Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MYO9B (myosin IXB)

Identity

Alias_namesCELIAC4
Other aliasMYR5
HGNC (Hugo) MYO9B
LocusID (NCBI) 4650
Atlas_Id 53330
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 17075781 and ends at 17213295 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARHGEF18 (19p13.2) / MYO9B (19p13.11)C1R (12p13.31) / MYO9B (19p13.11)KIAA1191 (5q35.2) / MYO9B (19p13.11)
MYO9B (19p13.11) / ADAM12 (10q26.2)MYO9B (19p13.11) / ATP13A1 (19p13.11)MYO9B (19p13.11) / FCHO1 (19p13.11)
MYO9B (19p13.11) / MYO9B (19p13.11)MYO9B (19p13.11) / PNN (14q21.1)MYO9B (19p13.11) / PPM1A (14q23.1)
RAB22A (20q13.32) / MYO9B (19p13.11)VPS13B (8q22.2) / MYO9B (19p13.11)ARHGEF18 19p13.2 / MYO9B 19p13.11
MYO9B 19p13.11 / ATP13A1 19p13.11MYO9B 19p13.11 / PNN 14q21.1VPS13B 8q22.2 / MYO9B 19p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYO9B   7609
Cards
Entrez_Gene (NCBI)MYO9B  4650  myosin IXB
AliasesCELIAC4; MYR5
GeneCards (Weizmann)MYO9B
Ensembl hg19 (Hinxton)ENSG00000099331 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099331 [Gene_View]  chr19:17075781-17213295 [Contig_View]  MYO9B [Vega]
ICGC DataPortalENSG00000099331
TCGA cBioPortalMYO9B
AceView (NCBI)MYO9B
Genatlas (Paris)MYO9B
WikiGenes4650
SOURCE (Princeton)MYO9B
Genetics Home Reference (NIH)MYO9B
Genomic and cartography
GoldenPath hg38 (UCSC)MYO9B  -     chr19:17075781-17213295 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYO9B  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblMYO9B - 19p13.11 [CytoView hg19]  MYO9B - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIMYO9B [Mapview hg19]  MYO9B [Mapview hg38]
OMIM602129   609753   
Gene and transcription
Genbank (Entrez)AB209997 AB290184 AF020267 AF143684 AK002201
RefSeq transcript (Entrez)NM_001130065 NM_004145
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYO9B
Cluster EST : UnigeneHs.123198 [ NCBI ]
CGAP (NCI)Hs.123198
Alternative Splicing GalleryENSG00000099331
Gene ExpressionMYO9B [ NCBI-GEO ]   MYO9B [ EBI - ARRAY_EXPRESS ]   MYO9B [ SEEK ]   MYO9B [ MEM ]
Gene Expression Viewer (FireBrowse)MYO9B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4650
GTEX Portal (Tissue expression)MYO9B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13459   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13459  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13459
Splice isoforms : SwissVarQ13459
PhosPhoSitePlusQ13459
Domaine pattern : Prosite (Expaxy)IQ (PS50096)    MYOSIN_MOTOR (PS51456)    RA (PS50200)    RHOGAP (PS50238)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)IQ_motif_EF-hand-BS    MYO9B    Myosin_head_motor_dom    P-loop_NTPase    PE/DAG-bd    RA_dom    Rho_GTPase_activation_prot    RhoGAP_dom    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)IQ (PF00612)    Myosin_head (PF00063)    RA (PF00788)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam00612    pfam00063    pfam00788    pfam00620   
Domain families : Smart (EMBL)C1 (SM00109)  IQ (SM00015)  MYSc (SM00242)  RA (SM00314)  RhoGAP (SM00324)  
Conserved Domain (NCBI)MYO9B
DMDM Disease mutations4650
Blocks (Seattle)MYO9B
PDB (SRS)5C5S    5HPY   
PDB (PDBSum)5C5S    5HPY   
PDB (IMB)5C5S    5HPY   
PDB (RSDB)5C5S    5HPY   
Structural Biology KnowledgeBase5C5S    5HPY   
SCOP (Structural Classification of Proteins)5C5S    5HPY   
CATH (Classification of proteins structures)5C5S    5HPY   
SuperfamilyQ13459
Human Protein AtlasENSG00000099331
Peptide AtlasQ13459
HPRD03677
IPIIPI00336047   IPI00306933   IPI00978167   
Protein Interaction databases
DIP (DOE-UCLA)Q13459
IntAct (EBI)Q13459
FunCoupENSG00000099331
BioGRIDMYO9B
STRING (EMBL)MYO9B
ZODIACMYO9B
Ontologies - Pathways
QuickGOQ13459
