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N4BP2 (NEDD4 binding protein 2)

Identity

Alias_symbol (synonym)B3BP
Other alias
HGNC (Hugo) N4BP2
LocusID (NCBI) 55728
Atlas_Id 41489
Location 4p14  [Link to chromosome band 4p14]
Location_base_pair Starts at 40058524 and ends at 40159872 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RHOH (4p14) / N4BP2 (4p14)RHOH 4p14 / N4BP2 4p14

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)N4BP2   29851
Cards
Entrez_Gene (NCBI)N4BP2  55728  NEDD4 binding protein 2
AliasesB3BP
GeneCards (Weizmann)N4BP2
Ensembl hg19 (Hinxton)ENSG00000078177 [Gene_View]  chr4:40058524-40159872 [Contig_View]  N4BP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000078177 [Gene_View]  chr4:40058524-40159872 [Contig_View]  N4BP2 [Vega]
ICGC DataPortalENSG00000078177
TCGA cBioPortalN4BP2
AceView (NCBI)N4BP2
Genatlas (Paris)N4BP2
WikiGenes55728
SOURCE (Princeton)N4BP2
Genetics Home Reference (NIH)N4BP2
Genomic and cartography
GoldenPath hg19 (UCSC)N4BP2  -     chr4:40058524-40159872 +  4p14   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)N4BP2  -     4p14   [Description]    (hg38-Dec_2013)
EnsemblN4BP2 - 4p14 [CytoView hg19]  N4BP2 - 4p14 [CytoView hg38]
Mapping of homologs : NCBIN4BP2 [Mapview hg19]  N4BP2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB037834 AB371584 AK001542 AU129951 AW135590
RefSeq transcript (Entrez)NM_001318359 NM_018177
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006238 NW_004929317
Consensus coding sequences : CCDS (NCBI)N4BP2
Cluster EST : UnigeneHs.736026 [ NCBI ]
CGAP (NCI)Hs.736026
Alternative Splicing GalleryENSG00000078177
Gene ExpressionN4BP2 [ NCBI-GEO ]   N4BP2 [ EBI - ARRAY_EXPRESS ]   N4BP2 [ SEEK ]   N4BP2 [ MEM ]
Gene Expression Viewer (FireBrowse)N4BP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55728
GTEX Portal (Tissue expression)N4BP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UW6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UW6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UW6
Splice isoforms : SwissVarQ86UW6
Catalytic activity : Enzyme3.-.-.- [ Enzyme-Expasy ]   3.-.-.-3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   
PhosPhoSitePlusQ86UW6
Domaine pattern : Prosite (Expaxy)CUE (PS51140)    SMR (PS50828)   
Domains : Interpro (EBI)CUE    DUF1771    P-loop_NTPase    Smr_dom    UBA-like   
Domain families : Pfam (Sanger)DUF1771 (PF08590)    Smr (PF01713)   
Domain families : Pfam (NCBI)pfam08590    pfam01713   
Conserved Domain (NCBI)N4BP2
DMDM Disease mutations55728
Blocks (Seattle)N4BP2
PDB (SRS)2D9I    2VKC    3BHB    3FAU   
PDB (PDBSum)2D9I    2VKC    3BHB    3FAU   
PDB (IMB)2D9I    2VKC    3BHB    3FAU   
PDB (RSDB)2D9I    2VKC    3BHB    3FAU   
Structural Biology KnowledgeBase2D9I    2VKC    3BHB    3FAU   
SCOP (Structural Classification of Proteins)2D9I    2VKC    3BHB    3FAU   
CATH (Classification of proteins structures)2D9I    2VKC    3BHB    3FAU   
SuperfamilyQ86UW6
Human Protein AtlasENSG00000078177
Peptide AtlasQ86UW6
HPRD11382
IPIIPI00328825   IPI00409742   IPI01025728   IPI00964050   IPI00964303   
Protein Interaction databases
DIP (DOE-UCLA)Q86UW6
IntAct (EBI)Q86UW6
FunCoupENSG00000078177
BioGRIDN4BP2
STRING (EMBL)N4BP2
ZODIACN4BP2
Ontologies - Pathways
QuickGOQ86UW6
Ontology : AmiGOendonuclease activity  protein binding  ATP binding  cytosol  phosphorylation  ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIendonuclease activity  protein binding  ATP binding  cytosol  phosphorylation  ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkN4BP2
Atlas of Cancer Signalling NetworkN4BP2
Wikipedia pathwaysN4BP2
Orthology - Evolution
OrthoDB55728
GeneTree (enSembl)ENSG00000078177
Phylogenetic Trees/Animal Genes : TreeFamN4BP2
HOVERGENQ86UW6
HOGENOMQ86UW6
Homologs : HomoloGeneN4BP2
Homology/Alignments : Family Browser (UCSC)N4BP2
Gene fusions - Rearrangements
Fusion: TCGARHOH 4p14 N4BP2 4p14 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerN4BP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)N4BP2
dbVarN4BP2
ClinVarN4BP2
1000_GenomesN4BP2 
Exome Variant ServerN4BP2
ExAC (Exome Aggregation Consortium)N4BP2 (select the gene name)
Genetic variants : HAPMAP55728
Genomic Variants (DGV)N4BP2 [DGVbeta]
DECIPHER (Syndromes)4:40058524-40159872  ENSG00000078177
CONAN: Copy Number AnalysisN4BP2 
Mutations
ICGC Data PortalN4BP2 
TCGA Data PortalN4BP2 
Broad Tumor PortalN4BP2
OASIS PortalN4BP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICN4BP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDN4BP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch N4BP2
DgiDB (Drug Gene Interaction Database)N4BP2
DoCM (Curated mutations)N4BP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)N4BP2 (select a term)
intoGenN4BP2
Cancer3DN4BP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenN4BP2
Genetic Testing Registry N4BP2
NextProtQ86UW6 [Medical]
TSGene55728
GENETestsN4BP2
Huge Navigator N4BP2 [HugePedia]
snp3D : Map Gene to Disease55728
BioCentury BCIQN4BP2
ClinGenN4BP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55728
Chemical/Pharm GKB GenePA162396580
Clinical trialN4BP2
Miscellaneous
canSAR (ICR)N4BP2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineN4BP2
EVEXN4BP2
GoPubMedN4BP2
iHOPN4BP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:11:33 CEST 2017

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