Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

MYT1L (myelin transcription factor 1 like)

Identity

Alias_symbol (synonym)KIAA1106
NZF1
ZC2HC4B
ZC2H2C2
Other aliasMRD39
myT1-L
HGNC (Hugo) MYT1L
LocusID (NCBI) 23040
Atlas_Id 53639
Location 2p25.3  [Link to chromosome band 2p25]
Location_base_pair Starts at 1789113 and ends at 2331313 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADD3 (10q25.1) / MYT1L (2p25.3)MYT1L (2p25.3) / CAMTA1 (1p36.31)MYT1L (2p25.3) / FN1 (2q35)
MYT1L (2p25.3) / IDH3B (20p13)MYT1L (2p25.3) / KCNH7 (2q24.2)MYT1L (2p25.3) / OTUD5 (Xp11.23)
NELL1 (11p15.1) / MYT1L (2p25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MYT1L   7623
Cards
Entrez_Gene (NCBI)MYT1L  23040  myelin transcription factor 1 like
AliasesMRD39; NZF1; ZC2H2C2; ZC2HC4B; 
myT1-L
GeneCards (Weizmann)MYT1L
Ensembl hg19 (Hinxton)ENSG00000186487 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186487 [Gene_View]  chr2:1789113-2331313 [Contig_View]  MYT1L [Vega]
ICGC DataPortalENSG00000186487
TCGA cBioPortalMYT1L
AceView (NCBI)MYT1L
Genatlas (Paris)MYT1L
WikiGenes23040
SOURCE (Princeton)MYT1L
Genetics Home Reference (NIH)MYT1L
Genomic and cartography
GoldenPath hg38 (UCSC)MYT1L  -     chr2:1789113-2331313 -  2p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MYT1L  -     2p25.3   [Description]    (hg19-Feb_2009)
EnsemblMYT1L - 2p25.3 [CytoView hg19]  MYT1L - 2p25.3 [CytoView hg38]
Mapping of homologs : NCBIMYT1L [Mapview hg19]  MYT1L [Mapview hg38]
OMIM613084   616521   
Gene and transcription
Genbank (Entrez)AB029029 AB073885 AF036943 AK299571 AK307797
RefSeq transcript (Entrez)NM_001303052 NM_001329844 NM_001329845 NM_001329846 NM_001329847 NM_001329848 NM_001329849 NM_001329851 NM_001329852 NM_015025
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MYT1L
Cluster EST : UnigeneHs.669852 [ NCBI ]
CGAP (NCI)Hs.669852
Alternative Splicing GalleryENSG00000186487
Gene ExpressionMYT1L [ NCBI-GEO ]   MYT1L [ EBI - ARRAY_EXPRESS ]   MYT1L [ SEEK ]   MYT1L [ MEM ]
Gene Expression Viewer (FireBrowse)MYT1L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23040
GTEX Portal (Tissue expression)MYT1L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UL68   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UL68  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UL68
Splice isoforms : SwissVarQ9UL68
PhosPhoSitePlusQ9UL68
Domaine pattern : Prosite (Expaxy)ZF_CCHHC (PS51802)   
Domains : Interpro (EBI)Myelin_TF    Znf_C2HC   
Domain families : Pfam (Sanger)MYT1 (PF08474)    zf-C2HC (PF01530)   
Domain families : Pfam (NCBI)pfam08474    pfam01530   
Conserved Domain (NCBI)MYT1L
DMDM Disease mutations23040
Blocks (Seattle)MYT1L
SuperfamilyQ9UL68
Human Protein AtlasENSG00000186487
Peptide AtlasQ9UL68
HPRD14797
IPIIPI00007843   IPI00651769   IPI00939946   IPI00942362   IPI00644005   
Protein Interaction databases
DIP (DOE-UCLA)Q9UL68
IntAct (EBI)Q9UL68
FunCoupENSG00000186487
BioGRIDMYT1L
STRING (EMBL)MYT1L
ZODIACMYT1L
Ontologies - Pathways
QuickGOQ9UL68
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  zinc ion binding  cell differentiation  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  nervous system development  zinc ion binding  cell differentiation  
NDEx NetworkMYT1L
Atlas of Cancer Signalling NetworkMYT1L
Wikipedia pathwaysMYT1L
Orthology - Evolution
OrthoDB23040
GeneTree (enSembl)ENSG00000186487
Phylogenetic Trees/Animal Genes : TreeFamMYT1L
HOVERGENQ9UL68
HOGENOMQ9UL68
Homologs : HomoloGeneMYT1L
Homology/Alignments : Family Browser (UCSC)MYT1L
Gene fusions - Rearrangements
Fusion Cancer (Beijing)MYT1L [2p25.3]  -  FN1 [2q35]  [FUSC002878]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMYT1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MYT1L
dbVarMYT1L
ClinVarMYT1L
1000_GenomesMYT1L 
Exome Variant ServerMYT1L
ExAC (Exome Aggregation Consortium)MYT1L (select the gene name)
Genetic variants : HAPMAP23040
Genomic Variants (DGV)MYT1L [DGVbeta]
DECIPHERMYT1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMYT1L 
Mutations
ICGC Data PortalMYT1L 
TCGA Data PortalMYT1L 
Broad Tumor PortalMYT1L
OASIS PortalMYT1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMYT1L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMYT1L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MYT1L
DgiDB (Drug Gene Interaction Database)MYT1L
DoCM (Curated mutations)MYT1L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MYT1L (select a term)
intoGenMYT1L
Cancer3DMYT1L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613084    616521   
Orphanet
MedgenMYT1L
Genetic Testing Registry MYT1L
NextProtQ9UL68 [Medical]
TSGene23040
GENETestsMYT1L
Target ValidationMYT1L
Huge Navigator MYT1L [HugePedia]
snp3D : Map Gene to Disease23040
BioCentury BCIQMYT1L
ClinGenMYT1L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23040
Chemical/Pharm GKB GenePA31427
Clinical trialMYT1L
Miscellaneous
canSAR (ICR)MYT1L (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMYT1L
EVEXMYT1L
GoPubMedMYT1L
iHOPMYT1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:45:56 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.