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MYT1 (myelin transcription factor 1)

Identity

Alias (NCBI)C20orf36
MTF1
MYTI
NZF2
PLPB1
ZC2H2C1
ZC2HC4A
HGNC (Hugo) MYT1
HGNC Alias symbMTF1
MYTI
ZC2HC4A
NZF2
ZC2H2C1
HGNC Alias nameneural zinc finger transcription factor 2
HGNC Previous namePLPB1
LocusID (NCBI) 4661
Atlas_Id 50898
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 64164452 and ends at 64242253 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
STX16 (20q13.32) / MYT1 (20q13.33)STX16 20q13.32 / MYT1 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MYT1   7622
Cards
Entrez_Gene (NCBI)MYT1    myelin transcription factor 1
AliasesC20orf36; MTF1; MYTI; NZF2; 
PLPB1; ZC2H2C1; ZC2HC4A
GeneCards (Weizmann)MYT1
Ensembl hg19 (Hinxton)ENSG00000196132 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196132 [Gene_View]  ENSG00000196132 [Sequence]  chr20:64164452-64242253 [Contig_View]  MYT1 [Vega]
ICGC DataPortalENSG00000196132
TCGA cBioPortalMYT1
AceView (NCBI)MYT1
Genatlas (Paris)MYT1
SOURCE (Princeton)MYT1
Genetics Home Reference (NIH)MYT1
Genomic and cartography
GoldenPath hg38 (UCSC)MYT1  -     chr20:64164452-64242253 +  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYT1  -     20q13.33   [Description]    (hg19-Feb_2009)
GoldenPathMYT1 - 20q13.33 [CytoView hg19]  MYT1 - 20q13.33 [CytoView hg38]
ImmunoBaseENSG00000196132
Genome Data Viewer NCBIMYT1 [Mapview hg19]  
OMIM600379   
Gene and transcription
Genbank (Entrez)AB020642 BC018917 BC053638 BC062313 M96980
RefSeq transcript (Entrez)NM_004535
Consensus coding sequences : CCDS (NCBI)MYT1
Gene ExpressionMYT1 [ NCBI-GEO ]   MYT1 [ EBI - ARRAY_EXPRESS ]   MYT1 [ SEEK ]   MYT1 [ MEM ]
Gene Expression Viewer (FireBrowse)MYT1 [ Firebrowse - Broad ]
GenevisibleExpression of MYT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4661
GTEX Portal (Tissue expression)MYT1
Human Protein AtlasENSG00000196132-MYT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01538   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01538  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01538
PhosPhoSitePlusQ01538
Domaine pattern : Prosite (Expaxy)ZF_CCHHC (PS51802)   
Domains : Interpro (EBI)Myelin_TF    Znf_C2H2C    Znf_C2H2C_sf   
Domain families : Pfam (Sanger)MYT1 (PF08474)    zf-C2HC (PF01530)   
Domain families : Pfam (NCBI)pfam08474    pfam01530   
Conserved Domain (NCBI)MYT1
SuperfamilyQ01538
AlphaFold pdb e-kbQ01538   
Human Protein Atlas [tissue]ENSG00000196132-MYT1 [tissue]
HPRD02659
Protein Interaction databases
DIP (DOE-UCLA)Q01538
IntAct (EBI)Q01538
BioGRIDMYT1
STRING (EMBL)MYT1
ZODIACMYT1
Ontologies - Pathways
QuickGOQ01538
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleus  nucleoplasm  cytosol  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  nervous system development  zinc ion binding  cell differentiation  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  nucleus  nucleoplasm  cytosol  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  nervous system development  zinc ion binding  cell differentiation  
Pathways : BIOCARTAcdc25 and chk1 Regulatory Pathway in response to DNA damage [Genes]    Cell Cycle: G2/M Checkpoint [Genes]    RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage [Genes]    How Progesterone Initiates the Oocyte Maturation [Genes]   
NDEx NetworkMYT1
Atlas of Cancer Signalling NetworkMYT1
Wikipedia pathwaysMYT1
Orthology - Evolution
OrthoDB4661
GeneTree (enSembl)ENSG00000196132
Phylogenetic Trees/Animal Genes : TreeFamMYT1
Homologs : HomoloGeneMYT1
Homology/Alignments : Family Browser (UCSC)MYT1
Gene fusions - Rearrangements
Fusion : MitelmanSTX16/MYT1 [20q13.32/20q13.33]  
Fusion : QuiverMYT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYT1
dbVarMYT1
ClinVarMYT1
MonarchMYT1
1000_GenomesMYT1 
Exome Variant ServerMYT1
GNOMAD BrowserENSG00000196132
Varsome BrowserMYT1
ACMGMYT1 variants
VarityQ01538
Genomic Variants (DGV)MYT1 [DGVbeta]
DECIPHERMYT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYT1 
Mutations
ICGC Data PortalMYT1 
TCGA Data PortalMYT1 
Broad Tumor PortalMYT1
OASIS PortalMYT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYT1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMYT1
Mutations and Diseases : HGMDMYT1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMYT1
DgiDB (Drug Gene Interaction Database)MYT1
DoCM (Curated mutations)MYT1
CIViC (Clinical Interpretations of Variants in Cancer)MYT1
Cancer3DMYT1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600379   
Orphanet
DisGeNETMYT1
MedgenMYT1
Genetic Testing Registry MYT1
NextProtQ01538 [Medical]
GENETestsMYT1
Target ValidationMYT1
Huge Navigator MYT1 [HugePedia]
ClinGenMYT1
Clinical trials, drugs, therapy
MyCancerGenomeMYT1
Protein Interactions : CTDMYT1
Pharm GKB GenePA31426
PharosQ01538
Clinical trialMYT1
Miscellaneous
canSAR (ICR)MYT1
HarmonizomeMYT1
DataMed IndexMYT1
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMYT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:21:54 CEST 2021

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