NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit)

2014-11-01  

Identity

HGNC
LOCATION
14q22.3
LOCUSID
ALIAS
C14orf35,MAK3,Mak3p,NAT12,NAT12P
FUSION GENES

Other Information

Locus ID:

NCBI: 122830
MIM: 617989
HGNC: 19844
Ensembl: ENSG00000139977

Variants:

dbSNP: 122830
ClinVar: 122830
TCGA: ENSG00000139977
COSMIC: NAA30

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139977ENST00000298406J3KNC2
ENSG00000139977ENST00000554703G3V3I2
ENSG00000139977ENST00000555166B4DK34
ENSG00000139977ENST00000556492Q147X3

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
193985762009Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization.46
262926632015Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells.9
276943312016A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity.6
292477992018Identification of an alternatively spliced nuclear isoform of human N-terminal acetyltransferase Naa30.2
283564832017Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization.1

Citation

Dessen P

NAA30 (N-alpha-acetyltransferase 30, NatC catalytic subunit)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70658/naa30