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MYO7B (myosin VIIB)

Identity

Other alias-
HGNC (Hugo) MYO7B
LocusID (NCBI) 4648
Atlas_Id 70634
Location 2q14.3  [Link to chromosome band 2q14]
Location_base_pair Starts at 127535802 and ends at 127637728 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTSB (8p23.1) / MYO7B (2q14.3)MYO7B (2q14.3) / C8orf58 (8p21.3)MYO7B (2q14.3) / MYO7B (2q14.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO7B   7607
Cards
Entrez_Gene (NCBI)MYO7B  4648  myosin VIIB
Aliases
GeneCards (Weizmann)MYO7B
Ensembl hg19 (Hinxton)ENSG00000169994 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169994 [Gene_View]  chr2:127535802-127637728 [Contig_View]  MYO7B [Vega]
ICGC DataPortalENSG00000169994
TCGA cBioPortalMYO7B
AceView (NCBI)MYO7B
Genatlas (Paris)MYO7B
WikiGenes4648
SOURCE (Princeton)MYO7B
Genetics Home Reference (NIH)MYO7B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO7B  -     chr2:127535802-127637728 +  2q14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO7B  -     2q14.3   [Description]    (hg19-Feb_2009)
EnsemblMYO7B - 2q14.3 [CytoView hg19]  MYO7B - 2q14.3 [CytoView hg38]
Mapping of homologs : NCBIMYO7B [Mapview hg19]  MYO7B [Mapview hg38]
OMIM606541   
Gene and transcription
Genbank (Entrez)AB290182 AK000145 AK074183 BC035615 BC051761
RefSeq transcript (Entrez)NM_001080527 NM_183371
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO7B
Cluster EST : UnigeneHs.154578 [ NCBI ]
CGAP (NCI)Hs.154578
Alternative Splicing GalleryENSG00000169994
Gene ExpressionMYO7B [ NCBI-GEO ]   MYO7B [ EBI - ARRAY_EXPRESS ]   MYO7B [ SEEK ]   MYO7B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4648
GTEX Portal (Tissue expression)MYO7B
Human Protein AtlasENSG00000169994-MYO7B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PIF6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PIF6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PIF6
Splice isoforms : SwissVarQ6PIF6
PhosPhoSitePlusQ6PIF6
Domaine pattern : Prosite (Expaxy)FERM_3 (PS50057)    IQ (PS50096)    MYOSIN_MOTOR (PS51456)    MYTH4 (PS51016)    SH3 (PS50002)   
Domains : Interpro (EBI)Band_41_domain    FERM/acyl-CoA-bd_prot_3-hlx    FERM_central    FERM_domain    IQ_motif_EF-hand-BS    Myosin_head_motor_dom    MyTH4_dom    P-loop_NTPase    PH_dom-like    SH3_2    SH3_domain    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)FERM_M (PF00373)    IQ (PF00612)    Myosin_head (PF00063)    MyTH4 (PF00784)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00373    pfam00612    pfam00063    pfam00784    pfam07653   
Domain families : Smart (EMBL)B41 (SM00295)  IQ (SM00015)  MYSc (SM00242)  MyTH4 (SM00139)  SH3 (SM00326)  
Conserved Domain (NCBI)MYO7B
DMDM Disease mutations4648
Blocks (Seattle)MYO7B
SuperfamilyQ6PIF6
Human Protein Atlas [tissue]ENSG00000169994-MYO7B [tissue]
Peptide AtlasQ6PIF6
IPIIPI00939150   IPI00889512   IPI00738806   IPI01018850   IPI00916099   
Protein Interaction databases
DIP (DOE-UCLA)Q6PIF6
IntAct (EBI)Q6PIF6
FunCoupENSG00000169994
BioGRIDMYO7B
STRING (EMBL)MYO7B
ZODIACMYO7B
Ontologies - Pathways
QuickGOQ6PIF6
Ontology : AmiGOmotor activity  actin binding  protein binding  ATP binding  microvillus  brush border  myosin complex  cell differentiation  extracellular exosome  apical cytoplasm  brush border assembly  
Ontology : EGO-EBImotor activity  actin binding  protein binding  ATP binding  microvillus  brush border  myosin complex  cell differentiation  extracellular exosome  apical cytoplasm  brush border assembly  
NDEx NetworkMYO7B
Atlas of Cancer Signalling NetworkMYO7B
Wikipedia pathwaysMYO7B
Orthology - Evolution
OrthoDB4648
GeneTree (enSembl)ENSG00000169994
Phylogenetic Trees/Animal Genes : TreeFamMYO7B
HOVERGENQ6PIF6
HOGENOMQ6PIF6
Homologs : HomoloGeneMYO7B
Homology/Alignments : Family Browser (UCSC)MYO7B
Gene fusions - Rearrangements
Tumor Fusion PortalMYO7B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO7B
dbVarMYO7B
ClinVarMYO7B
1000_GenomesMYO7B 
Exome Variant ServerMYO7B
ExAC (Exome Aggregation Consortium)ENSG00000169994
GNOMAD BrowserENSG00000169994
Genetic variants : HAPMAP4648
Genomic Variants (DGV)MYO7B [DGVbeta]
DECIPHERMYO7B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO7B 
Mutations
ICGC Data PortalMYO7B 
TCGA Data PortalMYO7B 
Broad Tumor PortalMYO7B
OASIS PortalMYO7B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO7B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO7B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO7B
DgiDB (Drug Gene Interaction Database)MYO7B
DoCM (Curated mutations)MYO7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO7B (select a term)
intoGenMYO7B
Cancer3DMYO7B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606541   
Orphanet
DisGeNETMYO7B
MedgenMYO7B
Genetic Testing Registry MYO7B
NextProtQ6PIF6 [Medical]
TSGene4648
GENETestsMYO7B
Target ValidationMYO7B
Huge Navigator MYO7B [HugePedia]
snp3D : Map Gene to Disease4648
BioCentury BCIQMYO7B
ClinGenMYO7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4648
Chemical/Pharm GKB GenePA31412
Clinical trialMYO7B
Miscellaneous
canSAR (ICR)MYO7B (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO7B
EVEXMYO7B
GoPubMedMYO7B
iHOPMYO7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:05:50 CET 2017

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