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N6AMT1 (N-6 adenine-specific DNA methyltransferase 1 (putative))

Identity

Alias_namesC21orf127
HEMK2
chromosome 21 open reading frame 127
HemK methyltransferase family member 2
Alias_symbol (synonym)PRED28
N6AMT
MTQ2
Other aliasm.HsaHemK2P
HGNC (Hugo) N6AMT1
LocusID (NCBI) 29104
Atlas_Id 70654
Location 21q21.3  [Link to chromosome band 21q21]
Location_base_pair Starts at 28876064 and ends at 28885373 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)N6AMT1   16021
Cards
Entrez_Gene (NCBI)N6AMT1  29104  N-6 adenine-specific DNA methyltransferase 1 (putative)
AliasesC21orf127; HEMK2; MTQ2; N6AMT; 
PRED28; m.HsaHemK2P
GeneCards (Weizmann)N6AMT1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr21:28876064-28885373 [Contig_View]  N6AMT1 [Vega]
TCGA cBioPortalN6AMT1
AceView (NCBI)N6AMT1
Genatlas (Paris)N6AMT1
WikiGenes29104
SOURCE (Princeton)N6AMT1
Genetics Home Reference (NIH)N6AMT1
Genomic and cartography
GoldenPath hg38 (UCSC)N6AMT1  -     chr21:28876064-28885373 -  21q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)N6AMT1  -     21q21.3   [Description]    (hg19-Feb_2009)
EnsemblN6AMT1 - 21q21.3 [CytoView hg19]  N6AMT1 - 21q21.3 [CytoView hg38]
Mapping of homologs : NCBIN6AMT1 [Mapview hg19]  N6AMT1 [Mapview hg38]
OMIM614553   
Gene and transcription
Genbank (Entrez)AA825430 AF139682 AK021678 AK092128 AK225515
RefSeq transcript (Entrez)NM_013240 NM_182749
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)N6AMT1
Cluster EST : UnigeneHs.163846 [ NCBI ]
CGAP (NCI)Hs.163846
Gene ExpressionN6AMT1 [ NCBI-GEO ]   N6AMT1 [ EBI - ARRAY_EXPRESS ]   N6AMT1 [ SEEK ]   N6AMT1 [ MEM ]
Gene Expression Viewer (FireBrowse)N6AMT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29104
GTEX Portal (Tissue expression)N6AMT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5N5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5N5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5N5
Splice isoforms : SwissVarQ9Y5N5
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ9Y5N5
Domaine pattern : Prosite (Expaxy)N6_MTASE (PS00092)   
Domains : Interpro (EBI)DNA_methylase_N6_adenine_CS    PrmC-related    SAM-dependent_MTases    Small_mtfrase_dom   
Domain families : Pfam (Sanger)MTS (PF05175)   
Domain families : Pfam (NCBI)pfam05175   
Conserved Domain (NCBI)N6AMT1
DMDM Disease mutations29104
Blocks (Seattle)N6AMT1
SuperfamilyQ9Y5N5
Peptide AtlasQ9Y5N5
HPRD10739
IPIIPI00001640   IPI00101308   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5N5
IntAct (EBI)Q9Y5N5
BioGRIDN6AMT1
STRING (EMBL)N6AMT1
ZODIACN6AMT1
Ontologies - Pathways
QuickGOQ9Y5N5
Ontology : AmiGOnucleic acid binding  protein binding  cytoplasm  cytosol  translational termination  protein methylation  protein methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  positive regulation of cell growth  methylation  protein complex  
Ontology : EGO-EBInucleic acid binding  protein binding  cytoplasm  cytosol  translational termination  protein methylation  protein methyltransferase activity  S-adenosylmethionine-dependent methyltransferase activity  positive regulation of cell growth  methylation  protein complex  
NDEx NetworkN6AMT1
Atlas of Cancer Signalling NetworkN6AMT1
Wikipedia pathwaysN6AMT1
Orthology - Evolution
OrthoDB29104
Phylogenetic Trees/Animal Genes : TreeFamN6AMT1
HOVERGENQ9Y5N5
HOGENOMQ9Y5N5
Homologs : HomoloGeneN6AMT1
Homology/Alignments : Family Browser (UCSC)N6AMT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerN6AMT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)N6AMT1
dbVarN6AMT1
ClinVarN6AMT1
1000_GenomesN6AMT1 
Exome Variant ServerN6AMT1
ExAC (Exome Aggregation Consortium)N6AMT1 (select the gene name)
Genetic variants : HAPMAP29104
Genomic Variants (DGV)N6AMT1 [DGVbeta]
DECIPHERN6AMT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisN6AMT1 
Mutations
ICGC Data PortalN6AMT1 
TCGA Data PortalN6AMT1 
Broad Tumor PortalN6AMT1
OASIS PortalN6AMT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICN6AMT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDN6AMT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch N6AMT1
DgiDB (Drug Gene Interaction Database)N6AMT1
DoCM (Curated mutations)N6AMT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)N6AMT1 (select a term)
intoGenN6AMT1
Cancer3DN6AMT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614553   
Orphanet
MedgenN6AMT1
Genetic Testing Registry N6AMT1
NextProtQ9Y5N5 [Medical]
TSGene29104
GENETestsN6AMT1
Target ValidationN6AMT1
Huge Navigator N6AMT1 [HugePedia]
snp3D : Map Gene to Disease29104
BioCentury BCIQN6AMT1
ClinGenN6AMT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29104
Chemical/Pharm GKB GenePA162396656
Clinical trialN6AMT1
Miscellaneous
canSAR (ICR)N6AMT1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineN6AMT1
EVEXN6AMT1
GoPubMedN6AMT1
iHOPN6AMT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:09 CEST 2017

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