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MYSM1 (Myb like, SWIRM and MPN domains 1)

Identity

Alias_namesMyb-like, SWIRM and MPN domains 1
Alias_symbol (synonym)KIAA1915
Other alias2A-DUB
2ADUB
HGNC (Hugo) MYSM1
LocusID (NCBI) 114803
Atlas_Id 70642
Location 1p32.1  [Link to chromosome band 1p32]
Location_base_pair Starts at 58654739 and ends at 58700075 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MYSM1 (1p32.1) / ALG14 (1p21.3)MYSM1 (1p32.1) / APOM (6p21.33)MYSM1 ALG14
MYSM1 APOM

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYSM1   29401
Cards
Entrez_Gene (NCBI)MYSM1  114803  Myb like, SWIRM and MPN domains 1
Aliases2A-DUB; 2ADUB
GeneCards (Weizmann)MYSM1
Ensembl hg19 (Hinxton)ENSG00000162601 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162601 [Gene_View]  chr1:58654739-58700075 [Contig_View]  MYSM1 [Vega]
ICGC DataPortalENSG00000162601
TCGA cBioPortalMYSM1
AceView (NCBI)MYSM1
Genatlas (Paris)MYSM1
WikiGenes114803
SOURCE (Princeton)MYSM1
Genetics Home Reference (NIH)MYSM1
Genomic and cartography
GoldenPath hg38 (UCSC)MYSM1  -     chr1:58654739-58700075 -  1p32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYSM1  -     1p32.1   [Description]    (hg19-Feb_2009)
EnsemblMYSM1 - 1p32.1 [CytoView hg19]  MYSM1 - 1p32.1 [CytoView hg38]
Mapping of homologs : NCBIMYSM1 [Mapview hg19]  MYSM1 [Mapview hg38]
OMIM612176   
Gene and transcription
Genbank (Entrez)AB067502 AK126835 AK292919 BC037536 BC167849
RefSeq transcript (Entrez)NM_001085487
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYSM1
Cluster EST : UnigeneHs.744921 [ NCBI ]
CGAP (NCI)Hs.744921
Alternative Splicing GalleryENSG00000162601
Gene ExpressionMYSM1 [ NCBI-GEO ]   MYSM1 [ EBI - ARRAY_EXPRESS ]   MYSM1 [ SEEK ]   MYSM1 [ MEM ]
Gene Expression Viewer (FireBrowse)MYSM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114803
GTEX Portal (Tissue expression)MYSM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VVJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VVJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VVJ2
Splice isoforms : SwissVarQ5VVJ2
Catalytic activity : Enzyme3.4.19.- [ Enzyme-Expasy ]   3.4.19.-3.4.19.- [ IntEnz-EBI ]   3.4.19.- [ BRENDA ]   3.4.19.- [ KEGG ]   
PhosPhoSitePlusQ5VVJ2
Domaine pattern : Prosite (Expaxy)SANT (PS51293)    SWIRM (PS50934)   
Domains : Interpro (EBI)Homeobox-like    JAMM/MPN+_dom    MYSM1    SANT/Myb    SANT_dom    SWIRM    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)JAB (PF01398)    Myb_DNA-binding (PF00249)    SWIRM (PF04433)   
Domain families : Pfam (NCBI)pfam01398    pfam00249    pfam04433   
Domain families : Smart (EMBL)JAB_MPN (SM00232)  SANT (SM00717)  
Conserved Domain (NCBI)MYSM1
DMDM Disease mutations114803
Blocks (Seattle)MYSM1
PDB (SRS)2CU7    2DCE   
PDB (PDBSum)2CU7    2DCE   
PDB (IMB)2CU7    2DCE   
PDB (RSDB)2CU7    2DCE   
Structural Biology KnowledgeBase2CU7    2DCE   
SCOP (Structural Classification of Proteins)2CU7    2DCE   
CATH (Classification of proteins structures)2CU7    2DCE   
SuperfamilyQ5VVJ2
Human Protein AtlasENSG00000162601
Peptide AtlasQ5VVJ2
IPIIPI00044725   IPI00747702   IPI00740485   
Protein Interaction databases
DIP (DOE-UCLA)Q5VVJ2
IntAct (EBI)Q5VVJ2
FunCoupENSG00000162601
BioGRIDMYSM1
STRING (EMBL)MYSM1
ZODIACMYSM1
Ontologies - Pathways
QuickGOQ5VVJ2
Ontology : AmiGODNA binding  transcription coactivator activity  thiol-dependent ubiquitin-specific protease activity  nucleus  nucleoplasm  nucleoplasm  plasma membrane  chromatin remodeling  transcription, DNA-templated  metallopeptidase activity  protein deubiquitination  regulation of cell migration  protein complex binding  monoubiquitinated histone H2A deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  histone binding  pigmentation  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  regulation of hair follicle development  
Ontology : EGO-EBIDNA binding  transcription coactivator activity  thiol-dependent ubiquitin-specific protease activity  nucleus  nucleoplasm  nucleoplasm  plasma membrane  chromatin remodeling  transcription, DNA-templated  metallopeptidase activity  protein deubiquitination  regulation of cell migration  protein complex binding  monoubiquitinated histone H2A deubiquitination  thiol-dependent ubiquitinyl hydrolase activity  histone binding  pigmentation  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  regulation of hair follicle development  
NDEx NetworkMYSM1
Atlas of Cancer Signalling NetworkMYSM1
Wikipedia pathwaysMYSM1
Orthology - Evolution
OrthoDB114803
GeneTree (enSembl)ENSG00000162601
Phylogenetic Trees/Animal Genes : TreeFamMYSM1
HOVERGENQ5VVJ2
HOGENOMQ5VVJ2
Homologs : HomoloGeneMYSM1
Homology/Alignments : Family Browser (UCSC)MYSM1
Gene fusions - Rearrangements
Fusion: TCGAMYSM1 ALG14
Fusion: TCGAMYSM1 APOM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYSM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYSM1
dbVarMYSM1
ClinVarMYSM1
1000_GenomesMYSM1 
Exome Variant ServerMYSM1
ExAC (Exome Aggregation Consortium)MYSM1 (select the gene name)
Genetic variants : HAPMAP114803
Genomic Variants (DGV)MYSM1 [DGVbeta]
DECIPHERMYSM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYSM1 
Mutations
ICGC Data PortalMYSM1 
TCGA Data PortalMYSM1 
Broad Tumor PortalMYSM1
OASIS PortalMYSM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYSM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYSM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYSM1
DgiDB (Drug Gene Interaction Database)MYSM1
DoCM (Curated mutations)MYSM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYSM1 (select a term)
intoGenMYSM1
Cancer3DMYSM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612176   
Orphanet
MedgenMYSM1
Genetic Testing Registry MYSM1
NextProtQ5VVJ2 [Medical]
TSGene114803
GENETestsMYSM1
Huge Navigator MYSM1 [HugePedia]
snp3D : Map Gene to Disease114803
BioCentury BCIQMYSM1
ClinGenMYSM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114803
Chemical/Pharm GKB GenePA142671301
Clinical trialMYSM1
Miscellaneous
canSAR (ICR)MYSM1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYSM1
EVEXMYSM1
GoPubMedMYSM1
iHOPMYSM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:44:26 CEST 2017

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