Ontology : AmiGOmicrofilament motor activity  actin binding  GTPase activator activity  GTPase activator activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytosol  cytosol  actin filament  cell cortex  Rho protein signal transduction  actin cytoskeleton  membrane  myosin complex  ATPase activity  Rho GTPase binding  actin filament-based movement  actin filament-based movement  ARF protein signal transduction  regulation of Rho protein signal transduction  Roundabout signaling pathway  protein homodimerization activity  ADP binding  positive regulation of GTPase activity  metal ion binding  perinuclear region of cytoplasm  Roundabout binding  regulation of small GTPase mediated signal transduction  
Ontology : EGO-EBImicrofilament motor activity  actin binding  GTPase activator activity  GTPase activator activity  protein binding  calmodulin binding  ATP binding  cytoplasm  cytosol  cytosol  actin filament  cell cortex  Rho protein signal transduction  actin cytoskeleton  membrane  myosin complex  ATPase activity  Rho GTPase binding  actin filament-based movement  actin filament-based movement  ARF protein signal transduction  regulation of Rho protein signal transduction  Roundabout signaling pathway  protein homodimerization activity  ADP binding  positive regulation of GTPase activity  metal ion binding  perinuclear region of cytoplasm  Roundabout binding  regulation of small GTPase mediated signal transduction  
NDEx NetworkMYO9B
Atlas of Cancer Signalling NetworkMYO9B
Wikipedia pathwaysMYO9B
Orthology - Evolution
OrthoDB4650
GeneTree (enSembl)ENSG00000099331
Phylogenetic Trees/Animal Genes : TreeFamMYO9B
HOVERGENQ13459
HOGENOMQ13459
Homologs : HomoloGeneMYO9B
Homology/Alignments : Family Browser (UCSC)MYO9B
Gene fusions - Rearrangements
Fusion : MitelmanARHGEF18/MYO9B [19p13.2/19p13.11]  [t(19;19)(p13;p13)]  
Fusion : MitelmanMYO9B/ATP13A1 [19p13.11/19p13.11]  [t(19;19)(p13;p13)]  
Fusion : MitelmanMYO9B/FCHO1 [19p13.11/19p13.11]  [del(19)(p13p13)]  [t(19;19)(p13;p13)]  
Fusion : MitelmanMYO9B/PNN [19p13.11/14q21.1]  [t(14;19)(q21;p13)]  
Fusion : MitelmanRAB22A/MYO9B [20q13.32/19p13.11]  [t(19;20)(p13;q13)]  
Fusion : MitelmanVPS13B/MYO9B [8q22.2/19p13.11]  [t(8;19)(q22;p13)]  
Fusion: TCGAARHGEF18 19p13.2 MYO9B 19p13.11 BRCA
Fusion: TCGAMYO9B 19p13.11 ATP13A1 19p13.11 OV
Fusion: TCGAMYO9B 19p13.11 PNN 14q21.1 BRCA
Fusion: TCGAVPS13B 8q22.2 MYO9B 19p13.11 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYO9B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYO9B
dbVarMYO9B
ClinVarMYO9B
1000_GenomesMYO9B 
Exome Variant ServerMYO9B
ExAC (Exome Aggregation Consortium)MYO9B (select the gene name)
Genetic variants : HAPMAP4650
Genomic Variants (DGV)MYO9B [DGVbeta]
DECIPHERMYO9B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYO9B 
Mutations
ICGC Data PortalMYO9B 
TCGA Data PortalMYO9B 
Broad Tumor PortalMYO9B
OASIS PortalMYO9B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYO9B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYO9B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYO9B
DgiDB (Drug Gene Interaction Database)MYO9B
DoCM (Curated mutations)MYO9B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYO9B (select a term)
intoGenMYO9B
Cancer3DMYO9B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602129    609753   
Orphanet
MedgenMYO9B
Genetic Testing Registry MYO9B
NextProtQ13459 [Medical]
TSGene4650
GENETestsMYO9B
Target ValidationMYO9B
Huge Navigator MYO9B [HugePedia]
snp3D : Map Gene to Disease4650
BioCentury BCIQMYO9B
ClinGenMYO9B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4650
Chemical/Pharm GKB GenePA31414
Clinical trialMYO9B
Miscellaneous
canSAR (ICR)MYO9B (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYO9B
EVEXMYO9B
GoPubMedMYO9B
iHOPMYO9B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:01:01 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.