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MYO5B (myosin VB)

Identity

Other names-
HGNC (Hugo) MYO5B
LocusID (NCBI) 4645
Location 18q21.1
Location_base_pair Starts at 47349156 and ends at 47721451 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)MYO5B   7603
Cards
Entrez_Gene (NCBI)MYO5B  4645  myosin VB
GeneCards (Weizmann)MYO5B
Ensembl hg19 (Hinxton)ENSG00000167306 [Gene_View]  chr18:47349156-47721451 [Contig_View]  MYO5B [Vega]
Ensembl hg38 (Hinxton)ENSG00000167306 [Gene_View]  chr18:47349156-47721451 [Contig_View]  MYO5B [Vega]
ICGC DataPortalENSG00000167306
cBioPortalMYO5B
AceView (NCBI)MYO5B
Genatlas (Paris)MYO5B
WikiGenes4645
SOURCE (Princeton)MYO5B
Genomic and cartography
GoldenPath hg19 (UCSC)MYO5B  -     chr18:47349156-47721451 -  18q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MYO5B  -     18q21.1   [Description]    (hg38-Dec_2013)
EnsemblMYO5B - 18q21.1 [CytoView hg19]  MYO5B - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBIMYO5B [Mapview hg19]  MYO5B [Mapview hg38]
OMIM251850   606540   
Gene and transcription
Genbank (Entrez)AB032945 AB290160 AK025336 AK093149 AK301976
RefSeq transcript (Entrez)NM_001080467
RefSeq genomic (Entrez)AC_000150 NC_000018 NC_018929 NG_012925 NT_010966 NW_001838468 NW_004929410
Consensus coding sequences : CCDS (NCBI)MYO5B
Cluster EST : UnigeneHs.720076 [ NCBI ]
CGAP (NCI)Hs.720076
Alternative Splicing : Fast-db (Paris)GSHG0014305
Alternative Splicing GalleryENSG00000167306
Gene ExpressionMYO5B [ NCBI-GEO ]     MYO5B [ SEEK ]   MYO5B [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULV0 (Uniprot)
NextProtQ9ULV0  [Medical]
With graphics : InterProQ9ULV0
Splice isoforms : SwissVarQ9ULV0 (Swissvar)
Domaine pattern : Prosite (Expaxy)DILUTE (PS51126)    IQ (PS50096)    MYOSIN_MOTOR (PS51456)   
Domains : Interpro (EBI)Dil_domain    Dilute    IQ_motif_EF-hand-BS    Myosin_head_motor_dom    P-loop_NTPase   
Related proteins : CluSTrQ9ULV0
Domain families : Pfam (Sanger)DIL (PF01843)    IQ (PF00612)    Myosin_head (PF00063)   
Domain families : Pfam (NCBI)pfam01843    pfam00612    pfam00063   
Domain families : Smart (EMBL)IQ (SM00015)  MYSc (SM00242)  
DMDM Disease mutations4645
Blocks (Seattle)Q9ULV0
PDB (SRS)4J5M    4LNZ    4LWZ    4LX0   
PDB (PDBSum)4J5M    4LNZ    4LWZ    4LX0   
PDB (IMB)4J5M    4LNZ    4LWZ    4LX0   
PDB (RSDB)4J5M    4LNZ    4LWZ    4LX0   
Human Protein AtlasENSG00000167306
Peptide AtlasQ9ULV0
IPIIPI00740166   IPI00737500   IPI00479962   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULV0
IntAct (EBI)Q9ULV0
FunCoupENSG00000167306
BioGRIDMYO5B
IntegromeDBMYO5B
STRING (EMBL)MYO5B
Ontologies - Pathways
QuickGOQ9ULV0
Ontology : AmiGOmicrofilament motor activity  actin binding  protein binding  calmodulin binding  ATP binding  water transport  metabolic process  metabolic process  protein transport  vesicle-mediated transport  myosin complex  Rab GTPase binding  cytoplasmic vesicle membrane  protein complex  transmembrane transport  extracellular vesicular exosome  
Ontology : EGO-EBImicrofilament motor activity  actin binding  protein binding  calmodulin binding  ATP binding  water transport  metabolic process  metabolic process  protein transport  vesicle-mediated transport  myosin complex  Rab GTPase binding  cytoplasmic vesicle membrane  protein complex  transmembrane transport  extracellular vesicular exosome  
Protein Interaction DatabaseMYO5B
DoCM (Curated mutations)MYO5B
Wikipedia pathwaysMYO5B
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerMYO5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO5B
dbVarMYO5B
ClinVarMYO5B
1000_GenomesMYO5B 
Exome Variant ServerMYO5B
SNP (GeneSNP Utah)MYO5B
SNP : HGBaseMYO5B
Genetic variants : HAPMAPMYO5B
Genomic VariantsMYO5B  MYO5B [DGVbeta]
Mutations
ICGC Data PortalENSG00000167306 
Somatic Mutations in Cancer : COSMICMYO5B 
CONAN: Copy Number AnalysisMYO5B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)18:47349156-47721451
Mutations and Diseases : HGMDMYO5B
OMIM251850    606540   
MedgenMYO5B
NextProtQ9ULV0 [Medical]
GENETestsMYO5B
Disease Genetic AssociationMYO5B
Huge Navigator MYO5B [HugePedia]  MYO5B [HugeCancerGEM]
snp3D : Map Gene to Disease4645
DGIdb (Drug Gene Interaction db)MYO5B
General knowledge
Homologs : HomoloGeneMYO5B
Homology/Alignments : Family Browser (UCSC)MYO5B
Phylogenetic Trees/Animal Genes : TreeFamMYO5B
Chemical/Protein Interactions : CTD4645
Chemical/Pharm GKB GenePA31408
Clinical trialMYO5B
Cancer Resource (Charite)ENSG00000167306
Other databases
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
CoreMineMYO5B
GoPubMedMYO5B
iHOPMYO5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 00:22:34 CET 2014

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