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MYO9B (myosin IXB)

Identity

Alias (NCBI)CELIAC4
MYR5
HGNC (Hugo) MYO9B
HGNC Previous nameCELIAC4
LocusID (NCBI) 4650
Atlas_Id 53330
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 17075777 and ends at 17213286 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARHGEF18 (19p13.2) / MYO9B (19p13.11)C1R (12p13.31) / MYO9B (19p13.11)KIAA1191 (5q35.2) / MYO9B (19p13.11)
MYO9B (19p13.11) / ADAM12 (10q26.2)MYO9B (19p13.11) / ATP13A1 (19p13.11)MYO9B (19p13.11) / FCHO1 (19p13.11)
MYO9B (19p13.11) / MYO9B (19p13.11)MYO9B (19p13.11) / PNN (14q21.1)MYO9B (19p13.11) / PPM1A (14q23.1)
RAB22A (20q13.32) / MYO9B (19p13.11)VPS13B (8q22.2) / MYO9B (19p13.11)ARHGEF18 19p13.2 / MYO9B 19p13.11
MYO9B 19p13.11 / ATP13A1 19p13.11MYO9B 19p13.11 / PNN 14q21.1VPS13B 8q22.2 / MYO9B 19p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MYO9B   7609
Cards
Entrez_Gene (NCBI)MYO9B    myosin IXB
AliasesCELIAC4; MYR5
GeneCards (Weizmann)MYO9B
Ensembl hg19 (Hinxton)ENSG00000099331 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099331 [Gene_View]  ENSG00000099331 [Sequence]  chr19:17075777-17213286 [Contig_View]  MYO9B [Vega]
ICGC DataPortalENSG00000099331
TCGA cBioPortalMYO9B
AceView (NCBI)MYO9B
Genatlas (Paris)MYO9B
SOURCE (Princeton)MYO9B
Genetics Home Reference (NIH)MYO9B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO9B  -     chr19:17075777-17213286 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO9B  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathMYO9B - 19p13.11 [CytoView hg19]  MYO9B - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000099331
Genome Data Viewer NCBIMYO9B [Mapview hg19]  
OMIM602129   609753   
Gene and transcription
Genbank (Entrez)AB209997 AB290184 AF020267 AF143684 AK002201
RefSeq transcript (Entrez)NM_001130065 NM_004145
Consensus coding sequences : CCDS (NCBI)MYO9B
Gene ExpressionMYO9B [ NCBI-GEO ]   MYO9B [ EBI - ARRAY_EXPRESS ]   MYO9B [ SEEK ]   MYO9B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO9B [ Firebrowse - Broad ]
GenevisibleExpression of MYO9B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4650
GTEX Portal (Tissue expression)MYO9B
Human Protein AtlasENSG00000099331-MYO9B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13459   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13459  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13459
PhosPhoSitePlusQ13459
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    RA (PS50200)    RHOGAP (PS50238)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    Kinesin_motor_dom_sf    MYO9B    Myosin_head_motor_dom    MYSc_Myo9    P-loop_NTPase    PE/DAG-bd    RA_dom    Rho_GTPase_activation_prot    RhoGAP_dom    Ubiquitin-like_domsf   
Domain families : Pfam (Sanger)IQ (PF00612)    Myosin_head (PF00063)    RA (PF00788)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00612    pfam00063    pfam00788    pfam00620   
Domain families : Smart (EMBL)C1 (SM00109)  IQ (SM00015)  MYSc (SM00242)  RA (SM00314)  RhoGAP (SM00324)  
Conserved Domain (NCBI)MYO9B
PDB (RSDB)5C5S    5HPY   
PDB Europe5C5S    5HPY   
PDB (PDBSum)5C5S    5HPY   
PDB (IMB)5C5S    5HPY   
Structural Biology KnowledgeBase5C5S    5HPY   
SCOP (Structural Classification of Proteins)5C5S    5HPY   
CATH (Classification of proteins structures)5C5S    5HPY   
SuperfamilyQ13459
AlphaFold pdb e-kbQ13459   
Human Protein Atlas [tissue]ENSG00000099331-MYO9B [tissue]
HPRD03677
Protein Interaction databases
DIP (DOE-UCLA)Q13459
IntAct (EBI)Q13459
