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MZF1 (myeloid zinc finger 1)

Identity

Alias (NCBI)MZF-1
MZF1B
ZFP98
ZNF42
ZSCAN6
HGNC (Hugo) MZF1
HGNC Alias symbZSCAN6
MZF1B
MZF-1
Zfp98
HGNC Previous nameZNF42
HGNC Previous namezinc finger protein 42 (myeloid-specific retinoic acid-responsive)
LocusID (NCBI) 7593
Atlas_Id 51559
Location 19q13.43  [Link to chromosome band 19q13]
Location_base_pair Starts at 58561933 and ends at 58573335 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MZF1 (19q13.43) / CCDC105 (19p13.12)MZF1 19q13.43 / CCDC105 19p13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MZF1   13108
Cards
Entrez_Gene (NCBI)MZF1    myeloid zinc finger 1
AliasesMZF-1; MZF1B; ZFP98; ZNF42; 
ZSCAN6
GeneCards (Weizmann)MZF1
Ensembl hg19 (Hinxton)ENSG00000099326 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099326 [Gene_View]  ENSG00000099326 [Sequence]  chr19:58561933-58573335 [Contig_View]  MZF1 [Vega]
ICGC DataPortalENSG00000099326
TCGA cBioPortalMZF1
AceView (NCBI)MZF1
Genatlas (Paris)MZF1
SOURCE (Princeton)MZF1
Genetics Home Reference (NIH)MZF1
Genomic and cartography
GoldenPath hg38 (UCSC)MZF1  -     chr19:58561933-58573335 -  19q13.43   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MZF1  -     19q13.43   [Description]    (hg19-Feb_2009)
GoldenPathMZF1 - 19q13.43 [CytoView hg19]  MZF1 - 19q13.43 [CytoView hg38]
ImmunoBaseENSG00000099326
Genome Data Viewer NCBIMZF1 [Mapview hg19]  
OMIM194550   
Gene and transcription
Genbank (Entrez)AB209481 AF055077 AF055078 AF147345 AK308893
RefSeq transcript (Entrez)NM_001267033 NM_003422 NM_198055
Consensus coding sequences : CCDS (NCBI)MZF1
Gene ExpressionMZF1 [ NCBI-GEO ]   MZF1 [ EBI - ARRAY_EXPRESS ]   MZF1 [ SEEK ]   MZF1 [ MEM ]
Gene Expression Viewer (FireBrowse)MZF1 [ Firebrowse - Broad ]
GenevisibleExpression of MZF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7593
GTEX Portal (Tissue expression)MZF1
Human Protein AtlasENSG00000099326-MZF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28698   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28698  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28698
PhosPhoSitePlusP28698
Domaine pattern : Prosite (Expaxy)SCAN_BOX (PS50804)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)SCAN_dom    SCAN_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)SCAN (PF02023)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam02023    pfam00096   
Domain families : Smart (EMBL)SCAN (SM00431)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)MZF1
PDB (RSDB)2FI2   
PDB Europe2FI2   
PDB (PDBSum)2FI2   
PDB (IMB)2FI2   
Structural Biology KnowledgeBase2FI2   
SCOP (Structural Classification of Proteins)2FI2   
CATH (Classification of proteins structures)2FI2   
SuperfamilyP28698
AlphaFold pdb e-kbP28698   
Human Protein Atlas [tissue]ENSG00000099326-MZF1 [tissue]
HPRD01930
Protein Interaction databases
DIP (DOE-UCLA)P28698
IntAct (EBI)P28698
BioGRIDMZF1
STRING (EMBL)MZF1
ZODIACMZF1
Ontologies - Pathways
QuickGOP28698
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription, DNA-templated  protein homodimerization activity  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleoplasm  regulation of transcription, DNA-templated  regulation of transcription, DNA-templated  protein homodimerization activity  positive regulation of transcription by RNA polymerase II  metal ion binding  
Pathways : BIOCARTAOverview of telomerase protein component gene hTert Transcriptional Regulation [Genes]   
NDEx NetworkMZF1
Atlas of Cancer Signalling NetworkMZF1
Wikipedia pathwaysMZF1
Orthology - Evolution
OrthoDB7593
GeneTree (enSembl)ENSG00000099326
Phylogenetic Trees/Animal Genes : TreeFamMZF1
Homologs : HomoloGeneMZF1
Homology/Alignments : Family Browser (UCSC)MZF1
Gene fusions - Rearrangements
Fusion : MitelmanMZF1/CCDC105 [19q13.43/19p13.12]  
Fusion : QuiverMZF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMZF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MZF1
dbVarMZF1
ClinVarMZF1
MonarchMZF1
1000_GenomesMZF1 
Exome Variant ServerMZF1
GNOMAD BrowserENSG00000099326
Varsome BrowserMZF1
ACMGMZF1 variants
VarityP28698
Genomic Variants (DGV)MZF1 [DGVbeta]
DECIPHERMZF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMZF1 
Mutations
ICGC Data PortalMZF1 
TCGA Data PortalMZF1 
Broad Tumor PortalMZF1
OASIS PortalMZF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMZF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMZF1
Mutations and Diseases : HGMDMZF1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMZF1
DgiDB (Drug Gene Interaction Database)MZF1
DoCM (Curated mutations)MZF1
CIViC (Clinical Interpretations of Variants in Cancer)MZF1
Cancer3DMZF1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM194550   
Orphanet
DisGeNETMZF1
MedgenMZF1
Genetic Testing Registry MZF1
NextProtP28698 [Medical]
GENETestsMZF1
Target ValidationMZF1
Huge Navigator MZF1 [HugePedia]
ClinGenMZF1
Clinical trials, drugs, therapy
MyCancerGenomeMZF1
Protein Interactions : CTDMZF1
Pharm GKB GenePA37683
PharosP28698
Clinical trialMZF1
Miscellaneous
canSAR (ICR)MZF1
HarmonizomeMZF1
DataMed IndexMZF1
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMZF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:21:55 CEST 2021

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