MZF1 (myeloid zinc finger 1)

2010-07-01  

Identity

HGNC
LOCATION
19q13.43
LOCUSID
ALIAS
MZF-1,MZF1B,ZFP98,ZNF42,ZSCAN6
FUSION GENES

Other Information

Locus ID:

NCBI: 7593
MIM: 194550
HGNC: 13108
Ensembl: ENSG00000099326

Variants:

dbSNP: 7593
ClinVar: 7593
TCGA: ENSG00000099326
COSMIC: MZF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099326ENST00000215057P28698
ENSG00000099326ENST00000215057A0A024R4T5
ENSG00000099326ENST00000594108M0R1U5
ENSG00000099326ENST00000594234P28698
ENSG00000099326ENST00000596039M0R2C0
ENSG00000099326ENST00000599369P28698
ENSG00000099326ENST00000599369A0A024R4T5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
224644432012ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.51
201450422010Myeloid zinc finger 1 induces migration, invasion, and in vivo metastasis through Axl gene expression in solid cancer.47
298428852018m6A demethylase FTO facilitates tumor progression in lung squamous cell carcinoma by regulating MZF1 expression.29
247937892015The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss.27
155417322005Sp1/Sp3 and the myeloid zinc finger gene MZF1 regulate the human N-cadherin promoter in osteoblasts.21
228465782012Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells.21
254259702014Up-regulation of FOXM1 by E6 oncoprotein through the MZF1/NKX2-1 axis is required for human papillomavirus-associated tumorigenesis.21
162978762006PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells.20
252845862015Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress.18
259038352015Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.18

Citation

Dessen P

MZF1 (myeloid zinc finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-07-01

Online version: http://atlasgeneticsoncology.org/gene/51559/mzf1