA6/MYO3B [2q31.1/2q31.1]  [t(2;2)(q31;q31)]  
Fusion: TCGA_MDACCITGA6 2q31.1 MYO3B 2q31.1 PRAD
Tumor Fusion PortalMYO3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO3B
dbVarMYO3B
ClinVarMYO3B
1000_GenomesMYO3B 
Exome Variant ServerMYO3B
ExAC (Exome Aggregation Consortium)ENSG00000071909
GNOMAD BrowserENSG00000071909
Genetic variants : HAPMAP140469
Genomic Variants (DGV)MYO3B [DGVbeta]
DECIPHERMYO3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO3B 
Mutations
ICGC Data PortalMYO3B 
TCGA Data PortalMYO3B 
Broad Tumor PortalMYO3B
OASIS PortalMYO3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO3B
DgiDB (Drug Gene Interaction Database)MYO3B
DoCM (Curated mutations)MYO3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO3B (select a term)
intoGenMYO3B
Cancer3DMYO3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610040   
Orphanet
DisGeNETMYO3B
MedgenMYO3B
Genetic Testing Registry MYO3B
NextProtQ8WXR4 [Medical]
TSGene140469
GENETestsMYO3B
Target ValidationMYO3B
Huge Navigator MYO3B [HugePedia]
snp3D : Map Gene to Disease140469
BioCentury BCIQMYO3B
ClinGenMYO3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140469
Chemical/Pharm GKB GenePA31406
Clinical trialMYO3B
Miscellaneous
canSAR (ICR)MYO3B (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO3B
EVEXMYO3B
GoPubMedMYO3B
iHOPMYO3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:25:18 CET 2017

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