BioGRIDMYO9B
STRING (EMBL)MYO9B
ZODIACMYO9B
Ontologies - Pathways
QuickGOQ13459
Ontology : AmiGOmicrofilament motor activity  actin binding  GTPase activator activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytosol  cytosol  actin filament  cell cortex  Rho protein signal transduction  actin cytoskeleton  membrane  myosin complex  ATPase  actin filament-based movement  actin filament-based movement  small GTPase binding  ARF protein signal transduction  regulation of Rho protein signal transduction  Roundabout signaling pathway  protein homodimerization activity  ADP binding  metal ion binding  perinuclear region of cytoplasm  Roundabout binding  regulation of catalytic activity  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBImicrofilament motor activity  actin binding  GTPase activator activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytosol  cytosol  actin filament  cell cortex  Rho protein signal transduction  actin cytoskeleton  membrane  myosin complex  ATPase  actin filament-based movement  actin filament-based movement  small GTPase binding  ARF protein signal transduction  regulation of Rho protein signal transduction  Roundabout signaling pathway  protein homodimerization activity  ADP binding  metal ion binding  perinuclear region of cytoplasm  Roundabout binding  regulation of catalytic activity  regulation of small GTPase mediated signal transduction  
NDEx NetworkMYO9B
Atlas of Cancer Signalling NetworkMYO9B
Wikipedia pathwaysMYO9B
Orthology - Evolution
OrthoDB4650
GeneTree (enSembl)ENSG00000099331
Phylogenetic Trees/Animal Genes : TreeFamMYO9B
Homologs : HomoloGeneMYO9B
Homology/Alignments : Family Browser (UCSC)MYO9B
Gene fusions - Rearrangements
Fusion : MitelmanARHGEF18/MYO9B [19p13.2/19p13.11]  
Fusion : MitelmanMYO9B/ATP13A1 [19p13.11/19p13.11]  
Fusion : MitelmanMYO9B/FCHO1 [19p13.11/19p13.11]  
Fusion : MitelmanMYO9B/PNN [19p13.11/14q21.1]  
Fusion : MitelmanRAB22A/MYO9B [20q13.32/19p13.11]  
Fusion : MitelmanVPS13B/MYO9B [8q22.2/19p13.11]  
Fusion : QuiverMYO9B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO9B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO9B
dbVarMYO9B
ClinVarMYO9B
MonarchMYO9B
1000_GenomesMYO9B 
Exome Variant ServerMYO9B
GNOMAD BrowserENSG00000099331
Varsome BrowserMYO9B
ACMGMYO9B variants
VarityQ13459
Genomic Variants (DGV)MYO9B [DGVbeta]
DECIPHERMYO9B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO9B 
Mutations
ICGC Data PortalMYO9B 
TCGA Data PortalMYO9B 
Broad Tumor PortalMYO9B
OASIS PortalMYO9B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO9B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMYO9B
Mutations and Diseases : HGMDMYO9B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMYO9B
DgiDB (Drug Gene Interaction Database)MYO9B
DoCM (Curated mutations)MYO9B
CIViC (Clinical Interpretations of Variants in Cancer)MYO9B
Cancer3DMYO9B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602129    609753   
Orphanet
DisGeNETMYO9B
MedgenMYO9B
Genetic Testing Registry MYO9B
NextProtQ13459 [Medical]
GENETestsMYO9B
Target ValidationMYO9B
Huge Navigator MYO9B [HugePedia]
ClinGenMYO9B
Clinical trials, drugs, therapy
MyCancerGenomeMYO9B
Protein Interactions : CTDMYO9B
Pharm GKB GenePA31414
PharosQ13459
Clinical trialMYO9B
Miscellaneous
canSAR (ICR)MYO9B
HarmonizomeMYO9B
DataMed IndexMYO9B
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMYO9B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:21:51 CEST 2021

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