Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MZF1 (myeloid zinc finger 1)

Identity

Alias_namesZNF42
zinc finger protein 42 (myeloid-specific retinoic acid-responsive)
Alias_symbol (synonym)ZSCAN6
MZF1B
MZF-1
Zfp98
Other aliasZFP98
HGNC (Hugo) MZF1
LocusID (NCBI) 7593
Atlas_Id 51559
Location 19q13.43  [Link to chromosome band 19q13]
Location_base_pair Starts at 58561917 and ends at 58573575 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MZF1 (19q13.43) / CCDC105 (19p13.12)MZF1 19q13.43 / CCDC105 19p13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MZF1   13108
Cards
Entrez_Gene (NCBI)MZF1  7593  myeloid zinc finger 1
AliasesMZF-1; MZF1B; ZFP98; ZNF42; 
ZSCAN6
GeneCards (Weizmann)MZF1
Ensembl hg19 (Hinxton)ENSG00000099326 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099326 [Gene_View]  chr19:58561917-58573575 [Contig_View]  MZF1 [Vega]
ICGC DataPortalENSG00000099326
TCGA cBioPortalMZF1
AceView (NCBI)MZF1
Genatlas (Paris)MZF1
WikiGenes7593
SOURCE (Princeton)MZF1
Genetics Home Reference (NIH)MZF1
Genomic and cartography
GoldenPath hg38 (UCSC)MZF1  -     chr19:58561917-58573575 -  19q13.43   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MZF1  -     19q13.43   [Description]    (hg19-Feb_2009)
EnsemblMZF1 - 19q13.43 [CytoView hg19]  MZF1 - 19q13.43 [CytoView hg38]
Mapping of homologs : NCBIMZF1 [Mapview hg19]  MZF1 [Mapview hg38]
OMIM194550   
Gene and transcription
Genbank (Entrez)AB209481 AF055077 AF055078 AF147345 AK308893
RefSeq transcript (Entrez)NM_001267033 NM_003422 NM_198055
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MZF1
Cluster EST : UnigeneHs.684624 [ NCBI ]
CGAP (NCI)Hs.684624
Alternative Splicing GalleryENSG00000099326
Gene ExpressionMZF1 [ NCBI-GEO ]   MZF1 [ EBI - ARRAY_EXPRESS ]   MZF1 [ SEEK ]   MZF1 [ MEM ]
Gene Expression Viewer (FireBrowse)MZF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7593
GTEX Portal (Tissue expression)MZF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28698   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28698  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28698
Splice isoforms : SwissVarP28698
PhosPhoSitePlusP28698
Domaine pattern : Prosite (Expaxy)SCAN_BOX (PS50804)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Retrov_capsid_C    SCAN_dom    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)SCAN (PF02023)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam02023    pfam00096   
Domain families : Smart (EMBL)SCAN (SM00431)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)MZF1
DMDM Disease mutations7593
Blocks (Seattle)MZF1
PDB (SRS)2FI2   
PDB (PDBSum)2FI2   
PDB (IMB)2FI2   
PDB (RSDB)2FI2   
Structural Biology KnowledgeBase2FI2   
SCOP (Structural Classification of Proteins)2FI2   
CATH (Classification of proteins structures)2FI2   
SuperfamilyP28698
Human Protein AtlasENSG00000099326
Peptide AtlasP28698
HPRD01930
IPIIPI00004569   IPI00063385   IPI00556207   IPI00385450   
Protein Interaction databases
DIP (DOE-UCLA)P28698
IntAct (EBI)P28698
FunCoupENSG00000099326
BioGRIDMZF1
STRING (EMBL)MZF1
ZODIACMZF1
Ontologies - Pathways
QuickGOP28698
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  protein homodimerization activity  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  protein homodimerization activity  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
Pathways : BIOCARTAOverview of telomerase protein component gene hTert Transcriptional Regulation [Genes]   
NDEx NetworkMZF1
Atlas of Cancer Signalling NetworkMZF1
Wikipedia pathwaysMZF1
Orthology - Evolution
OrthoDB7593
GeneTree (enSembl)ENSG00000099326
Phylogenetic Trees/Animal Genes : TreeFamMZF1
HOVERGENP28698
HOGENOMP28698
Homologs : HomoloGeneMZF1
Homology/Alignments : Family Browser (UCSC)MZF1
Gene fusions - Rearrangements
Fusion : MitelmanMZF1/CCDC105 [19q13.43/19p13.12]  
Fusion: TCGAMZF1 19q13.43 CCDC105 19p13.12 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMZF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MZF1
dbVarMZF1
ClinVarMZF1
1000_GenomesMZF1 
Exome Variant ServerMZF1
ExAC (Exome Aggregation Consortium)MZF1 (select the gene name)
Genetic variants : HAPMAP7593
Genomic Variants (DGV)MZF1 [DGVbeta]
DECIPHERMZF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMZF1 
Mutations
ICGC Data PortalMZF1 
TCGA Data PortalMZF1 
Broad Tumor PortalMZF1
OASIS PortalMZF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMZF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMZF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MZF1
DgiDB (Drug Gene Interaction Database)MZF1
DoCM (Curated mutations)MZF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MZF1 (select a term)
intoGenMZF1
Cancer3DMZF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM194550   
Orphanet
MedgenMZF1
Genetic Testing Registry MZF1
NextProtP28698 [Medical]
TSGene7593
GENETestsMZF1
Target ValidationMZF1
Huge Navigator MZF1 [HugePedia]
snp3D : Map Gene to Disease7593
BioCentury BCIQMZF1
ClinGenMZF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7593
Chemical/Pharm GKB GenePA37683
Clinical trialMZF1
Miscellaneous
canSAR (ICR)MZF1 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMZF1
EVEXMZF1
GoPubMedMZF1
iHOPMZF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:01:03 CEST 2017

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